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Does Hope Matter? Associations Among Self-Reported Hope, Anxiety, and Health-Related Quality of Life in Children and Adolescents with Cancer

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Abstract

This study aimed to examine the direct and indirect effects of hope on health-related quality of life (HRQoL) via anxiety of children/adolescents with cancer. We proposed to test if the mediation model was moderated by the child/adolescent’s treatment status. The participants were 211 children/adolescents diagnosed with cancer, divided into two clinical groups according to treatment status: 97 patients on-treatment and 114 off-treatment. Self-reported questionnaires measured the youths’ hope, anxiety, and HRQoL perceptions. The results revealed that children/adolescents on- and off-treatment only differed in levels of HRQoL, with a more compromised HRQoL found for the on-treatment group. Hope was positively associated with HRQoL, directly and indirectly via anxiety reduction. Moreover, only the association between anxiety and HRQoL was moderated by clinical group, revealing stronger associations for on-treatment patients. Findings highlight the importance of hope as a decisive resource in pediatric cancer adaptation, which may be strategically targeted in psycho-oncological interventions.

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Acknowledgements

The authors would like to thank the families and the health staff of the pediatric wards of two Portuguese state hospitals, namely, the Portuguese Institute of Oncology (IPO-Porto) and the Pediatric Unit-Coimbra Hospital and University Centre.

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  1. Faculty of Psychology and Educational Sciences, University of Coimbra, Rua do Colégio Novo, Apartado 6153, 3001-802, Coimbra, Portugal

    Ana Rita Martins, Susana Santos, Carlos Carona & Maria Cristina Canavarro

  2. Faculty of Psychology, University of Lisboa, Lisbon, Portugal

    Carla Crespo & Ágata Salvador

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  1. Ana Rita Martins
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Correspondence to Ana Rita Martins or Carla Crespo.

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Ana Rita Martins, Carla Crespo, Ágata Salvador, Susana Santos, Carlos Carona, and Maria Cristina Canavarro declare that they have no conflicts of interest.

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Martins, A.R., Crespo, C., Salvador, Á. et al. Does Hope Matter? Associations Among Self-Reported Hope, Anxiety, and Health-Related Quality of Life in Children and Adolescents with Cancer. J Clin Psychol Med Settings 25, 93–103 (2018). https://doi.org/10.1007/s10880-018-9547-x

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