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01-10-2015 | Empirical Research

Differential Susceptibility: The Genetic Moderation of Peer Pressure on Alcohol Use

Auteurs: Amanda M. Griffin, H. Harrington Cleveland, Gabriel L. Schlomer, David J. Vandenbergh, Mark E. Feinberg

Gepubliceerd in: Journal of Youth and Adolescence | Uitgave 10/2015

Abstract

Although peer pressure can influence adolescents’ alcohol use, individual susceptibility to these pressures varies across individuals. The dopamine receptor D4 gene (DRD4) is a potential candidate gene that may influence adolescents’ susceptibility to their peer environment due to the role dopamine plays in reward sensation during social interaction. We hypothesized that DRD4 genotype status would moderate the impact of 7th-grade antisocial peer pressure on 12th-grade lifetime alcohol use (n = 414; 58.7 % female; 92.8 % White). The results revealed significant main effects for antisocial peer pressure, but no main effects for DRD4 genotype on lifetime alcohol use. Adolescent DRD4 genotype moderated the association between peer pressure and lifetime alcohol use. For individuals who carried at least one copy of the DRD4 7-repeat allele (7+), antisocial peer pressure was associated with increased lifetime alcohol use. These findings indicate that genetic sensitivity to peer pressure confers increased alcohol use in late adolescence.

volgende artikel Moral Disengagement, Anticipated Social Outcomes and Adolescents’ Alcohol Use: Parallel Latent Growth Curve Analyses

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Titel: Differential Susceptibility: The Genetic Moderation of Peer Pressure on Alcohol Use
Auteurs: Amanda M. Griffin
H. Harrington Cleveland
Gabriel L. Schlomer
David J. Vandenbergh
Mark E. Feinberg
Publicatiedatum: 01-10-2015
Uitgeverij: Springer US
Gepubliceerd in: Journal of Youth and Adolescence / Uitgave 10/2015
Print ISSN: 0047-2891
Elektronisch ISSN: 1573-6601
DOI: https://doi.org/10.1007/s10964-015-0344-7

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