Abstract
The aim of this study was to resolve the relationship between physical capacity (PC) and quality of life (Qol) in schizophrenic patients and healthy controls. 31 patients (PG: 18 male, 13 female) and a control group (CG) of 50 healthy subjects (15 male, 35 female) were involved. PC was assessed as peak oxygen uptake [VO2peak, (ml (min kgKG)−1)] and power output expressed as watts per kilogram (W kg−1). Qol was assessed using the SF-36 questionnaire. Patients with schizophrenia showed reduced VO2peak (male: PG 29 ± 5 vs. CG 44 ± 10; female: PG 21 ± 4 vs. CG 30 ± 8) and power output (male: PG 2.04 ± 0.47 vs. CG 3.43 ± 0.70; female PG 1.40 ± 0.28 vs. CG 2.43 ± 0.52). Scales of the SF-36 questionnaire were lower in the PG. While in the CG correlations were found between PC and several subscales of Qol, this was not the case in the PG. The restricted PC seen in the PG showed no relation to their subjectively assessed worsened Qol, which would indicate that schizophrenic patients evaluate limitations arising from this differently than healthy control subjects.
Similar content being viewed by others
References
Harris EC, Barraclough B: Excess mortality of mental disorder. The British Journal of Psychiatry 173:11–53, 1998.
Leucht S, Burkard T, Henderson J, Maj M, Sartorius N: Physical illness and schizophrenia: A review of the literature. Acta Psychiatrica Scandinavica 116(5):317–333, 2007.
Saha S, Chant D, McGrath J: A systematic review of mortality in schizophrenia: Is the differential mortality gap worsening over time? Archives of General Psychiatry 64(10):1123–1131, 2007.
Brown S, Kim M, Mitchell C, Inskip H: Twenty-five year mortality of a community cohort with schizophrenia. The British Journal of Psychiatry 196(2):116–121, 2010.
Tran E, Rouillon F, Loze JY, Casadebaig F, Philippe A, Vitry F, et al.: Cancer mortality in patients with schizophrenia: An 11-year prospective cohort study. Cancer 115(15):3555–3562, 2009.
Wildgust HJ, Beary M: Are there modifiable risk factors which will reduce the excess mortality in schizophrenia? Journal of Psychopharmacology 24(4 Suppl):37–50, 2010.
Kodama S, Saito K, Tanaka S, Maki M, Yachi Y, Asumi M, et al.: Cardiorespiratory fitness as a quantitative predictor of all-cause mortality and cardiovascular events in healthy men and women: A meta-analysis. JAMA 301(19):2024–2035, 2009.
Blair SN: Physical inactivity: The biggest public health problem of the 21st century. British Journal of Sports Medicine 43(1):1–2, 2009.
Brown S, Birtwistle J, Roe L, Thompson C: The unhealthy lifestyle of people with schizophrenia. Psychological Medicine 29(3):697–701, 1999.
Laursen TM, Munk-Olsen T, Agerbo E, Gasse C, Mortensen PB: Somatic hospital contacts, invasive cardiac procedures, and mortality from heart disease in patients with severe mental disorder. Archives of General Psychiatry 66(7):713–720, 2009.
Newcomer JW: Metabolic risk during antipsychotic treatment. Clinical Therapeutics 26(12):1936–1946, 2004.
Allison DB, Casey DE: Antipsychotic-induced weight gain: A review of the literature. The Journal of Clinical Psychiatry 62(Suppl 7):22–31, 2001.
Alvarez-Jimenez M, Hetrick SE, Gonzalez-Blanch C, Gleeson JF, McGorry PD: Non-pharmacological management of antipsychotic-induced weight gain: Systematic review and meta-analysis of randomised controlled trials. The British Journal of Psychiatry 193(2):101–107, 2008.
Borg G: Borg’s Perceived Exertion and Pain Scales. Champaign, Human Kinetics, 1998.
Löllgen H: Das Anstrengungsempfinden (RPE, Borg-Skala). Deutsche Zeitschrift für Sportmedizin 55(11): 299–300, 2004.
Overall JE, Gorham DR: The brief psychiatric rating scale. Psychological Reports 10(3):799–812, 1962.
Bullinger M: Assessment of health related quality of life with the SF-36 Health Survey. Rehabilitation (Stuttg) 35(3):XVII–XXVII; quiz XXVII–XXIX, 1996.
Ware JE Jr., Sherbourne CD: The MOS 36-item short-form health survey (SF-36). I. Conceptual framework and item selection. Medical Care 30(6):473–483, 1992.
Leese M, Schene A, Koeter M, Meijer K, Bindman J, Mazzi M, et al.: SF-36 scales, and simple sums of scales, were reliable quality-of-life summaries for patients with schizophrenia. Journal of Clinical Epidemiology 61(6):588–596, 2008.
Pukrop R, Schlaak V, Moller-Leimkuhler AM, Albus M, Czernik A, Klosterkotter J, et al.: Reliability and validity of Quality of Life assessed by the Short-Form 36 and the Modular System for Quality of Life in patients with schizophrenia and patients with depression. Psychiatry Research 119(1–2):63–79, 2003.
Nilsson BM, Olsson RM, Oman A, Wiesel FA, Ekselius L, Forslund AH: Physical capacity, respiratory quotient and energy expenditure during exercise in male patients with schizophrenia compared with healthy controls. European Psychiatry 27(3):206–212, 2012.
Deimel H, Lohmann S: Physical capacity of schizophrenic patients. Rehabilitation (Stuttg) 22(2):81–85, 1983.
Dodd KJ, Duffy S, Stewart JA, Impey J, Taylor N: A small group aerobic exercise programme that reduces body weight is feasible in adults with severe chronic schizophrenia: a pilot study. Disability and Rehabilitation 33(13–14):1222–1229, 2011.
Strassnig M, Brar JS, Ganguli R: Low cardiorespiratory fitness and physical functional capacity in obese patients with schizophrenia. Schizophrenia Research 126(1–3):103–109, 2011.
Vancampfort D, Probst M, Sweers K, Maurissen K, Knapen J, De Hert M: Relationships between obesity, functional exercise capacity, physical activity participation and physical self-perception in people with schizophrenia. Acta Psychiatrica Scandinavica 123(6):423–430, 2011.
Hofer A, Kemmler G, Eder U, Edlinger M, Hummer M, Fleischhacker WW: Quality of life in schizophrenia: The impact of psychopathology, attitude toward medication, and side effects. The Journal of Clinical Psychiatry 65(7):932–939, 2004.
Schennach-Wolff R, Jager M, Obermeier M, Schmauss M, Laux G, Pfeiffer H, et al.: Quality of life and subjective well-being in schizophrenia and schizophrenia spectrum disorders: Valid predictors of symptomatic response and remission? The World Journal of Biological Psychiatry 11(5):729–738, 2010.
Allison DB, Mackell JA, McDonnell DD: The impact of weight gain on quality of life among persons with schizophrenia. Psychiatric Services 54(4):565–567, 2003.
Kolotkin RL, Corey-Lisle PK, Crosby RD, Swanson JM, Tuomari AV, L’italien GJ, et al.: Impact of obesity on health-related quality of life in schizophrenia and bipolar disorder. Obesity (Silver Spring) 16(4):749–754, 2008.
Faulkner G, Cohn T, Remington G, Irving H: Body mass index, waist circumference and quality of life in individuals with schizophrenia. Schizophrenia Research 90(1–3):174–178, 2007.
Bronner M, Betz C, Christ S, Frobose T, Pitschel-Walz G, Bauml J: Wellness-activities to prevent metabolic syndrome among patients with schizophrenia. Psychiatrische Praxis 37(1):7–19, 2010.
Acknowledgments
We thank Mr Kück, who provided the data necessary for our analysis.
Conflict of interest
The authors declare that they have no conflict of interest.
Author information
Authors and Affiliations
Corresponding author
Rights and permissions
About this article
Cite this article
Kerling, A., Tegtbur, U., Ziegenbein, M. et al. Exercise Capacity and Quality of Life in Patients with Schizophrenia. Psychiatr Q 84, 417–427 (2013). https://doi.org/10.1007/s11126-013-9256-4
Published:
Issue Date:
DOI: https://doi.org/10.1007/s11126-013-9256-4