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Depression and apathy in Parkinson’s disease

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Abstract

This article provides an update on depression and apathy in Parkinson’s disease (PD), both of which are common but often misunderstood. The diagnosis of depression in PD can be challenging and we still do not have solid evidence on which to base our treatment decisions. Apathy is most commonly seen in the setting of dementia or depression but emerging evidence suggests that it may be a core feature of PD. There are conflicting reports about the effects of deep brain stimulation (DBS) on mood and apathy, but studies suggest that at least some patients may develop depression and apathy after the procedure. Although we are making strides toward a better understanding of depression and apathy in PD, it is clear that more research is needed about these non-motor features.

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Authors and Affiliations

  1. Department of Neurology, University of Rochester School of Medicine, Mt. Hope Professional Building, 1351 Mt. Hope Avenue, Suite 100, Rochester, NY, 14620-3917, USA

    Irene Hegeman Richard MD

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  1. Irene Hegeman Richard MD
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Correspondence to Irene Hegeman Richard MD.

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Richard, I.H. Depression and apathy in Parkinson’s disease. Curr Neurol Neurosci Rep 7, 295–301 (2007). https://doi.org/10.1007/s11910-007-0045-z

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  • DOI: https://doi.org/10.1007/s11910-007-0045-z

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