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Gepubliceerd in:

01-12-2014

Chronic pain and cardiovascular stress responses in a general population: the Tromsø Study

Auteurs: Roy Bjørkholt Olsen, Stephen Bruehl, Christopher Sivert Nielsen, Leiv Arne Rosseland, Anne Elise Eggen, Audun Stubhaug

Gepubliceerd in: Journal of Behavioral Medicine | Uitgave 6/2014

Abstract

We tested whether cardiovascular stress responsiveness is elevated in individuals experiencing chronic pain in a large general population sample. Blood pressure (BP) and heart rate (HR) were assessed at rest, during the cold pressor test, and during subsequent recovery in 554 individuals reporting daily chronic pain and 3,082 individuals free of chronic pain. After correcting for potential confounds, differences as a function of chronic pain status were noted for only 5 of 23 cardiovascular outcomes despite very high statistical power. Compared to the pain-free group, the chronic pain group displayed higher baseline HR/mean arterial pressure (MAP) ratio (p = .03), greater systolic BP (SBP) reactivity during the cold pressor test (p = .04), and higher HR/MAP ratio (p = .047) and significantly less SBP (p = .017) and MAP (p = .041) return to baseline during recovery. Findings suggest that changes in cardiovascular stress responsiveness associated with chronic pain are of limited clinical significance and unlikely to contribute to increased cardiovascular risk in the chronic pain population.

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Titel: Chronic pain and cardiovascular stress responses in a general population: the Tromsø Study
Auteurs: Roy Bjørkholt Olsen
Stephen Bruehl
Christopher Sivert Nielsen
Leiv Arne Rosseland
Anne Elise Eggen
Audun Stubhaug
Publicatiedatum: 01-12-2014
Uitgeverij: Springer US
Gepubliceerd in: Journal of Behavioral Medicine / Uitgave 6/2014
Print ISSN: 0160-7715
Elektronisch ISSN: 1573-3521
DOI: https://doi.org/10.1007/s10865-014-9568-3

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