Introduction
Methods
Subjects and study design
Assessments
Definition of end-points
Statistical analyses
Results
All | |
---|---|
n = 213 | |
Socio-demographic data | |
Age | 46.5 (11) |
Gender, men (%) | 50 |
Married or cohabiting, % | 74 |
High school/university, % | 28 |
Employed, % | 62 |
Long-term sick leave/disabled, % | 32 |
Daily smoker, % | 25 |
Weight measures | |
Weight, kg | 112.2 (22) |
Body mass index, kg/m2
| 36.8 (6.0) |
Waist circumference, cm | 119 (14) |
Diet | |
Healthy diet, % | 1 |
Somewhat unhealthy diet, % | 39 |
Unhealthy diet, % | 60 |
Aerobic capacity, ml/kg/min (n = 201) | 26.8 (7.6) |
Good, excellent or superior aerobic capacity, % | 25 |
Poor or very poor aerobic capacity, % | 55 |
SF-36 domain* | All | Norm # | Completers | Dropouts |
---|---|---|---|---|
n = 212 |
n = 4,444 |
n = 182 |
n = 30 | |
Bodily pain (BP) | 60 (29) | 75 (25)*** | 62 (28) | 46 (31)** |
General health (GH) | 58 (24) | 77 (21)*** | 60 (24) | 42 (22)*** |
Physical function (PF) | 75 (20) | 90 (17)*** | 77 (19) | 63 (21)*** |
Physical role limitation (RP) | 64 (41) | 82 (34)*** | 66 (40) | 49 (42)* |
Mental health (MH) | 74 (18) | 80 (15)*** | 76 (17) | 64 (23)** |
Social function (SF) | 79 (26) | 87 (20)*** | 81 (24) | 65 (31)** |
Vitality (VT) | 47 (23) | 61 (20)*** | 49 (22) | 37 (23)** |
Emotional role limitation (RE) | 76 (37) | 87 (29)*** | 79 (36) | 55 (41)** |
Physical component summary (PCS) | 41 (12) | 50 (10)*** | 42 (12) | 36 (11)* |
Mental component summary (MCS) | 47 (13) | 50 (10)*** | 48 (12) | 41 (15)* |
SF-36 domain* | All | Not achieving both goals | Achieving both goals |
---|---|---|---|
n = 172 |
n = 96 |
n = 26 | |
Bodily pain (BP) | 0 (25) | −2 (22) | 13 (29)* |
General health (GH) | 4 (18) | 2 (17) | 14 (16)** |
Physical function (PF) | 5 (16) | 5 (13) | 17 (15)*** |
Physical role limitation (RP) | 0 (40) | 1 (37) | 15 (42) |
Mental health (MH) | 2 (18) | 2 (16) | 7 (16) |
Social function (SF) | 3 (25) | 0 (21) | 14 (24)** |
Vitality (VT) | 5 (22) | 3 (22) | 17 (16)** |
Emotional role limitation (RE) | 3 (39) | 6 (30) | 3 (38) |
Physical component summary (PCS) | 2 (9) | 1 (8) | 8 (9)*** |
Mental component summary (MCS) | 1 (13) | 1 (11) | 4 (11) |
SF-36 domain* | Baseline | 6 months | 6 months | 18 months | Baseline | 18 months |
---|---|---|---|---|---|---|
n = 166 |
n = 166 |
n = 150 |
n = 150 |
n = 172 |
n = 172 | |
Bodily pain (BP) | 62 (27) | 62 (27) | 63 (27) | 62 (29) | 62 (28) | 62 (30) |
General health (GH) |
60 (23)
|
64 (23)*
| 64 (23) | 64 (23) |
59 (24)
|
64 (23)**
|
Physical function (PF) |
78 (18)
|
80 (18)**
| 81 (17) | 82 (17) |
76 (19)
|
81 (18)***
|
Physical role limitation (RP) |
65 (40)
|
71 (38)*
|
73 (37)
|
65 (40)**
| 65 (40) | 65 (41) |
Mental health (MH) | 76 (17) | 77 (17) | 78 (16) | 77 (18) | 76 (17) | 78 (17) |
Social function (SF) | 81 (25) | 84 (23) | 84 (22) | 83 (23) | 80 (25) | 83 (23) |
Vitality (VT) |
49 (21)
|
53 (22)*
| 53 (22) | 52 (24) |
48 (22)
|
53 (23)**
|
Emotional role limitation (RE) | 79 (36) | 84 (31) | 85 (30) | 81 (35) | 79 (36) | 81 (34) |
Physical component summary (PCS) |
42 (11)
|
44 (11)*
| 44 (11) | 44 (11) |
42 (12)
|
44 (12)*
|
Mental component summary (MCS) | 48 (13) | 50 (12) | 50 (12) | 49 (14) | 48 (13) | 50 (13) |
Bodily pain (BP) Adj B (95 % CI) |
p
| General health (GH) Adj B (95 % CI) |
p
| Physical function (PF) Adj B (95 % CI) |
p
| Physical role (RP) lim. Adj B (95 % CI) |
p
| Mental health (MH) Adj B (95 % CI) |
p
| |
---|---|---|---|---|---|---|---|---|---|---|
Demographics | ||||||||||
Male | 5.2 (−2.5–12.9) | 0.19 | 0.5 (−5.3–6.3) | 0.86 | −0.4 (−4.4–3.7) | 0.85 | 4.6 (−7.0–16.2) | 0.43 | 2.3 (−3.0–7.7) | 0.39 |
High education | 5.0 (−3.5–13.5) | 0.24 | 0.7 (−5.7–7.2) | 0.82 | 0.7 (−3.7–5.2) | 0.75 | −7.4 (−20.2–5.3) | 0.25 | −4.8 (−10.6–1.1) | 0.11 |
Working at baseline | 7.9 (−1.0–16.8) | 0.08 | 3.9 (−2.6–10.5) | 0.24 |
5.1 (0.4–9.8)
|
0.03
|
24.3 (10.5–38.2)
|
0.001
| 0.7 (−5.2–6.6) | 0.82 |
Living together | 1.3 (−7.7–10.3) | 0.78 | −2.8 (−9.5–4.0) | 0.42 | 0.6 (−4.2–5.5) | 0.80 | −2.2 (−15.8–11.4) | 0.75 | 0.4 (−5.8–6.6) | 0.91 |
Age* | 0.1 (−0.3–0.5) | 0.57 | 0.1 (−0.2–0.4) | 0.61 | 0.0 (−0.2–0.2) | 0.76 | 0.2 (−0.4–0.8) | 0.45 | 0.1 (−0.2–0.3) | 0.65 |
IIG group | 0.1 (−7.8–8.0) | 0.57 | 0.7 (−5.1–6.6) | 0.81 | −0.2 (−4.3–3.9) | 0.93 | −4.7 (−16.4–7.1) | 0.43 | −2.6 (−8.0–2.7) | 0.33 |
Improved weight and fitness** |
15.4 (5.7–25.1)
|
0.002
|
12.7 (5.4–19.9)
|
0.001
|
8.9 (3.8–14.0)
|
0.001
| 12.1 (−2.4–26.6) | 0.10 | 5.6 (−1.1–12.2) | 0.10 |
Adjustment for baseline value*** | −0.4 (−0.5–0.2) | <0.001 | −0.3 (−0.5–0.2) | <0.001 | −0.5 (−0.6–0.3) | <0.001 | −0.6 (−0.8–0.4) | <0.001 | −0.5 (−0.7–0.3) | <0.001 |
R
2 adjusted | 22.3 % | 19.1 % | 39.1 % | 32.2 % | 20.6 % |
Social function (SF) Adj B (95 % CI) |
p
| Vitality (VT) Adj B (95 % CI) |
p
| Emot. role (RE) lim. Adj B (95 % CI) |
p
| Phys. comp. sum. (PCS) Adj B (95 % CI) |
p
| Ment. comp. sum (MCS) Adj B (95 % CI) |
p
| |
---|---|---|---|---|---|---|---|---|---|---|
Demographics | ||||||||||
Male | 1.7 (−5.0–8.5) | 0.61 | 3.0 (−4.0–10.0) | 0.40 | 3.0 (−7.0–12.9) | 0.56 | 1.1 (−1.6–3.8) | 0.44 | 0.7 (−3.3–4.7) | 0.74 |
High education | −5.5 (−12.9–1.9) | 0.15 | −2.5 (−10.1–5.1) | 0.52 | −3.2 (−14.0–7.6) | 0.56 | 0.8 (−2.2–3.7) | 0.62 | −2.9 (−7.2–1.5) | 0.19 |
Working at baseline |
8.1 (0.6–15.5)
|
0.04
| 5.6 (−2.1–13.4) | 0.15 | −4.6 (−15.5–6.3) | 0.41 |
4.3 (1.1–7.5)
|
0.009
| −1.1 (−5.4–3.2) | 0.61 |
Living together | 3.3 (−4.5–11.2) | 0.40 | −1.5 (−9.5–6.5) | 0.71 | −4.7 (−16.2–6.7) | 0.41 | −0.8 (−3.7–2.2) | 0.62 | −0.1 (−4.6–4.5) | 0.98 |
Age* | 0.3 (−0.1–0.6) | 0.13 | 0.0 (−0.3–0.4) | 0.88 | −0.1 (−0.6–0.4) | 0.70 | 0.0 (−0.1–0.2) | 0.48 | 0.0 (−0.2–0.2) | 0.94 |
IIG group | −2.4 (−9.2–4.4) | 0.49 | −5.8 (−12.7–1.1) | 0.10 | −4.6 (−14.6–5.4) | 0.36 | 0.2 (−2.6–3.0) | 0.89 | −2.7 (−6.7–1.3) | 0.18 |
Improved weight and fitness** |
11.3 (2.9–19.7)
|
0.01
|
11.3 (2.8–19.9)
|
0.01
| −1.3 (−13.6–11.1) | 0.84 |
6.4 (2.9–9.8)
|
<0.001
| 2.2 (−2.7–7.1) | 0.38 |
Adjustment for baseline value*** | −0.5 (−0.7–0.4) | <0.001 | −0.4 (−0.6–0.3) | <0.001 | −0.5 (−0.7–0.4) | <0.001 | −0.4 (−0.5–0.3) | <0.001 | −0.4 (−0.6–0.2) | <0.001 |
R
2 adjusted | 31.5 % | 22.2 % | 31.6 % | 28.7 % | 15.6 % |