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Is ACEs Screening for Adolescent Mental Health Accurate and Fair?

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Abstract

Increasingly, adversity-focused assessment tools are being introduced into preventive mental health screening protocols. However, few studies have explicitly examined whether use of these instruments serves as equitable, clinically useful measures of mental health risk in adolescents. In response, the present study examined whether an adverse childhood experiences (ACEs) measure was accurate and fair as an index of environmental risk for adolescent mental health diagnoses. Secondary data analyses were conducted on the National Comorbidity Survey-Adolescent Supplement. Adolescents (N = 10,148; AgeMean = 15.20; 51.3% male; 65.6% White, 15.1% Black, and 14.4% Hispanic) answered ten questions concerning childhood adversities and completed diagnostic interviews for PTSD, depression, and externalizing disorders. In the overall sample, ACEs showed some clinical utility (e.g., area under the curve (AUCs) ≥ 0.64), diagnostic likelihood ratios (DLRs) > 4.0) and acceptable calibration (i.e., expected/observed indices’ confidence intervals included 1) across diagnoses. Within subpopulations, however, predictive validity varied. The AUCs were lower for multiple diagnoses in Black male and Hispanic female adolescents and DLRs suggested greater clinical utility for indexing mental health in White, female adolescents. Finally, models were not well-calibrated between adolescent subpopulations, suggesting recommended ACEs screening can potentially produce biased results when used to inform mental health policy and prevention. Reasons for why results from ACEs screening may vary across adolescent subpopulations and the importance of testing statistical fairness for preventive mental health screening are discussed.

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Notes

  1. A total of 8 groups were compared for these analyses. Adolescents who did not identify as White, Black, or Hispanic were grouped into an “other” category. These four racial/ethnic groups were then grouped as male or female. Gender was coded as a binary category in the NCS-A study.

  2. Of note, the E/O index for threshold scores did not include 1 (see Table 3). This suggests we were not able to replicate the rate at which White female adolescents report depression within the context of above threshold ACEs score. Similarly, the E/O index for threshold scores did not include 1 for depression in Hispanic males.

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Funding

The National Comorbidity Survey-Adolescent Supplement was supported by the National Institute of Mental Health (NIMH; U01-MH60220) with supplemental support from NIDA, SAMHSA, the Robert Wood Johnson Foundation, and the John W. Alden Trust. JRC’s time on this manuscript was funded by the National Institute of Justice (2018-R2-CX-0022).

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Correspondence to Joseph R. Cohen.

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Ethical Approval

The recruitment and consent procedures were approved by the human subjects committees of both Harvard Medical School and the University of Michigan. The secondary data analysis on this study was approved by the first author’s Institutional Review Board.

Informed Consent

Written informed parental consent and written informed adolescent assent was obtained from all participants prior to participation in the study.

Conflict of Interest

The authors declare no competing interests.

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Cohen, J.R., Choi, J.W. Is ACEs Screening for Adolescent Mental Health Accurate and Fair?. Prev Sci 23, 1216–1229 (2022). https://doi.org/10.1007/s11121-022-01391-3

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