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Gepubliceerd in:

22-01-2018

Longitudinal study of quality of life among children with acute respiratory infection and cough

Auteurs: Yolanda G. Lovie-Toon, Anne B. Chang, Peter A. Newcombe, Dimitrios Vagenas, Sophie Anderson-James, Benjamin J. Drescher, Michael E. Otim, Kerry-Ann F. O’Grady

Gepubliceerd in: Quality of Life Research | Uitgave 4/2018

Abstract

Purpose

Acute respiratory infections (ARIs), and associated symptoms such as cough, are frequently experienced among children and impose a burden on families (e.g., use of medical resources and time off work/school). However, there are little data on changes in, and predictors of, quality of life (QoL) over the duration of an ARI with cough (ARIwC) episode. We therefore aimed to determine cough-specific QoL and identify its influencing factors among children with ARIwC, at the time of presentation to a pediatric emergency department (ED), and over the following 4 weeks.

Methods

Data from 283 children aged < 15 years were included in our analyses. We used the validated parent-proxy children’s acute cough-specific QoL questionnaire (PAC-QoL) at each time-point. Linear regression and mixed effect modeling were used to identify factors influencing QoL at baseline and over the follow-up period.

Results

Median PAC-QoL at baseline was 2.7 (IQR 2.1–3.6) and significantly improved by Day-7 (4.9, IQR 3.8–6.1) and Day-14 (6.59, IQR 5.1–7.0), both p < 0.001. The improvements in median PAC-QoL between Days-14, -21, and -28 were not significant. Regression modeling identified that day-cough severity, night-cough severity, and financial concerns had the highest impact on both baseline, and follow-up, PAC-QoL scores. There were five additional independent significant factors at baseline and six at follow-up.

Conclusions

Quality of life is considerably impaired at presentation to ED, but improves significantly by Days-7 and -14. As cough severity and financial concerns had the highest impact on QoL, effectively managing cough to reduce the clinical and financial burden on children and families is important.

vorige artikel Predictors of self-reported health-related quality of life according to the EQ-5D-Y in chronically ill children and adolescents with asthma, diabetes, and juvenile arthritis: longitudinal results

volgende artikel Association between secondhand smoke exposure and quality of life in pregnant women and postpartum women and the consequences on the newborns

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Titel: Longitudinal study of quality of life among children with acute respiratory infection and cough
Auteurs: Yolanda G. Lovie-Toon
Anne B. Chang
Peter A. Newcombe
Dimitrios Vagenas
Sophie Anderson-James
Benjamin J. Drescher
Michael E. Otim
Kerry-Ann F. O’Grady
Publicatiedatum: 22-01-2018
Uitgeverij: Springer International Publishing
Gepubliceerd in: Quality of Life Research / Uitgave 4/2018
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI: https://doi.org/10.1007/s11136-017-1779-y

Bohn Stafleu van Loghum

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Abstract

Purpose

Methods

Results

Conclusions

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