Skip to main content
Top
Gepubliceerd in: Quality of Life Research 3/2010

01-04-2010 | Brief Communication

Socio-demographic and clinical determinants of quality of life in Chinese patients with schizophrenia: a prospective study

Auteurs: Yu-Tao Xiang, Chuan-Yue Wang, Ying Wang, Helen F. K. Chiu, Jing-Ping Zhao, Qi Chen, Sandra S. M. Chan, Edwin H. M. Lee, Gabor S. Ungvari

Gepubliceerd in: Quality of Life Research | Uitgave 3/2010

Log in om toegang te krijgen
share
DELEN

Deel dit onderdeel of sectie (kopieer de link)

  • Optie A:
    Klik op de rechtermuisknop op de link en selecteer de optie “linkadres kopiëren”
  • Optie B:
    Deel de link per e-mail

Abstract

Purpose

The aim of the study was to assess the changes in the quality of life (QOL) of Chinese schizophrenia patients and to identify their predictors over a 1-year follow-up.

Methods

A cohort of 116 schizophrenia patients was recruited, and their socio-demographic and clinical characteristics including psychotic and depressive symptoms, drug-induced side effects, social functioning, and QOL were assessed with standardized rating instruments. The patients received standard psychiatric care and were followed up for 1 year.

Results

The psychotic and depressive symptoms, extrapyramidal side effects, and QOL domains of physical functioning, role limitations due to physical problems, social functioning, and role limitations due to emotional problems all improved significantly. Social functioning was a predictor of baseline QOL and change at 1-year follow-up.

Conclusions

Routine clinical management was effective in improving schizophrenia patients’ psychopathology and several domains of QOL. QOL was related to the level of social functioning and had only a weak association with socio-demographic factors.
Literatuur
1.
go back to reference Sartorius, N. (1997). Quality of life, mental disorders: A global perspective. Chichester: John Wiley. Sartorius, N. (1997). Quality of life, mental disorders: A global perspective. Chichester: John Wiley.
2.
go back to reference Chan, G. W., Ungvari, G. S., Shek, D. T., & Leung Dagger, J. J. (2003). Hospital and community-based care for patients with chronic schizophrenia in Hong Kong—Quality of life and its correlates. Social Psychiatry and Psychiatric Epidemiology, 38, 196–203.CrossRefPubMed Chan, G. W., Ungvari, G. S., Shek, D. T., & Leung Dagger, J. J. (2003). Hospital and community-based care for patients with chronic schizophrenia in Hong Kong—Quality of life and its correlates. Social Psychiatry and Psychiatric Epidemiology, 38, 196–203.CrossRefPubMed
3.
go back to reference Law, C. W., Chen, E. Y., Cheung, E. F., Chan, R. C., Wong, J. G., Lam, C. L., et al. (2005). Impact of untreated psychosis on quality of life in patients with first-episode schizophrenia. Quality of Life Research, 14, 1803–1811.CrossRefPubMed Law, C. W., Chen, E. Y., Cheung, E. F., Chan, R. C., Wong, J. G., Lam, C. L., et al. (2005). Impact of untreated psychosis on quality of life in patients with first-episode schizophrenia. Quality of Life Research, 14, 1803–1811.CrossRefPubMed
4.
go back to reference Xiang, Y. T., Weng, Y. Z., Leung, C. M., Tang, W. K., & Ungvari, G. S. (2008). Socio-demographic and clinical correlates of lifetime suicide attempts and their impact on quality of life in Chinese schizophrenia patients. Journal of Psychiatric Research, 42, 495–502.CrossRefPubMed Xiang, Y. T., Weng, Y. Z., Leung, C. M., Tang, W. K., & Ungvari, G. S. (2008). Socio-demographic and clinical correlates of lifetime suicide attempts and their impact on quality of life in Chinese schizophrenia patients. Journal of Psychiatric Research, 42, 495–502.CrossRefPubMed
5.
go back to reference Xiang, Y. T., Weng, Y. Z., Leung, C. M., Tang, W. K., & Ungvari, G. S. (2008). Subjective quality of life in outpatients with schizophrenia in Hong Kong and Beijing: Relationship to socio-demographic and clinical factors. Quality of Life Research, 17, 27–36.CrossRefPubMed Xiang, Y. T., Weng, Y. Z., Leung, C. M., Tang, W. K., & Ungvari, G. S. (2008). Subjective quality of life in outpatients with schizophrenia in Hong Kong and Beijing: Relationship to socio-demographic and clinical factors. Quality of Life Research, 17, 27–36.CrossRefPubMed
6.
go back to reference Xiang, Y. T., Weng, Y. Z., Leung, C. M., Tang, W. K., Lai, K. Y., & Ungvari, G. S. (2009). Prevalence and correlates of insomnia and its impact on quality of life in Chinese schizophrenia patients. Sleep, 32, 105–109.PubMed Xiang, Y. T., Weng, Y. Z., Leung, C. M., Tang, W. K., Lai, K. Y., & Ungvari, G. S. (2009). Prevalence and correlates of insomnia and its impact on quality of life in Chinese schizophrenia patients. Sleep, 32, 105–109.PubMed
7.
go back to reference He, Y. L., & Zhang, M. Y. (1997). The positive and negative syndrome scale (PANSS) and its application (in Chinese). Journal of Clinical Psychiatry, 7, 353–355. He, Y. L., & Zhang, M. Y. (1997). The positive and negative syndrome scale (PANSS) and its application (in Chinese). Journal of Clinical Psychiatry, 7, 353–355.
8.
go back to reference Montgomery, S. A., & Asberg, M. (1979). A new depression scale designed to be sensitive to change. British Journal of Psychiatry, 134, 382–389.CrossRefPubMed Montgomery, S. A., & Asberg, M. (1979). A new depression scale designed to be sensitive to change. British Journal of Psychiatry, 134, 382–389.CrossRefPubMed
9.
go back to reference Simpson, G. M., & Angus, J. W. (1970). A rating scale for extrapyramidal side effects. Acta Psychiatrica Scandinavica, 212(Supplementum), 11–19.CrossRef Simpson, G. M., & Angus, J. W. (1970). A rating scale for extrapyramidal side effects. Acta Psychiatrica Scandinavica, 212(Supplementum), 11–19.CrossRef
10.
go back to reference Wu, W. Y. (1998). Social Disability Screening Schedule-Chinese version. In M. Y. Zhang (Ed.), Handbook of rating scales in psychiatry (pp 163–166). Changsha: Hunan, Hunan Science and Technology Press. Wu, W. Y. (1998). Social Disability Screening Schedule-Chinese version. In M. Y. Zhang (Ed.), Handbook of rating scales in psychiatry (pp 163–166). Changsha: Hunan, Hunan Science and Technology Press.
11.
go back to reference Xu, J., Hu, M. Y., Yang, Y. B., Wang, B. H., & Xie, Y. N. (1999). Medical outcome study 36 item short form (SF-36) (in Chinese). Chinese Journal of Behavioral Medical Science, 8, 150–152. Xu, J., Hu, M. Y., Yang, Y. B., Wang, B. H., & Xie, Y. N. (1999). Medical outcome study 36 item short form (SF-36) (in Chinese). Chinese Journal of Behavioral Medical Science, 8, 150–152.
12.
go back to reference Xu, D., & Xu, D. M. (2001). Investigation of marital status for 758 schizophrenics (in Chinese). Zhongyuan Mental Health, 7, 136–139. Xu, D., & Xu, D. M. (2001). Investigation of marital status for 758 schizophrenics (in Chinese). Zhongyuan Mental Health, 7, 136–139.
13.
go back to reference Guo, Z. Y., Liu, J. M., Zhang, J. Z., Guo, H., & Wang, A. Q. (2008). Efficacy of quetiapine in the treatment of schizophrenic patients and its effect on quality of life (in Chinese). Chinese Journal of Health Psychology, 16, 544–546. Guo, Z. Y., Liu, J. M., Zhang, J. Z., Guo, H., & Wang, A. Q. (2008). Efficacy of quetiapine in the treatment of schizophrenic patients and its effect on quality of life (in Chinese). Chinese Journal of Health Psychology, 16, 544–546.
14.
go back to reference Potkin, S. G., Weiden, P. J., Loebel, A. D., Warrington, L. E., Watsky, E. J., & Siu, C. O. (2009). Remission in schizophrenia: 196-week, double-blind treatment with ziprasidone vs. haloperidol. International Journal of Neuropsychopharmacology, 12, 1233–1248. Potkin, S. G., Weiden, P. J., Loebel, A. D., Warrington, L. E., Watsky, E. J., & Siu, C. O. (2009). Remission in schizophrenia: 196-week, double-blind treatment with ziprasidone vs. haloperidol. International Journal of Neuropsychopharmacology, 12, 1233–1248.
15.
go back to reference Wegener, S., Redoblado-Hodge, M. A., Lucas, S., Fitzgerald, D., Harris, A., & Brennan, J. (2005). Relative contributions of psychiatric symptoms and neuropsychological functioning to quality of life in first-episode psychosis. Australian and New Zealand Journal of Psychiatry, 39, 487–492.PubMed Wegener, S., Redoblado-Hodge, M. A., Lucas, S., Fitzgerald, D., Harris, A., & Brennan, J. (2005). Relative contributions of psychiatric symptoms and neuropsychological functioning to quality of life in first-episode psychosis. Australian and New Zealand Journal of Psychiatry, 39, 487–492.PubMed
16.
go back to reference Browne, S., Roe, M., Lane, A., Gervin, M., Morris, M., Kinsella, A., et al. (1996). Quality of life in schizophrenia: Relationship to sociodemographic factors, symptomatology and tardive dyskinesia. Acta Psychiatrica Scandinavica, 94, 118–124.CrossRefPubMed Browne, S., Roe, M., Lane, A., Gervin, M., Morris, M., Kinsella, A., et al. (1996). Quality of life in schizophrenia: Relationship to sociodemographic factors, symptomatology and tardive dyskinesia. Acta Psychiatrica Scandinavica, 94, 118–124.CrossRefPubMed
17.
go back to reference Corrigan, P. W., & Buican, B. (1995). The construct validity of subjective quality of life for the severely mentally ill. Journal of Nervous and Mental Disease, 183, 281–285.PubMedCrossRef Corrigan, P. W., & Buican, B. (1995). The construct validity of subjective quality of life for the severely mentally ill. Journal of Nervous and Mental Disease, 183, 281–285.PubMedCrossRef
18.
go back to reference Xiang, Y. T., Weng, Y. Z., Leung, C. M., Tang, W. K., & Ungvari, G. S. (2007). Quality of life of Chinese schizophrenia outpatients in Hong Kong: Relationship to sociodemographic factors and symptomatology. Australian and New Zealand Journal of Psychiatry, 41, 442–449.CrossRefPubMed Xiang, Y. T., Weng, Y. Z., Leung, C. M., Tang, W. K., & Ungvari, G. S. (2007). Quality of life of Chinese schizophrenia outpatients in Hong Kong: Relationship to sociodemographic factors and symptomatology. Australian and New Zealand Journal of Psychiatry, 41, 442–449.CrossRefPubMed
19.
go back to reference Kwon, J. S., & Choi, J. S. (2009). Social functioning and quality of life as measures of effectiveness in the treatment of schizophrenia. World Psychiatry, 8, 35–36.PubMed Kwon, J. S., & Choi, J. S. (2009). Social functioning and quality of life as measures of effectiveness in the treatment of schizophrenia. World Psychiatry, 8, 35–36.PubMed
20.
go back to reference Trompenaars, F. J., Masthoff, E. D., Van Heck, G. L., De Vries, J., & Hodiamont, P. P. (2007). Relationships between social functioning and quality of life in a population of Dutch adult psychiatric outpatients. International Journal of Social Psychiatry, 53, 36–47.CrossRefPubMed Trompenaars, F. J., Masthoff, E. D., Van Heck, G. L., De Vries, J., & Hodiamont, P. P. (2007). Relationships between social functioning and quality of life in a population of Dutch adult psychiatric outpatients. International Journal of Social Psychiatry, 53, 36–47.CrossRefPubMed
21.
go back to reference Franz, M., Meyer, T., Reber, T., & Gallhofer, B. (2000). The importance of social comparisons for high levels of subjective quality of life in chronic schizophrenic patients. Quality of Life Research, 9, 481–489.CrossRefPubMed Franz, M., Meyer, T., Reber, T., & Gallhofer, B. (2000). The importance of social comparisons for high levels of subjective quality of life in chronic schizophrenic patients. Quality of Life Research, 9, 481–489.CrossRefPubMed
22.
go back to reference Katschnig, H. (2000). Schizophrenia and quality of life. Acta Psychiatrica Scandinavica, 407(Suppl), 33–37. Katschnig, H. (2000). Schizophrenia and quality of life. Acta Psychiatrica Scandinavica, 407(Suppl), 33–37.
Metagegevens
Titel
Socio-demographic and clinical determinants of quality of life in Chinese patients with schizophrenia: a prospective study
Auteurs
Yu-Tao Xiang
Chuan-Yue Wang
Ying Wang
Helen F. K. Chiu
Jing-Ping Zhao
Qi Chen
Sandra S. M. Chan
Edwin H. M. Lee
Gabor S. Ungvari
Publicatiedatum
01-04-2010
Uitgeverij
Springer Netherlands
Gepubliceerd in
Quality of Life Research / Uitgave 3/2010
Print ISSN: 0962-9343
Elektronisch ISSN: 1573-2649
DOI
https://doi.org/10.1007/s11136-010-9593-9

Andere artikelen Uitgave 3/2010

Quality of Life Research 3/2010 Naar de uitgave