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Psychological Factors that Link Socioeconomic Status to Depression/Anxiety in Patients with Systemic Lupus Erythematosus

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Abstract

Our analyses examined whether reserve capacity factors would explain the relationship between socioeconomic status (SES) and symptoms of depression/anxiety in patients with systemic lupus erythematosus (SLE). We assessed disease activity, depression/anxiety symptoms, and intrapersonal and interpersonal reserve capacity measures in 128 patients with SLE. Multiple meditational analyses revealed that intrapersonal and interpersonal psychosocial aspects of reserve capacity fully mediated the relationship between SES and depression/anxiety. Lower SES was indirectly associated with higher symptoms of depression and anxiety through the effects of psychosocial resilience. Interventions aimed at improving modifiable reserve capacity variables, such as self-esteem and optimism, may improve anxious/depressive symptomatology in patients with SLE.

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Acknowledgements

The authors thank Ester G. Penserga for directing this project and for her support. Geraldine Zamora-Racaza was supported by a Fellowship grant from the Asia Pacific League of Associations for Rheumatology for year 2013.

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Correspondence to Desiree R. Azizoddin.

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Desiree R. Azizoddin, Geraldine Zamora-Racaza, Sarah R. Ormseth, Lekeisha A. Sumner, Chelsie Cost, Julia R. Ayeroff, Michael H. Weisman, and Perry M. Nicassio declare they have no conflict of interest.

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All procedures performed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional and national) with the Helsinki declaration of 1975, as revised in 2000, and later amendments or comparable ethical standards. Informed consent was obtained from all individual participants included in the study.

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Azizoddin, D.R., Zamora-Racaza, G., Ormseth, S.R. et al. Psychological Factors that Link Socioeconomic Status to Depression/Anxiety in Patients with Systemic Lupus Erythematosus. J Clin Psychol Med Settings 24, 302–315 (2017). https://doi.org/10.1007/s10880-017-9505-z

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