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Gepubliceerd in: Journal of Psychopathology and Behavioral Assessment 4/2018

10-05-2018

The Contribution of Worry Behaviors to the Diagnosis of Generalized Anxiety Disorder

Auteurs: Timothy A. Brown, Esther S. Tung

Gepubliceerd in: Journal of Psychopathology and Behavioral Assessment | Uitgave 4/2018

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Abstract

Worry behaviors (i.e., overt acts to avoid or cope with worry-induced distress) have been recognized as being important in the psychopathology and treatment of generalized anxiety disorder (GAD). This study evaluated the worry behaviors criterion proposed for DSM-5 GAD, but was ultimately not adopted due to insufficient evidence. In 800 outpatients with emotional disorders (366 with GAD), most patients with GAD (92.6%) met the proposed worry behaviors criterion, which was at a rate significantly higher than other patient groups (e.g., patients with mood disorders). Patients who met the worry behaviors criterion had more severe GAD than patients who did not. The worry behaviors criterion, and 3 of its 4 constituent behaviors, were associated with no better than “fair” interrater reliability. Diagnostic reliability of GAD was not improved in cases where both interviewers agreed the worry behaviors criterion was met. The worry behaviors criterion significantly predicted DSM-5 GAD holding core GAD features constant (e.g., excessive worry), but this contribution was weak and did not appreciably improve the classification accuracy of GAD diagnostic status. Mixed support was obtained for the discriminant validity of the worry behaviors criterion in relation to mood disorders. Raising the proposed threshold of the criterion (requiring 2 instead of 1 behaviors) did not result in a substantial improvement in reliability, prediction, and classification accuracy. Although additional research is warranted (e.g., importance of worry behaviors in the treatment and natural course of GAD), the results raise questions about the role of worry behaviors in the diagnostic classification of GAD.
Voetnoten
1
The No GAD and OSAD groups presented in Table 2 are not mutually exclusive because the No GAD group was comprised in part by patients who were assigned OSAD.
 
2
Because the ADIS-5 ratings of excessiveness of worry and uncontrollability of worry were highly correlated (r = .92), uncontrollability of worry was not included as a predictor in these analyses.
 
3
The worry behaviors criterion also remained a significant, albeit weak, predictor of GAD status when the presence/absence of a current mood disorder diagnosis was used as the depression covariate, OR = 2.72, LRT = 12.01, p < .001, ΔR2L = .01.
 
4
Although dimensional approaches to disorder classification (e.g., Brown and Barlow 2009) have been proposed in part to reduce measurement error associated with imposing categorical cut-offs on symptom features that operate in a continuous fashion (e.g., binary thresholds of symptom counts and severity in DSM-5 diagnoses), it is interesting to note that the interrater reliability of the dimensional and categorical ratings of the worry behaviors did not appreciably differ (see Table 1).
 
5
It is also noteworthy that “threshold” issues were a relatively less common reason for GAD disagreements (9%) in a study examining the sources of diagnostic unreliability of DSM-IV anxiety and mood disorders (Brown et al. 2001b).
 
Literatuur
go back to reference American Psychiatric Association. (1994). Diagnostic and statistical manual of mental disorders (4th ed.). Washington, DC: Author. American Psychiatric Association. (1994). Diagnostic and statistical manual of mental disorders (4th ed.). Washington, DC: Author.
go back to reference American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders (5th ed.). Washington, DC: Author.CrossRef American Psychiatric Association. (2013). Diagnostic and statistical manual of mental disorders (5th ed.). Washington, DC: Author.CrossRef
go back to reference Andrews, G., Hobbs, M. J., Borkovec, T. D., Beesdo, K., Craske, M. G., Heimberg, R. G., Rapee, R. M., Ruscio, A. M., & Stanley, M. A. (2010). Generalized worry disorder: A review of DSM-IV generalized anxiety disorder and options for DSM-V. Depression and Anxiety, 27, 134–147.CrossRef Andrews, G., Hobbs, M. J., Borkovec, T. D., Beesdo, K., Craske, M. G., Heimberg, R. G., Rapee, R. M., Ruscio, A. M., & Stanley, M. A. (2010). Generalized worry disorder: A review of DSM-IV generalized anxiety disorder and options for DSM-V. Depression and Anxiety, 27, 134–147.CrossRef
go back to reference Beesdo-Baum, K., Jenjahn, E., Höfler, M., Lueken, U., Becker, E. S., & Hoyer, J. (2012). Avoidance, safety behavior, and reassurance seeking in generalized anxiety disorder. Depression and Anxiety, 29, 948–957.CrossRef Beesdo-Baum, K., Jenjahn, E., Höfler, M., Lueken, U., Becker, E. S., & Hoyer, J. (2012). Avoidance, safety behavior, and reassurance seeking in generalized anxiety disorder. Depression and Anxiety, 29, 948–957.CrossRef
go back to reference Brown, T. A., & Barlow, D. H. (2002). Classification of anxiety and mood disorders. In D. H. Barlow (Ed.), Anxiety and its disorders: The nature and treatment of anxiety and panic (2nd ed., pp. 292–327). New York: Guilford Press. Brown, T. A., & Barlow, D. H. (2002). Classification of anxiety and mood disorders. In D. H. Barlow (Ed.), Anxiety and its disorders: The nature and treatment of anxiety and panic (2nd ed., pp. 292–327). New York: Guilford Press.
go back to reference Brown, T.A., & Barlow, D.H. (2009). A proposal for a dimensional classification system based on the shared features of the DSM-IV anxiety and mood disorders: Implications for assessment and treatment. Psychological Assessment, 21, 256–271.CrossRef Brown, T.A., & Barlow, D.H. (2009). A proposal for a dimensional classification system based on the shared features of the DSM-IV anxiety and mood disorders: Implications for assessment and treatment. Psychological Assessment, 21, 256–271.CrossRef
go back to reference Brown, T. A., & Barlow, D. H. (2014). Anxiety and Related Disorders Interview Schedule for DSM-5 (ADIS-5). New York: Oxford University Press. Brown, T. A., & Barlow, D. H. (2014). Anxiety and Related Disorders Interview Schedule for DSM-5 (ADIS-5). New York: Oxford University Press.
go back to reference Brown, T. A., Barlow, D. H., & Liebowitz, M. R. (1994). The empirical basis of generalized anxiety disorder. American Journal of Psychiatry, 151, 1272–1280 tz.CrossRef Brown, T. A., Barlow, D. H., & Liebowitz, M. R. (1994). The empirical basis of generalized anxiety disorder. American Journal of Psychiatry, 151, 1272–1280 tz.CrossRef
go back to reference Brown, T. A., Marten, P. A., & Barlow, D. H. (1995). Discriminant validity of the symptoms constituting the DSM-III-R and DSM-IV associated symptom criterion of generalized anxiety disorder. Journal of Anxiety Disorders, 9, 317–328.CrossRef Brown, T. A., Marten, P. A., & Barlow, D. H. (1995). Discriminant validity of the symptoms constituting the DSM-III-R and DSM-IV associated symptom criterion of generalized anxiety disorder. Journal of Anxiety Disorders, 9, 317–328.CrossRef
go back to reference Brown, T. A., Chorpita, B. F., Korotitsch, W., & Barlow, D. H. (1997). Psychometric properties of the depression anxiety stress scales (DASS) in clinical samples. Behaviour Research and Therapy, 35, 79–89.CrossRef Brown, T. A., Chorpita, B. F., Korotitsch, W., & Barlow, D. H. (1997). Psychometric properties of the depression anxiety stress scales (DASS) in clinical samples. Behaviour Research and Therapy, 35, 79–89.CrossRef
go back to reference Brown, T. A., Chorpita, B. F., & Barlow, D. H. (1998). Structural relationships among dimensions of the DSM-IV anxiety and mood disorders and dimensions of negative affect, positive affect, and autonomic arousal. Journal of Abnormal Psychology, 107, 179–192.CrossRef Brown, T. A., Chorpita, B. F., & Barlow, D. H. (1998). Structural relationships among dimensions of the DSM-IV anxiety and mood disorders and dimensions of negative affect, positive affect, and autonomic arousal. Journal of Abnormal Psychology, 107, 179–192.CrossRef
go back to reference Brown, T. A., Campbell, L. A., Lehman, C. L., Grisham, J. R., & Mancill, R. B. (2001a). Current and lifetime comorbidity of the DSM-IV anxiety and mood disorders in a large clinical sample. Journal of Abnormal Psychology, 110, 585–599.CrossRef Brown, T. A., Campbell, L. A., Lehman, C. L., Grisham, J. R., & Mancill, R. B. (2001a). Current and lifetime comorbidity of the DSM-IV anxiety and mood disorders in a large clinical sample. Journal of Abnormal Psychology, 110, 585–599.CrossRef
go back to reference Brown, T. A., Di Nardo, P. A., Lehman, C. L., & Campbell, L. A. (2001b). Reliability of DSM-IV anxiety and mood disorders: Implications for the classification of emotional disorders. Journal of Abnormal Psychology, 110, 49–58.CrossRef Brown, T. A., Di Nardo, P. A., Lehman, C. L., & Campbell, L. A. (2001b). Reliability of DSM-IV anxiety and mood disorders: Implications for the classification of emotional disorders. Journal of Abnormal Psychology, 110, 49–58.CrossRef
go back to reference Coleman, S. L., Pieterfesa, A. S., Holaway, R. M., Coles, M. E., & Heimberg, R. G. (2011). Content and correlates of checking related to symptoms of obsessive-compulsive disorder and generalized anxiety disorder. Journal of Anxiety Disorders, 25, 293–301.CrossRef Coleman, S. L., Pieterfesa, A. S., Holaway, R. M., Coles, M. E., & Heimberg, R. G. (2011). Content and correlates of checking related to symptoms of obsessive-compulsive disorder and generalized anxiety disorder. Journal of Anxiety Disorders, 25, 293–301.CrossRef
go back to reference Di Nardo, P. A., O’Brien, G. T., Barlow, D. H., Waddell, M. T., & Blanchard, E. B. (1983). Reliability of the DSM-III anxiety disorder categories using a new structured interview. Archives of General Psychiatry, 40, 1070–1074.CrossRef Di Nardo, P. A., O’Brien, G. T., Barlow, D. H., Waddell, M. T., & Blanchard, E. B. (1983). Reliability of the DSM-III anxiety disorder categories using a new structured interview. Archives of General Psychiatry, 40, 1070–1074.CrossRef
go back to reference Dugas, M. J., Gagnon, F., Ladouceur, R., & Freeston, M. H. (1998). Generalized anxiety disorder: A preliminary test of a conceptual model. Behaviour Research and Therapy, 36, 215–226.CrossRef Dugas, M. J., Gagnon, F., Ladouceur, R., & Freeston, M. H. (1998). Generalized anxiety disorder: A preliminary test of a conceptual model. Behaviour Research and Therapy, 36, 215–226.CrossRef
go back to reference Fleiss, J. L., Nee, J. C. M., & Landis, J. R. (1979). Large sample variance of kappa in the case of different sets of raters. Psychological Bulletin, 86, 974–977.CrossRef Fleiss, J. L., Nee, J. C. M., & Landis, J. R. (1979). Large sample variance of kappa in the case of different sets of raters. Psychological Bulletin, 86, 974–977.CrossRef
go back to reference Kessler, R. C., Gruber, M., Hettema, J. M., Hwang, I., Sampson, N., & Yonkers, K. A. (2008). Comorbid major depression and generalized anxiety disorders in the National Comorbidity Survey follow-up. Psychological Medicine, 38, 365–374.PubMed Kessler, R. C., Gruber, M., Hettema, J. M., Hwang, I., Sampson, N., & Yonkers, K. A. (2008). Comorbid major depression and generalized anxiety disorders in the National Comorbidity Survey follow-up. Psychological Medicine, 38, 365–374.PubMed
go back to reference Lawrence, A. E., & Brown, T. A. (2009). Differentiating generalized anxiety disorder from anxiety disorder not otherwise specified. Journal of Nervous and Mental Disease, 197(12), 879–886.CrossRef Lawrence, A. E., & Brown, T. A. (2009). Differentiating generalized anxiety disorder from anxiety disorder not otherwise specified. Journal of Nervous and Mental Disease, 197(12), 879–886.CrossRef
go back to reference Lovibond, P. F., & Lovibond, S. H. (1995). The structure of negative emotional states: Comparison of the depression anxiety stress scales (DASS) with the Beck depression and anxiety inventories. Behaviour Research and Therapy, 33, 335–342.CrossRef Lovibond, P. F., & Lovibond, S. H. (1995). The structure of negative emotional states: Comparison of the depression anxiety stress scales (DASS) with the Beck depression and anxiety inventories. Behaviour Research and Therapy, 33, 335–342.CrossRef
go back to reference Mahoney, A. E., Hobbs, M. J., Newby, J. M., Williams, A. D., Sunderland, M., & Andrews, G. (2016). The worry behaviors inventory: Assessing behavioral avoidance associated with generalized anxiety disorder. Journal of Affective Disorders, 203, 256–264.CrossRef Mahoney, A. E., Hobbs, M. J., Newby, J. M., Williams, A. D., Sunderland, M., & Andrews, G. (2016). The worry behaviors inventory: Assessing behavioral avoidance associated with generalized anxiety disorder. Journal of Affective Disorders, 203, 256–264.CrossRef
go back to reference Mannuzza, S., Fyer, A. J., Martin, L. Y., Gallops, M. S., Endicott, J., Gorman, J. M., Liebowitz, M. R., & Klein, D. F. (1989). Reliability of anxiety assessment: I. Diagnostic agreement. Archives of General Psychiatry, 46, 1093–1101.CrossRef Mannuzza, S., Fyer, A. J., Martin, L. Y., Gallops, M. S., Endicott, J., Gorman, J. M., Liebowitz, M. R., & Klein, D. F. (1989). Reliability of anxiety assessment: I. Diagnostic agreement. Archives of General Psychiatry, 46, 1093–1101.CrossRef
go back to reference Menard, S. (2002). Applied logistic regression analysis (2nd ed.). Thousand Oaks: Sage Publications.CrossRef Menard, S. (2002). Applied logistic regression analysis (2nd ed.). Thousand Oaks: Sage Publications.CrossRef
go back to reference Di Nardo, P.A., Moras, K., Barlow, D.H., Rapee, R.M., & Brown, T.A. (1993). Reliability of DSM-III-R anxiety disorder categories using the anxiety disorders interview schedule-revised (ADIS-R). Archives of General Psychiatry, 50, 251–256.CrossRef Di Nardo, P.A., Moras, K., Barlow, D.H., Rapee, R.M., & Brown, T.A. (1993). Reliability of DSM-III-R anxiety disorder categories using the anxiety disorders interview schedule-revised (ADIS-R). Archives of General Psychiatry, 50, 251–256.CrossRef
go back to reference Newman, M. G., & Llera, S. J. (2011). A novel theory of experiential avoidance in generalized anxiety disorder: A review and synthesis of research supporting a contrast avoidance model of worry. Clinical Psychology Review, 31, 371–382.CrossRef Newman, M. G., & Llera, S. J. (2011). A novel theory of experiential avoidance in generalized anxiety disorder: A review and synthesis of research supporting a contrast avoidance model of worry. Clinical Psychology Review, 31, 371–382.CrossRef
go back to reference Regier, D. A., Narrow, W. E., Clarke, D. E., Kraemer, H. C., Kuramoto, S. J., Kuhl, E. A., & Kupfer, D. J. (2013). DSM-5 field trials in the United States and Canada, part II: Test-retest reliability of selected categorical diagnoses. American Journal of Psychiatry, 170, 59–70.CrossRef Regier, D. A., Narrow, W. E., Clarke, D. E., Kraemer, H. C., Kuramoto, S. J., Kuhl, E. A., & Kupfer, D. J. (2013). DSM-5 field trials in the United States and Canada, part II: Test-retest reliability of selected categorical diagnoses. American Journal of Psychiatry, 170, 59–70.CrossRef
go back to reference Rutter, L. A., & Brown, T. A. (2017). Psychometric properties of the generalized anxiety disorder scale – 7 (GAD-7) in outpatients with anxiety and mood disorders. Journal of Psychopathology and Behavioral Assessment, 39, 140–146.CrossRef Rutter, L. A., & Brown, T. A. (2017). Psychometric properties of the generalized anxiety disorder scale – 7 (GAD-7) in outpatients with anxiety and mood disorders. Journal of Psychopathology and Behavioral Assessment, 39, 140–146.CrossRef
go back to reference Schut, A. J., Castonguay, L. G., & Borkovec, T. D. (2001). Compulsive checking behaviors in generalized anxiety disorder. Journal of Clinical Psychology, 57, 705–715.CrossRef Schut, A. J., Castonguay, L. G., & Borkovec, T. D. (2001). Compulsive checking behaviors in generalized anxiety disorder. Journal of Clinical Psychology, 57, 705–715.CrossRef
go back to reference Spitzer, R. L., Kroenke, K., Williams, J. B., & Löwe, B. (2006). A brief measure for assessing generalized anxiety disorder. Archives of Internal Medicine, 166, 1092–1097.CrossRef Spitzer, R. L., Kroenke, K., Williams, J. B., & Löwe, B. (2006). A brief measure for assessing generalized anxiety disorder. Archives of Internal Medicine, 166, 1092–1097.CrossRef
go back to reference Starcevic, V., Portman, M. E., & Beck, A. T. (2012). Generalized anxiety disorder: Between neglect and epidemic. Journal of Nervous and Mental Disease, 200, 664–667.CrossRef Starcevic, V., Portman, M. E., & Beck, A. T. (2012). Generalized anxiety disorder: Between neglect and epidemic. Journal of Nervous and Mental Disease, 200, 664–667.CrossRef
go back to reference Steiger, J. H. (1980). Tests for comparing elements of a correlation matrix. Psychological Bulletin, 87, 245–251.CrossRef Steiger, J. H. (1980). Tests for comparing elements of a correlation matrix. Psychological Bulletin, 87, 245–251.CrossRef
go back to reference Townsend, M. H., Weissbecker, K. A., Barbee, J. G., Peña, J. M., Snider, L. M., Tynes, L. L., Tynes, S. F., Boudoin, C., Green-Liebovitz, M. I., & Winstead, D. (1999). Compulsive behaviors in generalized anxiety disorder and obsessive-compulsive disorder. Journal of Nervous and Mental Disease, 187, 697–699.CrossRef Townsend, M. H., Weissbecker, K. A., Barbee, J. G., Peña, J. M., Snider, L. M., Tynes, L. L., Tynes, S. F., Boudoin, C., Green-Liebovitz, M. I., & Winstead, D. (1999). Compulsive behaviors in generalized anxiety disorder and obsessive-compulsive disorder. Journal of Nervous and Mental Disease, 187, 697–699.CrossRef
go back to reference Williams, J. B. W., Gibbon, M., First, M. B., Spitzer, R. L., Davies, M., Borus, J., Howes, M. J., Kane, J., Pope, H. G., Rounsaville, B., & Wittchen, H. (1992). The structured clinical interview for DSM-III-R (SCID): II. Multisite test-retest reliability. Archives of General Psychiatry, 49, 630–636.CrossRef Williams, J. B. W., Gibbon, M., First, M. B., Spitzer, R. L., Davies, M., Borus, J., Howes, M. J., Kane, J., Pope, H. G., Rounsaville, B., & Wittchen, H. (1992). The structured clinical interview for DSM-III-R (SCID): II. Multisite test-retest reliability. Archives of General Psychiatry, 49, 630–636.CrossRef
Metagegevens
Titel
The Contribution of Worry Behaviors to the Diagnosis of Generalized Anxiety Disorder
Auteurs
Timothy A. Brown
Esther S. Tung
Publicatiedatum
10-05-2018
Uitgeverij
Springer US
Gepubliceerd in
Journal of Psychopathology and Behavioral Assessment / Uitgave 4/2018
Print ISSN: 0882-2689
Elektronisch ISSN: 1573-3505
DOI
https://doi.org/10.1007/s10862-018-9683-5

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