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Journal of Autism and Developmental Disorders

Gepubliceerd in:

08-02-2018 | Original Paper

Sex-Differences in Children Referred for Assessment: An Exploratory Analysis of the Autism Mental Status Exam (AMSE)

Auteurs: Roald A. Øien, Sara M. Vambheim, Logan Hart, Anders Nordahl-Hansen, Craig Erickson, Logan Wink, Martin R. Eisemann, Frederick Shic, Fred R. Volkmar, David Grodberg

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 7/2018

Abstract

The autism mental status exam is an eight-item observational assessment that structures the way we observe and document signs and symptoms of ASD. Investigations of test performance indicate strong sensitivity and specificity using gold-standard assessment as reference standard. This study aims to explore potential sex differences in AMSE test performance and observations of 123 children referred for autism assessment. Results indicates more language deficits in females with ASD than in males with ASD and less sensory symptoms in females compared to males with ASD. The AMSE performance is similar in identifying ASD and non-ASD in females compared to males. Less disruptive behaviors in females, might cause a need for a bigger hit to other areas of development to raise concern.

vorige artikel Autism Spectrum Disorder in an Unselected Cohort of Children with Neurofibromatosis Type 1 (NF1)

volgende artikel A Systematic Review of Group Social Skills Interventions, and Meta-analysis of Outcomes, for Children with High Functioning ASD

American Psychiatric Association. (2014). Diagnostic and statistical manual of mental disorders. APA DSM.

Baron-Cohen, S. (2002). The extreme male brain theory of autism. Trends in Cognitive Sciences, 6(6), 248–254. https://doi.org/10.1016/S1364-6613(02)01904-6.CrossRefPubMed

Baron-Cohen, S. (2009). Autism: The empathizing-systemizing (E-S) theory. Annals of the New York Academy of Sciences, 1156(1), 68–80. https://doi.org/10.1111/j.1749-6632.2009.04467.x.CrossRefPubMed

Bolte, S., Duketis, E., Poustka, F., & Holtmann, M. (2011). Sex differences in cognitive domains and their clinical correlates in higher-functioning autism spectrum disorders. Autism, 15(4), 497–511. https://doi.org/10.1177/1362361310391116.CrossRefPubMed

Carter, A. S., Black, D. O., Tewani, S., Connolly, C. E., Kadlec, M. B., & Tager-Flusberg, H. (2007). Sex differences in toddlers with autism spectrum disorders. Journal of Autism and Developmental Disorders, 37(1), 86–97. https://doi.org/10.1007/s10803-006-0331-7.CrossRefPubMed

Cohen, J. (1988). Statistical power analysis for the behavioral sciences (2^nd ed.). New York: Routledge.

Dean, M., Harwood, R., & Kasari, C. (2017). The art of camouflage: Gender differences in the social behaviors of girls and boys with autism spectrum disorder. Autism, 21(6), 678–689.CrossRefPubMed

Dworzynski, K., Ronald, A., Bolton, P., & Happé, F. (2012). How different are girls and boys above and below the diagnostic threshold for autism spectrum disorders? Journal of the American Academy of Child and Adolescent Psychiatry, 51(8), 788–797. https://doi.org/10.1016/j.jaac.2012.05.018.CrossRefPubMed

Elsabbagh, M., Divan, G., Koh, Y.-J., Kim, Y. S., Kauchali, S., Marcín, C., et al. (2012). Global prevalence of autism and other pervasive developmental disorders. Autism Research, 5(3), 160–179. https://doi.org/10.1002/aur.239.CrossRefPubMedPubMedCentral

Fombonne, E. (2003). Epidemiological surveys of autism and other pervasive developmental disorders: An update. Journal of Autism and Developmental Disorders, 33(4), 365–382. https://doi.org/10.1023/A:1025054610557.CrossRefPubMed

Fombonne, E., Quirke, S., & Hagen, A. (2011). Epidemiology of pervasive developmental disorders. Autism spectrum disorders (pp. 90–111). Oxford: Oxford University Press. https://doi.org/10.1093/med/9780195371826.003.0007.CrossRef

Frazier, T. W., Georgiades, S., Bishop, S. L., & Hardan, A. Y. (2014). Behavioral and cognitive characteristics of females and males with autism in the Simons simplex collection. Journal of the American Academy of Child and Adolescent Psychiatry, 53(3), 329–340.e3. https://doi.org/10.1016/j.jaac.2013.12.004.CrossRefPubMed

Gilman, S. R., Iossifov, I., Levy, D., Ronemus, M., Wigler, M., & Vitkup, D. (2011). Rare de novo variants associated with autism implicate a large functional network of genes involved in formation and function of synapses. Neuron, 70(5), 898–907. https://doi.org/10.1016/j.neuron.2011.05.021.CrossRefPubMedPubMedCentral

Grodberg, D., Weinger, P. M., Halpern, D., Parides, M., Kolevzon, A., & Buxbaum, J. D. (2014). The autism mental status exam: Sensitivity and specificity using DSM-5 criteria for autism spectrum disorder in verbally fluent adults. Journal of Autism and Developmental Disorders, 44(3), 609–614. https://doi.org/10.1007/s10803-013-1917-5.CrossRefPubMedPubMedCentral

Grodberg, D., Weinger, P. M., Kolevzon, A., Soorya, L., & Buxbaum, J. D. (2012). Brief report: The autism mental status examination: Development of a brief autism-focused exam. Journal of Autism and Developmental Disorders, 42(3), 455–459. https://doi.org/10.1007/s10803-011-1255-4.CrossRefPubMed

Halpern, D. F. (1997). Sex differences in intelligence: Implications for education. American Psychologist, 52(10), 1091–1102. https://doi.org/10.1037/0003-066X.52.10.1091.CrossRefPubMed

Hartley, S. L., & Sikora, D. M. (2009). Sex differences in autism spectrum disorder: An examination of developmental functioning, autistic symptoms, and coexisting behavior problems in toddlers. Journal of Autism and Developmental Disorders, 39(12), 1715–1722. https://doi.org/10.1007/s10803-009-0810-8.CrossRefPubMedPubMedCentral

Hattier, M. A., Matson, J. L., Tureck, K., & Horovitz, M. (2011). The effects of gender and age on repetitive and/or restricted behaviors and interests in adults with autism spectrum disorders and intellectual disability. Research in Developmental Disabilities, 32(6), 2346–2351. https://doi.org/10.1016/j.ridd.2011.07.028.CrossRefPubMed

Head, A. M., McGillivray, J. A., & Stokes, M. A. (2014). Gender differences in emotionality and sociability in children with autism spectrum disorders. Autism, 5, 19.

Koenig, K., & Tsatsanis, K. D. (2005). Pervasive developmental disorders in girls. In Handbook of behavioral and emotional problems in girls (pp. 211–237). Boston, MA: Springer. https://doi.org/10.1007/0-306-48674-1_7.CrossRef

Kopp, S., & Gillberg, C. (2011). The Autism Spectrum Screening Questionnaire (ASSQ)-revised extended version (ASSQ-REV): An instrument for better capturing the autism phenotype in girls? A preliminary study involving 191 clinical cases and community controls. Research in Developmental Disabilities, 32(6), 2875–2888. https://doi.org/10.1016/j.ridd.2011.05.017.CrossRefPubMed

Lai, D.-C., Tseng, Y.-C., Hou, Y.-M., & Guo, H.-R. (2012). Gender and geographic differences in the prevalence of autism spectrum disorders in children: Analysis of data from the national disability registry of Taiwan. Research in Developmental Disabilities, 33(3), 909–915. https://doi.org/10.1016/j.ridd.2011.12.015.CrossRefPubMed

Loomes, R., Hull, L., & Mandy, W. P. L. (2017). What is the male-to-female ratio in autism spectrum disorder? A systematic review and meta-analysis. Journal of the American Academy of Child and Adolescent Psychiatry, 56(6), 466–474. https://doi.org/10.1016/j.jaac.2017.03.013.CrossRefPubMed

Mandy, W., Chilvers, R., Chowdhury, U., Salter, G., Seigal, A., & Skuse, D. (2012). Sex differences in autism spectrum disorder: Evidence from a large sample of children and adolescents. Journal of Autism and Developmental Disorders, 42(7), 1304–1313. https://doi.org/10.1007/s10803-011-1356-0.CrossRefPubMed

Mayes, S. D., & Calhoun, S. L. (2011). Impact of IQ, age, SES, gender, and race on autistic symptoms. Research in Autism Spectrum Disorders, 5(2), 749–757. https://doi.org/10.1016/j.rasd.2010.09.002.CrossRef

Øien, R. A., Hart, L., Schjølberg, S., Wall, C. A., Kim, E. S., Nordahl-Hansen, A., et al. (2017). Parent-endorsed sex differences in toddlers with and without ASD: Utilizing the M-CHAT. Journal of Autism and Developmental Disorders, 47(1), 126–134. https://doi.org/10.1007/s10803-016-2945-8.CrossRefPubMed

Øien, R. A., Siper, P., Kolevzon, A., & Grodberg, D. (2016). Detecting autism spectrum disorder in children with ADHD and social disability. Journal of Attention Disorders. https://doi.org/10.1177/1087054716642518.PubMed

Robinson, E. B., Lichtenstein, P., Anckarsäter, H., Happé, F., & Ronald, A. (2013). Examining and interpreting the female protective effect against autistic behavior. Proceedings of the National Academy of Sciences USA, 110(13), 5258–5262. https://doi.org/10.1073/pnas.1211070110.CrossRef

Salomone, E., Beranová, Š, Bonnet-Brilhault, F., Lauritsen, M. B., Budisteanu, M., Buitelaar, J., et al. (2015). Use of early intervention for young children with autism spectrum disorder across Europe. Autism, 20(2), 233–249. https://doi.org/10.1177/1362361315577218.CrossRefPubMed

Skuse, D. H. (2007). Rethinking the nature of genetic vulnerability to autistic spectrum disorders. Trends in Genetics, 23(8), 387–395. https://doi.org/10.1016/j.tig.2007.06.003.CrossRefPubMed

Solomon, M., Miller, M., Taylor, S. L., Hinshaw, S. P., & Carter, C. S. (2012). Autism symptoms and internalizing psychopathology in girls and boys with autism spectrum disorders. Journal of Autism and Developmental Disorders, 42(1), 48–59. https://doi.org/10.1007/s10803-011-1215-z.CrossRefPubMed

Szatmari, P., Liu, X.-Q., Goldberg, J., Zwaigenbaum, L., Paterson, A. D., Woodbury-Smith, M., et al. (2012). Sex differences in repetitive stereotyped behaviors in autism: Implications for genetic liability. American Journal of Medical Genetics Part B: Neuropsychiatric Genetics, 159B(1), 5–12. https://doi.org/10.1002/ajmg.b.31238.CrossRefPubMed

Volkmar, F. R., Szatmari, P., & Sparrow, S. S. (1993). Sex differences in pervasive developmental disorders. Journal of Autism and Developmental Disorders, 23(4), 579–591. https://doi.org/10.1007/BF01046103.CrossRefPubMed

Werling, D. M., & Geschwind, D. H. (2013). Sex differences in autism spectrum disorders. Current Opinion in Neurology, 26(2), 146–153. https://doi.org/10.1097/WCO.0b013e32835ee548.CrossRefPubMedPubMedCentral

Zahn-Waxler, C., Crick, N. R., Shirtcliff, E. A., & Woods, K. E. (2006). The origins and development of psychopathology in females and males. Hoboken: Wiley.

Zwaigenbaum, L., Bryson, S. E., Szatmari, P., Brian, J., Smith, I. M., Roberts, W., et al. (2012). Sex differences in children with autism spectrum disorder identified within a high-risk infant cohort. Journal of Autism and Developmental Disorders, 42(12), 2585–2596. https://doi.org/10.1007/s10803-012-1515-y.CrossRefPubMed

Titel: Sex-Differences in Children Referred for Assessment: An Exploratory Analysis of the Autism Mental Status Exam (AMSE)
Auteurs: Roald A. Øien
Sara M. Vambheim
Logan Hart
Anders Nordahl-Hansen
Craig Erickson
Logan Wink
Martin R. Eisemann
Frederick Shic
Fred R. Volkmar
David Grodberg
Publicatiedatum: 08-02-2018
Uitgeverij: Springer US
Gepubliceerd in: Journal of Autism and Developmental Disorders / Uitgave 7/2018
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI: https://doi.org/10.1007/s10803-018-3488-y

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