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Stability of Autism Symptoms in Young Children

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Abstract

The study of early diagnosis and intervention has been a central theme in recent autism research. In support of the validity of early autism diagnoses, researchers have found discriminating variables that are identifiable within the first three years of life. In addition, autism diagnoses made within this time period are typically stable over time. Separate symptoms, however, seem to exhibit differential patterns across development. The current study examined the stability of autism screening outcomes and symptomology in 637 toddlers between the age of 17 and 36 months. Confirmatory of previous findings, results of the current study suggest that overall screening outcomes and symptom severity across three domains (i.e., socialization/nonverbal communication, restricted repetitive behaviors and interests, and communication) are stable across time. Further, the effects of age and time between testing were found to vary between groups. Implications of these results are discussed.

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References

  • American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders (5th ed.). Washington: American Psychiatric Association.

    Book  Google Scholar 

  • Baio, J. (2012). Prevalence of autism spectrum disorders: Autism and developmental disabilities monitoring network, 14 sites, United States, 2008. Morbidity and mortality weekly report. Surveillance summaries. Centers for Disease Control and Prevention. 61(3).

  • Bhat, S., Acharya, U. R., Adeli, H., Bairy, G. M., & Adeli, A. (2014). Autism: Cause factors, early diagnosis and therapies. Reviews in the Neurosciences, 25(6), 841–850. https://doi.org/10.1515/revneuro-2014-0056.

    PubMed  Google Scholar 

  • Chawarska, K., Klin, A., Paul, R., & Volkmar, F. (2007). Autism spectrum disorder in the second year: Stability and change in syndrome expression. Journal of Child Psychology and Psychiatry, 48(2), 128–138. https://doi.org/10.1111/j.1469-7610.2006.01685.x.

    Article  PubMed  Google Scholar 

  • Chawarska, K., Shic, F., Macari, S., Campbell, D. J., Brian, J., Landa, R., et al. (2014). 18-month predictors of later outcomes in younger siblings of children with autism spectrum disorder: A baby siblings research consortium study. Journal of the American Academy of Child & Adolescent Psychiatry, 53(12), 1317–1327.e1. https://doi.org/10.1016/j.jaac.2014.09.015.

    Article  Google Scholar 

  • Christensen, D. L., Baio, J., Van Naarden Braun, K., Bilder, D. A., Charles, J., Constantino, J. N., et al. (2016). Prevalence and characteristics of autism Spectrum disorder among children aged 8 years - autism and developmental disabilities monitoring network, 11 sites, United States, 2012. MMWR Surveillance Summaries, 65(3).

  • Cox, A., Klein, K., Charman, T., Baird, G., Baron-Cohen, S., Swettenham, J., & et al. (1999). Autism spectrum disorders at 20 and 42 months of age: Stability of clinical and ADI-R diagnosis. Journal of Child Psychology and Psychiatry, 40, 719–732.

  • Eldevik, S., Hastings, R. P., Hughes, J. C., Jahr, E., Eikeseth, S., & Cross, S. (2009). Meta-analysis of early intensive behavioral intervention for children with autism. Journal of Clinical Child & Adolescent Psychology, 38(3), 439–450. https://doi.org/10.1080/15374410902851739.

    Article  Google Scholar 

  • Elsabbagh, M., Fernandes, J., Jane Webb, S., Dawson, G., Charman, T., & Johnson, M. H. (2013). Disengagement of visual attention in infancy is associated with emerging autism in toddlerhood. Biological Psychiatry, 74(3), 189–194. https://doi.org/10.1016/j.biopsych.2012.11.030.

    Article  PubMed  PubMed Central  Google Scholar 

  • Guthrie, W., Swineford, L. B., Nottke, C., & Wetherby, A. M. (2013). Early diagnosis of autism spectrum disorder: Stability and change in clinical diagnosis and symptom presentation. Journal of Child Psychology and Psychiatry, 54(5), 582–590. https://doi.org/10.1111/jcpp.12008.

    Article  PubMed  PubMed Central  Google Scholar 

  • Herlihy, L., Knoch, K., Vibert, B., & Fein, D. (2013). Parents’ first concerns about toddlers with autism spectrum disorder: Effect of sibling status. Autism. https://doi.org/10.1177/1362361313509731.

  • Jones, W., & Klin, A. (2013). Attention to eyes is present but in decline in 2–6-month-old infants later diagnosed with autism. Nature, 504(7480), 427–431. https://doi.org/10.1038/nature12715.

    Article  PubMed  PubMed Central  Google Scholar 

  • Kleinman, J. M., Ventola, P. E., Pandey, J., Verbalis, A. D., Barton, M., Hodgson, S., et al. (2008). Diagnostic stability in very young children with autism spectrum disorders. Journal of Autism and Developmental Disorders, 38(4), 606–615. https://doi.org/10.1007/s10803-007-0427-8.

    Article  PubMed  Google Scholar 

  • Le Couteur, A., Lord, C., & Rutter, M. (2003). The autism diagnostic interview-revised (ADI-R). Los Angeles: Western Psychological Services.

    Google Scholar 

  • Lord, C., Risi, S., Lambrecht, L., Cook, E. H., Leventhal, B. L., DiLavore, P. C., et al. (2000). The autism diagnostic observation schedule—Generic: A standard measure of social and communication deficits associated with the spectrum of autism. Journal of Autism and Developmental Disorders, 30(3), 205–223.

    Article  PubMed  Google Scholar 

  • Makrygianni, M. K., & Reed, P. (2010). A meta-analytic review of the effectiveness of behavioural early intervention programs for children with autistic spectrum disorders. Research in Autism Spectrum Disorders, 4(4), 577–593. https://doi.org/10.1016/j.rasd.2010.01.014.

    Article  Google Scholar 

  • Matson, J. L., Boisjoli, J. A., Hess, J. A., & Wilkins, J. (2010). Factor structure and diagnostic fidelity of the baby and infant screen for children with aUtIsm traits–part 1 (BISCUIT–part 1). Developmental Neurorehabilitation, 13(2), 72–79. https://doi.org/10.3109/17518420903213576.

    Article  PubMed  Google Scholar 

  • Matson, J. L., Boisjoli, J. A., & Wilkins, J. (2007). The baby and infant screen for children with aUtIsm traits (BISCUIT). Baton Rouge: Disability Consultants, LLC.

    Google Scholar 

  • Matson, J. L., & Horovitz, M. (2010). Stability of autism Spectrum disorders symptoms over time. Journal of Developmental and Physical Disabilities, 22(4), 331–342. https://doi.org/10.1007/s10882-010-9188-y.

    Article  Google Scholar 

  • Matson, J. L., Wilkins, J., & Fodstad, J. C. (2011). The validity of the baby and infant screen for children with aUtIsm traits: Part 1 (BISCUIT: Part 1). Journal of Autism and Developmental Disorders, 41(9), 1139–1146. https://doi.org/10.1007/s10803-010-0973-3.

    Article  PubMed  Google Scholar 

  • Matson, J. L., Wilkins, J., Sevin, J. A., Knight, C., Boisjoli, J. A., & Sharp, B. (2009a). Reliability and item content of the baby and infant screen for children with aUtIsm traits (BISCUIT): Parts 1–3. Research in Autism Spectrum Disorders, 3(2), 336–344. https://doi.org/10.1016/j.rasd.2008.08.001.

    Article  Google Scholar 

  • Matson, J. L., Wilkins, J., Sharp, B., Knight, C., Sevin, J. A., & Boisjoli, J. A. (2009b). Sensitivity and specificity of the baby and infant screen for children with aUtIsm traits (BISCUIT): Validity and cutoff scores for autism and PDD-NOS in toddlers. Research in Autism Spectrum Disorders, 3(4), 924–930. https://doi.org/10.1016/j.rasd.2009.04.001.

    Article  Google Scholar 

  • Moore, V., & Goodson, S. (2003). How well does early diagnosis of autism stand the test of time? Follow-up study of children assessed for autism at age 2 and development of an early diagnostic service. Autism, 7(1), 47–63. https://doi.org/10.1177/1362361303007001005.

    PubMed  Google Scholar 

  • Reichow, B., & Wolery, M. (2009). Comprehensive synthesis of early intensive behavioral interventions for young children with autism based on the UCLA young autism project model. Journal of Autism and Developmental Disorders, 39(1), 23–41. https://doi.org/10.1007/s10803-008-0596-0.

    Article  PubMed  Google Scholar 

  • Robins, D. L., Fein, D., Barton, M. L., & Green, J. A. (2001). The modified checklist for autism in toddlers: An initial study investigating the early detection of autism and pervasive developmental disorders. Journal of Autism and Developmental Disorders, 31(2), 131–144.

    Article  PubMed  Google Scholar 

  • Rogers, S. J. (2009). What are infant siblings teaching us about autism in infancy? Autism Research, 2(3), 125–137. https://doi.org/10.1002/aur.81.

    Article  PubMed  PubMed Central  Google Scholar 

  • Stone, W. L., Lee, E. B., Ashford, L., Brissie, J., Hepburn, S. L., Coonrod, E. E., & et al. (1999). Can autism be diagnosed accurately in children under 3 years? Journal of Child Psychology and Psychiatry, 40(2), 219–226.

  • Toth, K., Munson, J., Meltzoff, A. N., & Dawson, G. (2006). Early predictors of communication development in young children with autism spectrum disorder: Joint attention, imitation, and toy play. Journal of Autism and Developmental Disorders, 36(8), 993–1005. https://doi.org/10.1007/s10803-006-0137-7.

    Article  PubMed  PubMed Central  Google Scholar 

  • Virués-Ortega, J. (2010). Applied behavior analytic intervention for autism in early childhood: Meta-analysis, meta-regression and dose–response meta-analysis of multiple outcomes. Clinical Psychology Review, 30(4), 387–399. https://doi.org/10.1016/j.cpr.2010.01.008.

    Article  PubMed  Google Scholar 

  • Wiggins, L., Baio, J., & Rice, C. (2006). Examination of the time between first evaluation and first autism Spectrum diagnosis in a population-based sample. Journal of Developmental & Behavioral Pediatrics, 27(2), S79–S87.

    Article  Google Scholar 

  • Woolfenden, S., Sarkozy, V., Ridley, G., & Williams, K. (2012). A systematic review of the diagnostic stability of autism spectrum disorder. Research in Autism Spectrum Disorders, 6(1), 345–354. https://doi.org/10.1016/j.rasd.2011.06.008.

    Article  Google Scholar 

  • Worley, J. A., Matson, J. L., Mahan, S., Kozlowski, A. M., & Neal, D. (2011). Stability of symptoms of autism spectrum disorders in toddlers: An examination using the baby and infant screen for children with aUtIsm traits–part 1 (BISCUIT). Developmental Neurorehabilitation, 14(1), 36–40. https://doi.org/10.3109/17518423.2010.530638.

    Article  PubMed  Google Scholar 

  • Zwaigenbaum, L., Bauman, M. L., Choueiri, R., Kasari, C., Carter, A., Granpeesheh, D., … Natowicz, M. R. (2015). Early intervention for children with autism spectrum disorder under 3 years of age: Recommendations for practice and research. Pediatrics, 136(supplement), S60–S81. https://doi.org/10.1542/peds.2014-3667E.

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Correspondence to Xinrui Jiang.

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Funding

This study did not receive external funding.

Ethical Approval

The study was approved by the Louisiana State University Institutional Review Board and the State of Louisiana’s Department of Health and Hospitals Institutional Review Board. All procedures performed in the current study were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

Informed Consent

The use of data from EarlySteps was approved by OCDD of the State of Louisiana. Personal identifiers of each participant, including name and date of birth, were removed by the Louisiana Department of Health before receipt of the database.

Conflict of Interest

Deann Matson, Dr. Johnny Matson’s wife, is the sole owner of the Baby and Infant Screen for Children with aUtism Traits (BISCUIT) and sells the scale.

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Jiang, X., Matson, J.L., Issarraras, A. et al. Stability of Autism Symptoms in Young Children. J Dev Phys Disabil 29, 955–967 (2017). https://doi.org/10.1007/s10882-017-9567-8

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