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Longitudinal Results of Cognitive Behavioral Treatment for Youths with Inflammatory Bowel Disease and Depressive Symptoms

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Abstract

Youths with chronic physical illnesses face increased rates of psychological problems and the burden of coping with physical illness-related challenges. The following data describes treatment outcome maintenance results from a randomized clinical trial investigating the impact of a cognitive behavioral intervention Primary and Secondary Control Enhancement Therapy-Physical Illness (PASCET-PI) as compared to treatment as usual (TAU) on youths with inflammatory bowel disease (IBD). Forty-one participants aged 11–17 with IBD and concurrent depressive symptomatology were randomized to PASCET-PI (n = 22) or TAU (n = 19). Self-reported depressive features, global functioning, and DSM-IV depressive symptomatology were assessed immediately post-treatment (T2), followed by assessments at 6-months (T3) and 12-months (T4) post-treatment initiation. Repeated measure models revealed significantly improved global psychosocial functioning in youths randomized to PASCET-PI compared to youths randomized to TAU. Improvements in self-reported depressive features and DSM-IV depressive symptoms were found at the trend level for youths randomized to PASCET-PI relative to those receiving TAU. Effect size estimates for all outcome variables suggested large to medium treatment effects.

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Acknowledgments

We would like to thank Elyse Kenney for her efforts in recruiting study participants and administering the follow-up assessments. Without her assistance, this project would not have been possible. This work was supported by Grant No. MH064604 from the National Institutes of Health and the Wolpow Family Fund.

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The authors have no conflicts of interest to disclose.

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Correspondence to Eva Szigethy.

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Thompson, R.D., Craig, A., Crawford, E.A. et al. Longitudinal Results of Cognitive Behavioral Treatment for Youths with Inflammatory Bowel Disease and Depressive Symptoms. J Clin Psychol Med Settings 19, 329–337 (2012). https://doi.org/10.1007/s10880-012-9301-8

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