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Journal of Autism and Developmental Disorders

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17-10-2015 | Original Paper

Preserved Self-other Distinction During Empathy in Autism is Linked to Network Integrity of Right Supramarginal Gyrus

Auteurs: Ferdinand Hoffmann, Svenja Koehne, Nikolaus Steinbeis, Isabel Dziobek, Tania Singer

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 2/2016

Abstract

Autism spectrum disorder (ASD) shows deficits in self-other distinction during theory of mind (ToM). Here we investigated whether ASD patients also show difficulties in self-other distinction during empathy and if potential deficits are linked to dysfunctional resting-state connectivity patterns. In a first study, ASD patients and controls performed an emotional egocentricity paradigm and a ToM task. In the second study, resting-state connectivity of right temporo-parietal junction and right supramarginal gyrus (rSMG) were analysed using a large-scale fMRI data set. ASD patients exhibited deficient ToM but normal emotional egocentricity, which was paralleled by reduced connectivity of regions of the ToM network and unimpaired rSMG network connectivity. These results suggest spared self-other distinction during empathy and an intact rSMG network in ASD.

vorige artikel Sex Differences in Internalizing Problems During Adolescence in Autism Spectrum Disorder

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Titel: Preserved Self-other Distinction During Empathy in Autism is Linked to Network Integrity of Right Supramarginal Gyrus
Auteurs: Ferdinand Hoffmann
Svenja Koehne
Nikolaus Steinbeis
Isabel Dziobek
Tania Singer
Publicatiedatum: 17-10-2015
Uitgeverij: Springer US
Gepubliceerd in: Journal of Autism and Developmental Disorders / Uitgave 2/2016
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI: https://doi.org/10.1007/s10803-015-2609-0

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