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The Charles Bonnet Syndrome: a Systematic Review of Diagnostic Criteria

  • Neurologic Ophthalmology and Otology (R Shin and D Gold, Section Editors)
  • Published:
Current Treatment Options in Neurology Aims and scope Submit manuscript

A Correction to this article was published on 04 October 2019

This article has been updated

Abstract

Purpose

To perform a systematic review of diagnostic criteria for the Charles Bonnet syndrome (CBS).

Recent findings

Across 33 studies that specified diagnostic criteria for CBS, hallucinations and vision loss were a common requirement, but there was considerable heterogeneity regarding hallucination properties (i.e., formed vs. unformed) and the severity of vision loss. The exclusion of confounding neuropsychiatric disorders was also common, but specific disorders and their method of ascertainment were variable.

Summary

There is considerable diagnostic heterogeneity for CBS in the literature. These differences have important implications for the results of observational and interventional studies of CBS and highlight the need for unified diagnostic criteria.

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Change history

  • 04 October 2019

    Shortly after publication, the authors became aware of several typographical errors in Table 1 which were introduced during the copy-editing process.

References and Recommended Reading

Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

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Authors and Affiliations

  1. Department of Neurology, Perelman School of Medicine, University of Pennsylvania, 3400 Spruce St., 3 W. Gates Bldg., Philadelphia, PA, 19104, USA

    Ali G. Hamedani MD MHS

  2. Departments of Neurology and Ophthalmology, The Rocky Mountain Lions Eye Institute, University of Colorado School of Medicine, Aurora, CO, USA

    Victoria S. Pelak MD

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Correspondence to Ali G. Hamedani MD MHS.

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The original version of this article was revised: Shortly after publication, the authors became aware of several typographical errors in Table 1 which were introduced during the copy-editing process.

This article is part of the Topical Collection on Neurologic Ophthalmology and Otology

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Hamedani, A.G., Pelak, V.S. The Charles Bonnet Syndrome: a Systematic Review of Diagnostic Criteria. Curr Treat Options Neurol 21, 41 (2019). https://doi.org/10.1007/s11940-019-0582-1

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