Skip to main content
Mijn bibliotheek
Shop
Nieuws Boeken Tijdschriften E-learning Web-tv Video Audio
Tips voor Mijn BSL
UITGEBREID ZOEKEN
Inloggen
Top
Quality of Life Research
Gepubliceerd in: Quality of Life Research 6/2020

Open Access 07-01-2020

Social inequalities in health-related quality of life among people aging with HIV/AIDS: the role of comorbidities and disease severity

Auteurs: Jochen Drewes, Jennifer Ebert, Phil C. Langer, Dieter Kleiber, Burkhard Gusy

Gepubliceerd in: Quality of Life Research | Uitgave 6/2020

Log in om toegang te krijgen
share
DELEN

Deel dit onderdeel of sectie (kopieer de link)

  • Optie A:
    Klik op de rechtermuisknop op de link en selecteer de optie “linkadres kopiëren”
  • Optie B:
    Deel de link per e-mail
    Link delen
publish
Publiceer nu

Abstract

Purpose

While socioeconomic inequalities in health-related quality of life are well documented in the scientific literature, research has neglected to look into the reasons for these inequalities. The purpose of this study is to determine in what way social inequalities in health-related quality of life among patients with the same chronic disease could be explained by variations in disease severity.

Methods

We used the data of 748 people aging with HIV in Germany who took part in the nationwide study 50plushiv and provided self-report data on socioeconomic status, health-related quality of life (SF-12) and various markers of disease severity (comorbidity, falls, late presentation and AIDS diagnosis). Regression analyses were applied to determine the impact of SES on HRQOL after adjusting for disease severity variables.

Results

The mental and physical subscales of the SF-12, comorbidity burden and falls were significantly related to SES. SES explained 7% of the variance in PCS scores and 3% of the variance in MCS scores after adjusting for age and time since diagnosis. Markers of disease severity explained 33% of the variance in PCS scores and 14% of the variance in MCS scores. After adjusting for disease severity SES was still significantly related to PCS and MCS scores.

Conclusions

The diverse sample of people aging with HIV showed social inequalities regarding HRQOL and most of the disease severity markers. SES was significantly related to mental and physical HRQOL after adjusting for disease severity. Possible explanations for this phenomenon are discussed.
vorige artikel The relationship between frequency and severity of vaso-occlusive crises and health-related quality of life and work productivity in adults with sickle cell disease
volgende artikel Health-related quality of life (HRQoL) associated with echinococcosis patients in Tibetan communities in Shiqu County, China: a case–control study
Literatuur
1.
Lubetkin, E. I., Jia, H., Franks, P., & Gold, M. R. (2005). Relationship among sociodemographic factors, clinical conditions, and health-related quality of life: examining the EQ-5D in the US general population. Quality of Life Research,14(10), 2187–2196.PubMed
2.
Worthington, C., & Krentz, H. B. (2005). Socio-economic factors and health-related quality of life in adults living with HIV. International journal of STD & AIDS,16(9), 608–614.
3.
Stafford, M., Soljak, M., Pledge, V., & Mindell, J. (2012). Socio-economic differences in the health-related quality of life impact of cardiovascular conditions. European Journal of Public Health,22(3), 301–305.PubMed
4.
Von Rueden, U., Gosch, A., Rajmil, L., Bisegger, C., & Ravens-Sieberer, U. (2006). Socioeconomic determinants of health related quality of life in childhood and adolescence: Results from a European study. Journal of Epidemiology and Community Health,60(2), 130–135.
5.
Liu, C., Johnson, L., Ostrow, D., Silvestre, A., Visscher, B., & Jacobson, L. P. (2006). Predictors for lower quality of life in the HAART era among HIV-infected men. JAIDS Journal of Acquired Immune Deficiency Syndromes,42(4), 470–477.PubMed
6.
Ross, N. A., Garner, R., Bernier, J., Feeny, D. H., Kaplan, M. S., McFarland, B., et al. (2012). Trajectories of health-related quality of life by socio-economic status in a nationally representative Canadian cohort. Journal of Epidemiology and Community Health,66(7), 593–598.PubMed
7.
Mielck, A., Vogelmann, M., & Leidl, R. (2014). Health-related quality of life and socioeconomic status: inequalities among adults with a chronic disease. Health and Quality of Life Outcomes,12(1), 1.
8.
Vidrine, D. J., Amick, B. C., Gritz, E. R., & Arduino, R. C. (2005). Assessing a conceptual framework of health-related quality of life in a HIV/AIDS population. Quality of Life Research,14(4), 923–933.PubMed
9.
10.
Jung, S., Lee, S. M., Suh, D., Shin, H. T., & Suh, D. C. (2018). The association of socioeconomic and clinical characteristics with health-related quality of life in patients with psoriasis: A cross-sectional study. Health and Quality of Life Outcomes,16(1), 180.PubMedPubMedCentral
11.
Sprangers, M. A. G., de Regt, E. B., Andries, F., van Agt, H. M. E., Bijl, R. V., de Boer, J. B., et al. (2000). Which chronic conditions are associated with better or poorer quality of life? Journal of Clinical Epidemiology,53(9), 895–907.PubMed
12.
Ferrucci, L., Baldasseroni, S., Bandinelli, S., De Alfieri, W., Cartei, A., Calvani, D., et al. (2000). Disease severity and health-related quality of life across different chronic conditions. Journal of the American Geriatrics Society,48(11), 1490–1495.PubMed
13.
Ståhl, E., Lindberg, A., Jansson, S. A., Rönmark, E., Svensson, K., Andersson, F., et al. (2005). Health-related quality of life is related to COPD disease severity. Health and Quality of Life Outcomes,3(1), 56.PubMedPubMedCentral
14.
Bernfort, L., Gerdle, B., Rahmqvist, M., Husberg, M., & Levin, L. Å. (2015). Severity of chronic pain in an elderly population in Sweden—Impact on costs and quality of life. Pain,156(3), 521–527.PubMed
15.
Lorenz, K. A., Cunningham, W. E., Spritzer, K. L., & Hays, R. D. (2006). Changes in symptoms and health-related quality of life in a nationally representative sample of adults in treatment for HIV. Quality of Life Research,15(6), 951–958.PubMed
16.
17.
Bachmann, M. O., Eachus, J., Hopper, C. D., Davey Smith, G., Propper, C., Pearson, N. J., et al. (2003). Socio-economic inequalities in diabetes complications, control, attitudes and health service use: A cross-sectional study. Diabetic Medicine,20(11), 921–929.PubMed
18.
Eachus, J., Chan, P., Pearson, N., Propper, C., & Smith, G. D. (1999). An additional dimension to health inequalities: Disease severity and socioeconomic position. Journal of Epidemiology and Community Health,53(10), 603–611.PubMedPubMedCentral
19.
Brekke, M., Hjortdahl, P., & Kvien, T. K. (2002). Severity of musculoskeletal pain: Relations to socioeconomic inequality. Social Science & Medicine,54(2), 221–228.
20.
21.
Klein, J., Hofreuter-Gätgens, K., Lüdecke, D., Fisch, M., Graefen, M., & von dem Knesebeck, O. (2016). Socioeconomic status and health-related quality of life among patients with prostate cancer 6 months after radical prostatectomy: A longitudinal analysis. British Medical Journal Open,6(6), e010968.
22.
Bhavan, K. P., Kampalath, V. N., & Overton, E. T. (2008). The aging of the HIV epidemic. Current HIV/AIDS Reports,5(3), 150–158.PubMed
23.
Balderson, B. H., Grothaus, L., Harrison, R. G., McCoy, K., Mahoney, C., & Catz, S. (2013). Chronic illness burden and quality of life in an aging HIV population. AIDS Care,25(4), 451–458.PubMed
24.
Rodriguez-Penney, A. T., Iudicello, J. E., Riggs, P. K., Doyle, K., Ellis, R. J., Letendre, S. L., et al. (2013). Co-morbidities in persons infected with HIV: Increased burden with older age and negative effects on health-related quality of life. AIDS Patient Care and STDs,27(1), 5–16.PubMedPubMedCentral
25.
Miners, A., Phillips, A., Kreif, N., Rodger, A., Speakman, A., Fisher, M., et al. (2014). Health-related quality-of-life of people with HIV in the era of combination antiretroviral treatment: A cross-sectional comparison with the general population. The Lancet HIV,1(1), e32–e40.PubMed
26.
Engelhard, E. A., Smit, C., Van Dijk, P. R., Kuijper, T. M., Wermeling, P. R., Weel, A. E., et al. (2018). Health-related quality of life of people with HIV: An assessment of patient related factors and comparison with other chronic diseases. Aids,32(1), 103–112.PubMed
27.
Campsmith, M. L., Nakashima, A. K., & Davidson, A. J. (2003). Self-reported health-related quality of life in persons with HIV infection: Results from a multi-site interview project. Health and Quality of Life Outcomes,1(1), 12.PubMedPubMedCentral
28.
Sankar, A., Nevedal, A., Neufeld, S., Berry, R., & Luborsky, M. (2011). What do we know about older adults and HIV? A review of social and behavioral literature. AIDS Care,23, 1187–1207.PubMedPubMedCentral
29.
Antinori, A., Coenen, T., Costagiola, D., Dedes, N., Ellefson, M., Gatell, J., et al. (2011). Late presentation of HIV infection: A consensus definition. HIV Medicine,12(1), 61–64.PubMed
30.
Ward, M., Buehler, M. J. W., Jaffe, M. H. W., & Berkelman, R. L. (1992). 1993 revised classification system for HIV infection and expanded surveillance case definition for AIDS among adolescents and adults. MMWR Recommendations and Reports,41, 1–19.
31.
Inouye, S. K., Studenski, S., Tinetti, M. E., & Kuchel, G. A. (2007). Geriatric syndromes: Clinical, research, and policy implications of a core geriatric concept. Journal of the American Geriatrics Society,55(5), 780–791.PubMedPubMedCentral
32.
Lampert, T., Kroll, L., Müters, S., & Stolzenberg, H. (2013). Messung des sozioökonomischen Status in der Studie zur Gesundheit Erwachsener in Deutschland (DEGS1). Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz,56(5/6), 631–636.PubMed
33.
Morfeld, M., Kirchberger, I, & Bullinger, M. (2011). SF-36. Fragebogen zum Gesundheitszustand (2., ergänzte und überarbeitete Auflage). Göttingen: Hogrefe.
34.
Drewes, J., Gusy, B., & von Rüden, U. (2013). More than 20 years of research into the quality of life of people with HIV and AIDS—A descriptive review of study characteristics and methodological approaches of published empirical studies. Journal of the International Association of Providers in AIDS Care,12, 18–22.
35.
Gandek, B., Ware, J. E., Aaronson, N. K., Apolone, G., Bjorner, J. B., Brazier, J. E., et al. (1998). Cross-validation of item selection and scoring for the SF-12 health survey in nine countries: Results from the IQOLA Project. Journal of Clinical Epidemiology,51(11), 1171–1178.PubMed
36.
Apter, A. J., Reisine, S. T., Affleck, G., Barrows, E., & ZuWallack, R. L. (1999). The influence of demographic and socioeconomic factors on health-related quality of life in asthma. Journal of Allergy and Clinical Immunology,103(1), 72–78.PubMed
37.
Teresi, J. A., & Fleishman, J. A. (2007). Differential item functioning and health assessment. Quality of Life Research,16(1), 33–42.PubMed
38.
Sprangers, M. A., & Schwartz, C. E. (1999). Integrating response shift into health-related quality of life research: A theoretical model. Social Science & Medicine,48(11), 1507–1515.
39.
Rapkin, B. D., & Schwartz, C. E. (2004). Toward a theoretical model of quality-of-life appraisal: Implications of findings from studies of response shift. Health and Quality of Life Outcomes,2(1), 14.PubMedPubMedCentral
40.
Rapkin, B. D., & Schwartz, C. E. (2019). Advancing quality-of-life research by deepening our understanding of response shift: A unifying theory of appraisal. Journal of Quality of Life Research,28(10), 2623–2630.
41.
Rapkin, B. D., Garcia, I., Michael, W., Zhang, J., & Schwartz, C. E. (2018). Development of a practical outcome measure to account for individual differences in quality-of-life appraisal: The Brief Appraisal Inventory. Quality of Life Research,27(3), 823–833.PubMed
42.
Almeida, D. M., Neupert, S. D., Banks, S. R., & Serido, J. (2005). Do daily stress processes account for socioeconomic health disparities? The Journals of Gerontology Series B: Psychological Sciences and Social Sciences,60(Special_Issue_2), S34–S39.
43.
Braveman, P. A., Cubbin, C., Egerter, S., Chideya, S., Marchi, K. S., Metzler, M., et al. (2005). Socioeconomic status in health research: One size does not fit all. Journal of the American Medical Association,294(22), 2879–2888.PubMed
44.
Strandhagen, E., Berg, C., Lissner, L., Nunez, L., Rosengren, A., Torén, K., et al. (2010). Selection bias in a population survey with registry linkage: Potential effect on socioeconomic gradient in cardiovascular risk. European Journal of Epidemiology,25(3), 163–172.PubMed
45.
De-loyde, K. J., Harrison, J. D., Durcinoska, I., Shepherd, H. L., Solomon, M. J., & Young, J. M. (2015). Which information source is best? Concordance between patient report, clinician report and medical records of patient co-morbidity and adjuvant therapy health information. Journal of Evaluation in Clinical Practice, 21(2), 339–346.PubMed
Metagegevens
Titel
Social inequalities in health-related quality of life among people aging with HIV/AIDS: the role of comorbidities and disease severity
Auteurs
Jochen Drewes
Jennifer Ebert
Phil C. Langer
Dieter Kleiber
Burkhard Gusy
Publicatiedatum
07-01-2020
Uitgeverij
Springer International Publishing
Gepubliceerd in
Quality of Life Research / Uitgave 6/2020
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-020-02413-9

Andere artikelen Uitgave 6/2020

Quality of Life Research 6/2020 Naar de uitgave

Review

Capability instruments in economic evaluations of health-related interventions: a comparative review of the literature

OriginalPaper

A bi-directional association between weight change and health-related quality of life: evidence from the 11-year follow-up of 9916 community-dwelling adults

OriginalPaper

Modelling a preference-based index for EQ-5D-3L and EQ-5D-3L + Sleep using a Bayesian framework

OriginalPaper

Qualitative study of patients with venous malformations: symptom experiences and content validity of patient-reported outcome measures

OriginalPaper

Health-related quality of life (HRQoL) associated with echinococcosis patients in Tibetan communities in Shiqu County, China: a case–control study

OriginalPaper

Oral health-related quality of life of patients after heart transplantation and those with heart failure is associated with general health-related quality of life: a cross-sectional study