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Differences in adherence and motivation to HIV therapy—two independent assessments in 1998 and 2002

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Abstract

Objective

The aim of this study was to compare the level of adherence and motivation in two independent cross-sectional samples of HIV-infected patients conducted in 1998 and 2002, and to investigate the relationship between adherence and motivation.

Method

Consecutive HIV-infected patients on treatment at a Swedish clinic were asked to complete an anonymous questionnaire. In 1998, 60 patients participated and in 2002, 53 participated. In 2002, the 9-item Morisky Medication Adherence Scale (MMAS) was added to the questionnaire set.

Main outcome measure

Self-reported adherence and motivation.

Results

In 1998, 28.1% of the respondents were considered adherent, while the corresponding proportion was 57.4% in 2002 (P = 0.002). The mean summary score for MMAS was 10.7 in 2002 (13 = perfect adherence). The proportion considered motivated were 22.4% in the 1998 survey and 41.3% in 2002 (P = 0.038). Of the respondents considered motivated in the 2002 survey, 46.7% scored the maximum summary score on the MMAS, while 8.7% of the non-motivated respondents did so (P = 0.016).

Conclusion

The respondents in 2002 were more adherent and motivated than the respondents in 1998 and a relationship between motivation and adherence was found. The difference in adherence and motivation might be due to a new treatment model at the clinic.

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Acknowledgements

We thank the following people for their assistance: Colleagues at the HIV clinic, Karolinska University Hospital – Huddinge and also the colleagues at the Department of Pharmacy, Uppsala University. Supported by the Lennhof foundation, Swedish Pharmaceutical Academy, the Department of Infectious Diseases at Karolinska University Hospital – Huddinge and Hospital Pharmacy, Huddinge University Hospital. Potential conflicts of interest: none declared.

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Correspondence to Björn Södergård.

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Södergård, B., Halvarsson, M., Lindbäck, S. et al. Differences in adherence and motivation to HIV therapy—two independent assessments in 1998 and 2002. Pharm World Sci 28, 248–256 (2006). https://doi.org/10.1007/s11096-006-9036-4

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  • DOI: https://doi.org/10.1007/s11096-006-9036-4

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