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Episodic Memory in Schizophrenia

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Abstract

Episodic memory impairments in individuals with schizophrenia have been well documented in the literature. However, despite the abundance of findings, constituent cognitive, neural, behavioral, and genetic components of the deficits continue to elude full characterization. This review provides a characterization of these deficits by organizing findings within three frameworks of interest: 1) neuroanatomical; 2) genetic; and 3) behavioral. Within each approach, evidence from imaging studies as well as behavioral studies is examined. The hope is that by synthesizing the cognitive science paradigms, molecular genetic neurophysiological findings, and computational algorithms applied to medial temporal lobe subregions, we will be able to expand our understanding of the types of compromises in episodic memory systems of individuals with schizophrenia.

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Acknowledgments

Funding sources: 5 P30 MH074543-03 (Kane). Early Phase Schizophrenia: Optimizing Outcomes.

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The authors have no conflicts of interest relevant to this work.

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  1. The Zucker Hillside Hospital, 75-59 263rd Street, Glen Oaks, NY, 11004, USA

    Victoria M. Leavitt & Terry E. Goldberg

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  1. Victoria M. Leavitt
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Correspondence to Terry E. Goldberg.

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Leavitt, V.M., Goldberg, T.E. Episodic Memory in Schizophrenia. Neuropsychol Rev 19, 312–323 (2009). https://doi.org/10.1007/s11065-009-9107-0

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