Skip to main content

Advertisement

SpringerLink
Log in

Predicting technique and patient survival over 12 months in peritoneal dialysis: the role of anxiety and depression

  • Nephrology - Original Paper
  • Published:
International Urology and Nephrology Aims and scope Submit manuscript

An Erratum to this article was published on 11 March 2016

Abstract

Background

Emotional distress is common in dialysis patients, but its role on clinical outcomes for patients on peritoneal dialysis (PD) is uncertain.

Purpose

To evaluate the effect of depression and anxiety on 1-year prognosis in PD patients.

Methods

A total of N = 201 PD patients (58.9 ± 12.59 years) completed the Hospital Anxiety Depression Scale and measures of social support at baseline and were followed up for CC technique and actuarial patient survival.

Results

Mortality and technique failure rates were 9.9 and 5.97 %, respectively. Carer-assisted PD, anxiety, comorbid burden and albumin were significant univariate predictors. Multivariate proportional hazard model to adjust for confounders indicated that anxiety remained significant with HR of 2.145 [95 % CI 1.03, 4.49, p = 0.043] for death/technique failure.

Conclusion

Anxiety is an important predictor of actuarial and technique survival in PD. Effective treatment for symptoms of anxiety may represent an easily achievable means of improving the clinical outcome of PD patients.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. Jiwakanon S, Chiu YW, Kalantar-Zadeh K, Mehrotra R (2010) Peritoneal dialysis: an underutilized modality. Curr Opin Nephrol Hypertens 19(6):573–577

    Article  PubMed  Google Scholar 

  2. Tam P (2009) Peritoneal dialysis and preservation of residual renal function. Perit Dial Int 2(2):S108–S110

    Google Scholar 

  3. Klarenbach S, Manns B (2009) Economic evaluation of dialysis therapies. Semin Nephrol 29(5):524–532

    Article  PubMed  Google Scholar 

  4. Griva K, Kang AWC, Yu ZL et al (2014) Quality of life and emotional distress between patients on peritoneal dialysis versus community-based hemodialysis. Qual Life Res 23(1):57–66

    Article  CAS  PubMed  Google Scholar 

  5. Chilcot J, Wellsted D, Farrington K (2009) Depression in end-stage renal disease: current advances and research. Semin Dial 23:74–82

    Article  PubMed  Google Scholar 

  6. Cukor D, Ver Halen N, Fruchter Y (2013) Anxiety and quality of life in ESRD. Semin Dial 26(3):265–268

    Article  PubMed  Google Scholar 

  7. Davies SJ, Russell L, Bryan J, Phillips L, Russell GI (1995) Comorbidity, urea kinetics, and appetite in continuous ambulatory peritoneal dialysis patients: their interrelationship and prediction of survival. Am J Kidney Dis 26:353–361

    Article  CAS  PubMed  Google Scholar 

  8. Jager KJ, Merkus MP, Dekker FW et al (1999) Mortality and technique failure in patients starting chronic peritoneal dialysis: results of the Netherlands Cooperative Study on the Adequacy of Dialysis. NECOSAD Study Group. Kidney Int 55:1476–1485

    Article  CAS  PubMed  Google Scholar 

  9. Stenvinkel P, Chung SH, Heimburger O, Lindholm B (2001) Malnutrition, inflammation, and atherosclerosis in peritoneal dialysis patients. Perit Dial Int 21(3):S157–S162

    PubMed  Google Scholar 

  10. Fan L, Sarnak MJ, Tighiouart H et al (2014) Depression and all-cause mortality in hemodialysis patients. Am J Nephrol 40(1):12–18

    Article  PubMed  PubMed Central  Google Scholar 

  11. Thong MS, Kaptein AA, Krediet RT, Boeschoten EW, Dekker FW (2007) Social support predicts survival in dialysis patients. Nephrol Dial Transplant 22(3):845–850

    Article  PubMed  Google Scholar 

  12. Zigmond AS, Snaith RP (1983) The hospital anxiety and depression scale. Acta Psychiatr Scand 67(6):361–370

    Article  CAS  PubMed  Google Scholar 

  13. Hays RD, Kallich JD, Mapes DL et al (1997) Kidney disease quality of life short form (KDQOL-SF ™). Version 1.3: a manual for use and scoring. Rand, Santa Monica

    Google Scholar 

  14. RAND Health. Kidney disease quality of life instrument (KDQOL). http://www.rand.org/health/surveys_tools/kdqol.html. Accessed 22nd November 2015

  15. Leung CM, Ho S, Kan CS, Hung CH, Chen CN (1993) Evaluation of the Chinese version of the hospital anxiety and depression scale: a cross-cultural perspective. Int J Psychosom 40(1–4):29–34

    CAS  PubMed  Google Scholar 

  16. Yusoff N, Low WY, Yip CH (2011) Psychometric properties of the Malay version of the hospital anxiety and depression scale: a study of husbands of breast cancer patients in Kuala Lumpur, Malaysia. Asian Pac J Cancer Prev 12(4):915–917

    PubMed  Google Scholar 

  17. Bjelland I, Dahl AA, Haug TT, Neckelmann D (2002) The validity of the hospital anxiety and depression scale: an updated literature review. J Psychosom Res 52(2):69–77

    Article  PubMed  Google Scholar 

  18. Loosman WL, Siegert CEH, Korzec A, Honig A (2010) Validity of the hospital anxiety and depression scale and the beck depression inventory for use in end-stage renal disease patients. Br J Clin Psychol 49(4):507–516

    Article  CAS  PubMed  Google Scholar 

  19. Preljevic VT, Østhus TBH, Sandvik L, Opjordsmoen S, Nordhus IH, Os I, Dammen T (2012) Screening for anxiety and depression in dialysis patients: comparison of the hospital anxiety and depression scale and the beck depression inventory. J Psychosom Res 73(2):139–144

    Article  PubMed  Google Scholar 

  20. Charlson ME, Pompei P, Ales KL, MacKenzie CR (1987) A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 40(5):373–383

    Article  CAS  PubMed  Google Scholar 

  21. Griva K, Davenport A, Harrison M, Newman S (2010) An evaluation of illness, treatment perceptions, and depression in hospital vs. home-based dialysis modalities. J Psychosom Res 69(4):363–370

    Article  PubMed  Google Scholar 

  22. Frasure-Smith N, Lesperance F, Talajic M (1995) The impact of negative emotions on prognosis following myocardial infarction: is it more than depression? Health Psychol 14:388–398

    Article  CAS  PubMed  Google Scholar 

  23. Thayer JF, Friedman BH, Borkovec TD (1996) Autonomic characteristics of generalized anxiety disorder and worry. Biol Psychiatry 39:255–266

    Article  CAS  PubMed  Google Scholar 

  24. Vlachojannis JG, Tsakas S, Alexandri S, Petropoulou C, Goumenos DS (2000) Continuous ambulatory peritoneal dialysis is responsible for an increase in plasma norepinephrine. Perit Dial Int 20:322–327

    CAS  PubMed  Google Scholar 

  25. Stefanidis I, Zarogiannis S, Hatzoglou C et al (2005) Enhancement of the transmesothelial resistance of the parietal sheep peritoneum by epinephrine in vitro: Ussing-type chamber experiments. Artif Organs 29(11):919–922

    Article  PubMed  Google Scholar 

Download references

Acknowledgments

We would like to thank all participants for their contribution to this study. This research was supported by grants from the Singapore Ministry of Education–National University of Singapore Academic Research Fund (Start-Up; FY2007-FRC5-006), which we gratefully acknowledge. Grant body had no role in study design, data collection, analyses, or interpretation, manuscript preparation, or the decision to submit the manuscript for publication.

Author information

Authors and Affiliations

  1. Department of Psychology, National University of Singapore, Block AS4, #02-28, 9 Arts Link, Singapore, 117570, Singapore

    Konstadina Griva, Augustine W. C. Kang, Zhen Li Yu & Vanessa Y. W. Lee

  2. Health Services Research Group, City University London, London, UK

    Konstadina Griva

  3. Department of Physiology, Faculty of Medicine, University of Thessaly, Karditsa, Greece

    Sotiris Zarogianis

  4. Department of Renal Medicine, Singapore General Hospital, Singapore, Singapore

    Moong Chen Chan & Marjorie Foo

Authors
  1. Konstadina Griva
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Augustine W. C. Kang
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Zhen Li Yu
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Vanessa Y. W. Lee
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Sotiris Zarogianis
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Moong Chen Chan
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Marjorie Foo
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Konstadina Griva.

Ethics declarations

Conflict of interest

The authors declare that they have no conflict of interest.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Griva, K., Kang, A.W.C., Yu, Z.L. et al. Predicting technique and patient survival over 12 months in peritoneal dialysis: the role of anxiety and depression. Int Urol Nephrol 48, 791–796 (2016). https://doi.org/10.1007/s11255-015-1191-x

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s11255-015-1191-x

Keywords

Search

Navigation