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Epidemiology of fracture in the Russian Federation and the development of a FRAX model

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Abstract

Summary

The incidence of hip, forearm and humeral fractures was studied in two cities from the Russian Federation. Fracture rates were used to create a FRAX model for Russia and to estimate the current and future burden of fracture.

Purpose

There is scant information on the epidemiology of fracture in Russia. The aim of the study was to determine the incidence of major fractures in order to populate a new FRAX model and to characterise the burden and future burden of fractures.

Methods

The number of hip, forearm and humeral fractures was determined in two Russian cities with a well-defined catchment population over a 2–3-year period. Incidence rates for the two cities were merged and used to populate a FRAX model for Russia. Incidence rates were also applied to the general population in 2010 and 25 years later in 2035.

Results

A total of 6,012 fractures were documented. For hip fracture, 27 % of cases in Pervouralsk and 1.8 % in Yaroslavl were not registered in the hospital data base. The incidence of index fractures increased with age and was higher in women than in men. The lifetime probability of hip fracture at the age of 50 years was 4 % in men and 7 % in women. The total number of hip fractures estimated in 2010 (112,000) is expected to rise to 159,000 in 2035. The estimated number of major fractures will rise from 590,000 to 730,000 over the same time interval.

Conclusions

Fragility fractures pose a serious health care problem in Russia. Urgent steps are needed to improve the acute management of hip fracture and long-term care of other osteoporotic fractures.

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Authors and Affiliations

  1. Department of Family Medicine, Ural State Medical Academy, 185, Volgogradskaya Street, Yekaterinburg, 620102, Russian Federation

    Olga Lesnyak, Elena Gladkova & Vitalij Khodirev

  2. Department of Internal Diseases, Yaroslavl State Medical Academy, 11, Zagorodnij sad street, Yaroslavl, 150003, Russian Federation

    Olga Ershova, Ksenia Belova, Olga Sinitsina, Olga Ganert & Marina Romanova

  3. WHO Collaborating Centre for Metabolic Bone Diseases, University of Sheffield Medical School, Beech Hill Road, Sheffield, S10 2RX, UK

    Helena Johansson, Eugene McCloskey & John A Kanis

Authors
  1. Olga Lesnyak
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  2. Olga Ershova
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  3. Ksenia Belova
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  4. Elena Gladkova
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  5. Olga Sinitsina
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  6. Olga Ganert
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  7. Marina Romanova
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  8. Vitalij Khodirev
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  9. Helena Johansson
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  10. Eugene McCloskey
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  11. John A Kanis
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Correspondence to Olga Lesnyak or John A Kanis.

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Lesnyak, O., Ershova, O., Belova, K. et al. Epidemiology of fracture in the Russian Federation and the development of a FRAX model. Arch Osteoporos 7, 67–73 (2012). https://doi.org/10.1007/s11657-012-0082-3

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  • DOI: https://doi.org/10.1007/s11657-012-0082-3

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