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Impact of community pharmaceutical care on patient health and quality of drug treatment in Parkinson’s disease

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Abstract

Background The well-being of patients with Parkinson’s disease may be improved by pharmaceutical care in community pharmacies. Objective To investigate the effects of standardised pharmaceutical care on health outcomes and quality of drug treatment in patients with Parkinson’s disease. Setting Community pharmacies in Germany. Method An open-label, multicentre, longitudinal, parallel-group study was conducted in outpatients with idiopathic Parkinson’s disease who were receiving anti-parkinsonian medication. Patients were recruited by 32 community pharmacists (pharmacy group) and local offices of the German Parkinson’s disease patients’ association (comparison group). All patients were assessed at baseline and at 8 months’ follow-up. In the intervening period, the pharmacists provided patients in the pharmacy group with standardised pharmaceutical care. Main outcome measure Mean change in symptom-related impairment of health status, assessed using the 23-item Parkinson’s Scale Total Score. Results In total 235 patients were enrolled into the study (113 pharmacy group; 122 comparison group). Between-group analysis showed that the mean changes in the primary and secondary endpoints, all 23-item Parkinson’s Scale sub-scores and the EuroQol 5-Dimension Questionnaire Index Score were significantly in favour of the pharmacy group after 8 months (p < 0.05 to p < 0.001), using a mixed model analysis. No significant changes were observed in prescribers’ guideline adherence, but there was a significant decrease in the proportion of patients receiving inappropriate drugs according to the Beers List in the pharmacy group (p < 0.01). Conclusion This study shows that significant benefits in patient health outcomes and age-related quality of drug treatment were gained when patients with Parkinson’s disease were provided with standardised pharmaceutical care in community pharmacies.

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Acknowledgments

The authors would like to thank: the study pharmacists for participation in the study; the German PD patients’ association (Deutsche Parkinson Vereinigung e.V., Bundesverband); the patients, treating neurologists and physicians for their collaboration in the study; and Vicky Hinstridge and Chris Watling for their assistance in editing the final manuscript.

Funding

The study was supported by an unrestricted grant from Solvay Pharmaceuticals GmbH, Hanover, Germany.

Conflicts of interest

None of the authors has any relevant conflict.

Author information

Authors and Affiliations

  1. Institute of Clinical Pharmacology, Charité University Medicine, CCM, Invalidenstrasse 115, 10115, Berlin, Germany

    Sabrina Schröder & Marion Schaefer

  2. Institute for Clinical Epidemiology and Applied Biostatistics, Eberhard-Karls-University Tübingen, Westbahnhofstraße 55, 72070, Tübingen, Germany

    Peter Martus

  3. Department of Neurology, Central Hospital Bremerhaven, Postbrookstrasse 103, 27574, Bremerhaven, Germany

    Per Odin

  4. Department of Neurology, Lund University Hospital, 221 85, Lund, Sweden

    Per Odin

Authors
  1. Sabrina Schröder
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  2. Peter Martus
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  4. Marion Schaefer
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Correspondence to Sabrina Schröder.

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Schröder, S., Martus, P., Odin, P. et al. Impact of community pharmaceutical care on patient health and quality of drug treatment in Parkinson’s disease. Int J Clin Pharm 34, 746–756 (2012). https://doi.org/10.1007/s11096-012-9672-9

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  • DOI: https://doi.org/10.1007/s11096-012-9672-9

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