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Religiosity and Telomere Length in Colorectal Cancer Patients in Saudi Arabia

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Abstract

Numerous studies have reported a significant relationship between psychological stress, depression, and telomere length (TL), an indicator of cellular lifespan. Religious involvement, which is associated with lower levels of stress and depression, has also recently been related to TL. To our knowledge, this relationship has not yet been examined in Muslims, colorectal cancer patients, cancer patients more generally, or any population outside the USA. A convenience sample of 50 colorectal patients was recruited from hospital-based oncology clinics in Jeddah, Saudi Arabia. Religious involvement was assessed with the 13-item Muslim Religiosity Scale. Social and psychological mediators were measured using established scales. TL was determined from whole-blood leukocytes using quantitative PCR technology. Bivariate analyses indicated a positive but nonsignificant relationship between religiosity and TL (r = 0.13, p = 0.35). Controlling for age, did not affect the relationship (B = 15.6, SE = 17.3, p = 0.37), nor did controlling for other demographic, social or psychological factors. Religious involvement was unrelated to TL in this small sample of colorectal patients. Future cross-sectional and prospective studies in different populations with larger samples are needed.

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Acknowledgements

This study was supported and funded by the Colorectal Cancer Chair, King Abdulaziz University, Jeddah, Saudi Arabia.

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Authors and Affiliations

  1. Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia

    Mahmoud Shaheen Al Ahwal

  2. Department of Psychiatry, King Abdulaziz University, Jeddah, Saudi Arabia

    Faten Al Zaben, Mohammad Gamal Sehlo, Doaa Ahmed Khalifa & Harold G. Koenig

  3. Zagazig University, Zagazig, Egypt

    Mohammad Gamal Sehlo

  4. Ain Shams University, Cairo, Egypt

    Doaa Ahmed Khalifa

  5. Duke University Medical Center, Box 3400, Durham, NC, 27710, USA

    Harold G. Koenig

  6. School of Public Health, Ningxia Medical University, Yinchuan, People’s Republic of China

    Harold G. Koenig

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  1. Mahmoud Shaheen Al Ahwal
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  2. Faten Al Zaben
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  3. Mohammad Gamal Sehlo
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  4. Doaa Ahmed Khalifa
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  5. Harold G. Koenig
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Correspondence to Harold G. Koenig.

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Al Ahwal, M.S., Al Zaben, F., Sehlo, M.G. et al. Religiosity and Telomere Length in Colorectal Cancer Patients in Saudi Arabia. J Relig Health 57, 672–682 (2018). https://doi.org/10.1007/s10943-017-0542-6

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  • DOI: https://doi.org/10.1007/s10943-017-0542-6

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