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Gepubliceerd in: Quality of Life Research 1/2014

01-02-2014

Few items in the thyroid-related quality of life instrument ThyPRO exhibited differential item functioning

Auteurs: Torquil Watt, Mogens Groenvold, Laszlo Hegedüs, Steen Joop Bonnema, Åse Krogh Rasmussen, Ulla Feldt-Rasmussen, Jakob Bue Bjorner

Gepubliceerd in: Quality of Life Research | Uitgave 1/2014

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Abstract

Objective

To evaluate the extent of differential item functioning (DIF) within the thyroid-specific quality of life patient-reported outcome measure, ThyPRO, according to sex, age, education and thyroid diagnosis.

Study design and setting

A total of 838 patients with benign thyroid diseases completed the ThyPRO questionnaire (84 five-point items, 13 scales). Uniform and nonuniform DIF were investigated using ordinal logistic regression, testing for both statistical significance and magnitude (∆R 2 > 0.02). Scale level was estimated by the sum score, after purification.

Results

Twenty instances of DIF in 17 of the 84 items were found. Eight according to diagnosis, where the goiter scale was the one most affected, possibly due to differing perceptions in patients with auto-immune thyroid diseases compared to patients with simple goiter. Eight DIFs according to age were found, of which 5 were in positively worded items, which younger patients were more likely to endorse; one according to gender: women were more likely to report crying, and three according to educational level. The vast majority of DIF had only minor influence on the scale scores (0.1–2.3 points on the 0–100 scales), but two DIF corresponded to a difference of 4.6 and 9.8, respectively.

Conclusion

Ordinal logistic regression identified DIF in 17 of 84 items. The potential impact of this on the present scales was low, but items displaying DIF could be avoided when developing abbreviated scales, where the potential impact of DIF (due to fewer items) will be larger.
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Metagegevens
Titel
Few items in the thyroid-related quality of life instrument ThyPRO exhibited differential item functioning
Auteurs
Torquil Watt
Mogens Groenvold
Laszlo Hegedüs
Steen Joop Bonnema
Åse Krogh Rasmussen
Ulla Feldt-Rasmussen
Jakob Bue Bjorner
Publicatiedatum
01-02-2014
Uitgeverij
Springer International Publishing
Gepubliceerd in
Quality of Life Research / Uitgave 1/2014
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-013-0462-1

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