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Gepubliceerd in: Journal of Autism and Developmental Disorders 11/2020

21-03-2020 | Original Paper

Executive Function in High-Functioning Autism Spectrum Disorder: A Meta-analysis of fMRI Studies

Auteurs: Zheng Zhang, Peng Peng, Delong Zhang

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 11/2020

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Abstract

Abnormalities in executive function (EF) are clinical markers for autism spectrum disorder (ASD). However, the neural mechanisms underlying abnormal EF in ASD remain unclear. This meta-analysis investigated the construct, abnormalities, and age-related changes of EF in ASD. Thirty-three fMRI studies of inhibition, updating, and switching in individuals with high-functioning ASD were included (n = 1114; age range 7–57 years). The results revealed that the EF construct in ASD could be unitary (i.e., common EF) in children/adolescents, but unitary and diverse (i.e., common EF and inhibition) in adults. Abnormalities in this EF construct were found across development in individuals with ASD in comparison with typically developing individuals. Implications and recommendations are discussed for EF theory and for practice in ASD.
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Metagegevens
Titel
Executive Function in High-Functioning Autism Spectrum Disorder: A Meta-analysis of fMRI Studies
Auteurs
Zheng Zhang
Peng Peng
Delong Zhang
Publicatiedatum
21-03-2020
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 11/2020
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-020-04461-z

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