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Six- and Twelve-Month Follow-up Results of a Cluster Randomized Controlled Trial of a CBT-Based Group Course

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Abstract

In the current study, we examined the durability of intervention gains over a 6- and 12-month follow-up period after the implementation of a CBT-based group intervention “Adolescent Coping with Depression Course” (ACDC) for adolescents with subclinical or mild-to-moderate depression. Data were collected from 228 youth, 133 of whom were allocated to the 14-week ACDC intervention and 95 to the usual care (UC) control condition. Analyses for the main outcome variable of depressive symptoms were performed using a random effects repeated measures piecewise growth model to estimate trajectory shape over time on an intention-to-treat basis. Results revealed that the reduction in depressive symptoms achieved during the intervention phase continued across the follow-up period for both ACDC and UC (i.e., depressive symptoms showed a significantly decreasing trend in both groups in intervention and follow-up phases); however, no differential effects between conditions were found during the follow-up phase. The direct and indirect effects of the intervention on the other outcome variables’ follow-up results were also presented. ISRCTN registry ISRCTN19700389. Registered 6 October 2015. https://doi.org/10.1186/ISRCTN19700389. Full Protocol: https://doi.org/10.1186/s12888-016-0954-y

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Notes

  1. The immediate intervention effect on each of these variables was reported in the original trial.

  2. Since bootstrapping estimation cannot be employed either with MLR or with auxiliary variables in Mplus, we used ML estimation without auxiliary variables in bootstrapping.

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Funding

This study was funded by The Research Council of Norway through the program “Research and Innovation in the Educational Sector” (FINNUT) (project number 238081/H20). Additional funding from Gidske og Peter Jacob Sørensens fond, and the Norwegian Directorate of Health.

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Correspondence to Serap Keles.

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The authors declare that they have no conflict of interest.

Informed Consent

All participants in this study provided informed consent prior to enrollment. They were also informed that participating in the study was voluntary and that participants could at any time and without any given reason withdraw their consent to participate. This would not affect their further participation on the course or in the usual care treatment. Contact information was provided for these issues.

Research Involving Human Participants and/or Animals

All procedures in this study were has been performed in accordance with the Declaration of Helsinki, and has been approved by The Norwegian Regional Committee for Medical and Health Research Ethics (South East). Approval reference: 2015/1027 Depresjonsmestring for ungdom.

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Keles, S., Idsoe, T. Six- and Twelve-Month Follow-up Results of a Cluster Randomized Controlled Trial of a CBT-Based Group Course. Prev Sci 22, 409–418 (2021). https://doi.org/10.1007/s11121-020-01160-0

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