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Functional outcomes of sleep in Thai patients with obstructive sleep-disordered breathing

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Abstract

Purposes

Quality of life assessment in obstructive sleep-disordered breathing (OSDB) is increasingly recognized, and the functional outcomes of sleep questionnaire (FOSQ) is a popular instrument. The objective of this study was to apply this questionnaire in Thai patients to assess its reliability, validity, and responsiveness properties.

Methods

A total of 223 subjects were recruited. The scores of FOSQ in 38 healthy volunteers and 40 primary snorers were compared with those of 108 obstructive sleep apnea (OSA) patients diagnosed by polysomnography. Seventy-two subjects answered the FOSQ twice at 2–4 weeks apart to check the test–retest reliability, and 37 patients with OSA who complied well with CPAP therapy answered them again after treatment at 3–6 months. All participants also filled the Epworth sleepiness scales (ESS) to check the concurrent validity.

Results

There were statistically significant differences in all FOSQ subscales including global scores between healthy volunteers (17.3 ± 2.1) and OSA patients (14.5 ± 2.9) (p < 0.001). The internal consistency of the questionnaire was excellent (Cronbach's alpha 0.95), and the test–retest reliability (intra-class correlation coefficients) was 0.70 in global scores. After adequate CPAP therapy, all FOSQ scores increased significantly (p < 0.001) There were significant correlations between all FOSQ scores except sexual relationship and ESS (r −0.48); however, these had only a weak relationship with AHI and minimal oxygen saturation.

Conclusions

The FOSQ can be applied to Thai patients with OSDB with good reliability, validity, and responsiveness properties. It may be the first validated version of FOSQ in East Asian countries which is a very useful tool for future research.

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Acknowledgments

This study was supported by the Faculty of Medicine, Siriraj Hospital, Mahidol University, Thailand. We are grateful to Professor Terri E. Weaver for her kindness in giving permission for translation of the FOSQ into Thai language and for her valuable advice for our research. We appreciate Dr. Chulaluck Komoltree for her comprehensive statistical analysis and Professor Narong Simakajornboon, Professor Niphon Puangvarin, Professor Arth Nana, Associate Professor Nitipat Chierakul, and Dr. Pimon Rattanaumpawan for their advice and a good coordination of the research. We also thank all nurses and staffs of the ENT Department and Siriraj Sleep Center who participated in this study. Finally, we would like to thank all patients who dedicated their time to follow through with and complete our project.

Conflicts of interest

The authors declare that they have no conflict of interest.

Author information

Authors and Affiliations

  1. The Department of Otorhinolaryngology, Faculty of Medicine, Siriraj Hospital, Mahidol University, 2 Phrannok Rd, Bangkoknoi, Bangkok, Thailand, 10700

    Wish Banhiran, Paraya Assanasen, Choakchai Metheetrairut & Jeerapa Kerdnoppakhun

  2. The Department of Medicine, Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, Thailand

    Cherdchai Nopmaneejumruslers & Wattanachai Chotinaiwattarakul

Authors
  1. Wish Banhiran
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  2. Paraya Assanasen
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  3. Choakchai Metheetrairut
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  4. Cherdchai Nopmaneejumruslers
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  5. Wattanachai Chotinaiwattarakul
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  6. Jeerapa Kerdnoppakhun
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Corresponding author

Correspondence to Wish Banhiran.

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Banhiran, W., Assanasen, P., Metheetrairut, C. et al. Functional outcomes of sleep in Thai patients with obstructive sleep-disordered breathing. Sleep Breath 16, 663–675 (2012). https://doi.org/10.1007/s11325-011-0556-3

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  • DOI: https://doi.org/10.1007/s11325-011-0556-3

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