Abstract
Objective
To evaluate the effectiveness of an MRI-specific play therapy intervention on the need for sedation in young children.
Methods
All children in the age group of 4–10 y, who were advised an MRI scan over a period of one year were randomized. Exclusion criteria included children with neurodevelopmental disorders impairing cognition and children who had previously undergone diagnostic MRI. A total of 79 children were randomized to a control or an intervention condition. The intervention involved familiarizing the child with the MRI model machine, listing the steps involved in the scan to the child in vivid detail, training the child to stand still for 5 min, and conducting several dry runs with a doll or a favorite toy. The study was approved by the Institute ethical committee.
Results
The need for sedation was 41 % (n = 16) in the control group and this declined to 20 % (n = 8) in the intervention group (χ2 = 4.13; P = 0.04). The relative risk of sedation decreased by 49 % in the intervention group as compared to the control group (RR 0.49; 95 % CI: 0.24–1.01) and this difference was statistically significant (P = 0.04). The absolute risk difference in sedation use between intervention and control group was 21 % (95 % CI 1.3 %–40.8 %). Even on adjusting for age, relative risk of sedation remained significantly lower in children undergoing play therapy as compared to the control (RR 0.57, 95 % CI: 0.32–0.98) with P value of 0.04.
Conclusions
The use of an MRI customized play therapy with pediatric patients undergoing diagnostic MRI resulted in significant reduction of the use of sedation.
Similar content being viewed by others
References
Eshed I, Althoff CE, Hamm B, Hermann KG. Claustrophobia and premature termination of magnetic resonance imaging examinations. J Magn Reson Imaging. 2007;26:401–4.
Marshall SP, Smith MS, Weinberger E. Perceived anxiety of pediatric patients to magnetic resonance. Clin Pediatr. 1995;34:59–60.
Tyc VL, Fairclough D, Fletcher B, Leigh L, Mulhern RK. Children’s distress during magnetic resonance imaging procedures. Child Health Care. 1995;24:5–19.
Hallowell LM, Stewart SE, de Amorim e Silva CT, Ditchfield MR. Reviewing the process of preparing children for MRI. Pediatr Radiol. 2008;38:271–9.
Lukins R, Davan IG, Drummond PD. A cognitive behavioural approach to preventing anxiety during magnetic resonance imaging. J Behav Ther Exp Psychiatry. 1997;28:97–104.
Lawson GR. Sedation of children for magnetic resonance imaging. Arch Dis Child. 2000;82:150–4.
Green SM, Rothrock SG, Lynch EL, et al. Intramuscular ketamine for pediatric sedation in the emergency department: safety profile in 1,022 cases. Ann Emerg Med. 1998;31:688–97.
Malviya S, Voepel-Lewis T, Tait AR. Adverse events and risk factors associated with the sedation of children by non anaesthesiologists. Anaesth Analg. 1997;85:1207–13.
Cravero JP, Blike GT, Beach M, et al. Incidence and nature of adverse events during pediatric sedation/anesthesia for procedures outside the operating room: report from the Pediatric Sedation Research Consortium. Pediatrics. 2006;118:1087–96.
Cengiz M, Baysal Z, Ganidagli S. Oral sedation with midazolam and diphenhydramine compared with midazolam alone in children undergoing magnetic resonance imaging. Paediatr Anaesth. 2006;16:621–6.
Iwata S, Okumura A, Kato T, Itomi K, Kuno K. Efficacy and adverse effects of rectal thiamylal with oral triclofos for children undergoing magnetic resonance imaging. Brain Dev. 2006;28:175–7.
Sury MRJ, Hatch DJ, Deeley T, Dicks-Mireaux C, Chong WK. Development of a nurse-led sedation service for paediatric magnetic resonance imaging. Lancet. 1999;353:1667–71.
Hollman GA, Elderbrook MK, VanDenLagenberg B. Results of a pediatric sedation program on head MRI scan success rates and procedure duration times. Clin Pediatr. 1995;34:300–5.
Armstrong TS, Aitken HL. The developing role of play preparation in paediatric anaesthesia. Paediatr Anaesth. 2000;10:1–4.
Pressdee D, May L, Eastman E, Grier D. The use of play therapy in the preparation of children undergoing MR imaging. Clin Radiol. 1997;52:945–7.
Byars AW, Holland SK, Strawsburg RH, et al. Practical aspects of conducting large-scale functional magnetic resonance imaging studies in children. J Child Neurol. 2002;17:885–90.
Slifer KJ, Koontz KL, Cataldo MF. Operant-contingency-based preparation of children for functional magnetic resonance imaging. J Appl Behav Anal. 2002;35:191–4.
Rosenberg DR, Sweeney JA, Gillen JS, et al. Magnetic resonance imaging of children without sedation: preparation with simulation. J Am Acad Child Adolesc Psychiatry. 1997;36:853–9.
Nordahl C, Simon T, Zierhut C, et al. Brief report: methods for acquiring structural MRI data in very young children with autism without the use of sedation. J Autism Dev Disord. 2008;38:1581–90.
Koch BL. Avoiding sedation in pediatric radiology. Pediatr Radiol. 2008;38:S225–6.
Cejda K, Smeltzer M, Hansbury E, et al. The impact of preparation and support procedures for children with sickle cell disease undergoing MRI. Pediatr Radiol. 2012;42:1223–8.
de Amorim e Silva CJT, Mackenzie A, Hallowell LM, Stewart SE, Ditchfield MR. Practice MRI: reducing the need for sedation and general anaesthesia in children undergoing MRI. Australas Radiol. 2006;50:319–23.
Epstein JN, Casey BJ, Tonev ST, et al. Assessment and prevention of head motion during imaging of patients with attention deficit hyperactivity disorder. Psychiatry Res. 2007;155:75–82.
De Bie HM, Boersma M, Wattjes MP, et al. Preparing children with a mock scanner training protocol results in high quality structural and functional MRI scans. Eur J Pediatr. 2010;169:1079–85.
Carter AJ, Greer ML, Gray SE, et al. Mock MRI: Reducing the need for anaesthesia in children. Pediatr Radiol. 2010;40:1368–74.
Barnea-Goraly N, Weinzimer SA, Reisset AL. High success rates of sedation-free brain MRI scanning in young children using simple subject preparation protocols with and without a commercial mock scanner–the diabetes research in children network (direcnet) experience. Pediatr Radiol. 2014;44:181–6.
Acknowledgements
The authors acknowledge the help of their medical social worker Miss Suman Gautam who helped in preparing these children for the MRI.
Contributions
All the three authors assisted in contribution of the design of the study. BB and PM drafted the manuscript. PM will act as guarantor for this paper.
Conflict of Interest
None.
Source of Funding
Postgraduate Institute of Medical Education & Research Project.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Bharti, B., Malhi, P. & Khandelwal, N. MRI Customized Play Therapy in Children Reduces the Need for Sedation - A Randomized Controlled Trial. Indian J Pediatr 83, 209–213 (2016). https://doi.org/10.1007/s12098-015-1917-x
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s12098-015-1917-x