Abstract
Scientific revolutions require a series of paradigm shifts that are promoted by a series of discoveries. These discoveries, paradigm shifts, and scientific revolutions are dependent on timing, environment, and innovative pioneers. More than 50 years ago, a series of discoveries led to such a paradigm shift at the University of Minnesota which in turn revolutionized the field of cardiovascular medicine forever. Today, this spirit of innovation and discovery is alive and thriving at the Lillehei Heart Institute at the University of Minnesota.
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References
Gott, V. L. (2005). Lillehei, Lewis, and Wangensteen: The right mix for giant achievements in cardiac surgery. Annals of Thoracic Surgery, 79, S2210–S2213.
Cooley, D. A. (1999). C. Walton Lillehei, the “father of open heart surgery”. Circulation, 100, 1364–1365.
Lillehei, C. W., Varco, R. L., Cohen, M., Warden, H. E., Patton, C., & Moller, J. H. (1986). The first open-heart repairs of ventricular septal defect, atrioventricular communis, and teralogy of Fallot using extracorporeal circulation by cross-circulation: a 30-year follow-up. Annals of Thoracic Surgery, 41, 4–21.
Dewall, R. A., Warden, H. E., Melby, J. C., Minot, H., Varco, R. L., & Lillehei, C. W. (1957). Physiological responses during total body perfusion with a pump-oxygenator; studies in one hundred twenty patients undergoing open cardiac surgery. Journal of the American Medical Association, 165, 1788–1792.
Gott, V. L. (1989). C. Walton Lillehei and his trainees: One man’s legacy to cardiothoracic surgery. Journal of Thoracic and Cardiovascular Surgery, 98, 846–851.
Katz, A. M. (2008). The “modern” view of heart failure. Circulation: Heart Failure, 1, 63–71.
Garry, D. J., & Olson, E. N. (2006). A common progenitor at the heart of development. Cell, 127, 1101–1004.
Ott, H. C., Matthiesen, T. S., Goh, S. K., Black, L. D., Kren, S. M., Netoff, T. I., et al. (2008). Perfusion-decellularized matrix: Using nature’s platform to engineer a bioartificial heart. Natural Medicines, 14(2), 213–221.
John, R., Liao, K., Lietz, K., Kamdar, F., Colvin-Adams, M., Boyle, A., et al. (2007). Experience with the Levitronix CentriMag circulatory support system as a bridge to decision in patients with refractory acute cardiogenic shock and multisystem organ failure. Journal of Thoracic and Cardiovascular Surgery, 134(2), 351–358.
Hall, J. L., Birks, E. J., Grindle, S., Cullen, M. E., Barton, P. J., Rider, J. E., et al. (2007). Molecular signature of recovery following combination left ventricular assist device (LVAD) support and pharmacologic therapy. European Heart Journal, 28(5), 613–627.
Acknowledgments
The Lillehei Heart Institute is supported in part by a gift from Katherine R. and + Dr. C. Walton Lillehei, ’41. Further support is acknowledged from the Fred C. and Katherine B. Andersen Foundation. The author acknowledges the support of Dean Deborah Powell, Dr. Frank Cerra, Dr. Roby C. Thompson and Dr. Charles Moldow.
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Garry, D.J. The Lillehei Heart Institute: Building on the Shoulders of Giants. J. of Cardiovasc. Trans. Res. 1, 273–277 (2008). https://doi.org/10.1007/s12265-008-9070-9
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DOI: https://doi.org/10.1007/s12265-008-9070-9