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Journal of Autism and Developmental Disorders

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01-08-2014 | Brief Report

Brief Report: Evidence for Normative Resting-State Physiology in Autism

Auteurs: Heather J. Nuske, Giacomo Vivanti, Cheryl Dissanayake

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 8/2014

Abstract

Although the conception of autism as a disorder of abnormal resting-state physiology has a long history, the evidence remains mixed. Using state-of-the-art eye-tracking pupillometry, resting-state (tonic) pupil size was measured in children with and without autism. No group differences in tonic pupil size were found, and tonic pupil size was not related to age or cognitive ability in either group, and nor was it related to autistic symptoms. We suggest that previous findings of hyper-arousal in autism at baseline may be a product of different recording methods, in particular different movement-artifact removal techniques. These results question the notion that autism is associated with a fundamental dysregulation in resting-state physiology. Further research, employing such techniques is needed to confirm these findings.

vorige artikel Brief Report: Effects of Solution-Focused Brief Therapy Group-Work on Promoting Post-traumatic Growth of Mothers Who Have a Child with ASD

volgende artikel Brief Report: Generalisation of Word–Picture Relations in Children with Autism and Typically Developing Children

If cognitive ability is controlled for in this analysis, the results are unchanged; a univariate ANCOVA on baseline pupil diameter, controlling for cognitive ability (Mullen standard score), shows the groups are still indistinguishable on resting-state physiological activity F(1,43) = 0.02, p = 0.90, η ² < 0.001. The effect of the cognitive ability covariate was not significant F(1,43) < 0.001, p = 0.993, η ² < 0.001.

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Titel: Brief Report: Evidence for Normative Resting-State Physiology in Autism
Auteurs: Heather J. Nuske
Giacomo Vivanti
Cheryl Dissanayake
Publicatiedatum: 01-08-2014
Uitgeverij: Springer US
Gepubliceerd in: Journal of Autism and Developmental Disorders / Uitgave 8/2014
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI: https://doi.org/10.1007/s10803-014-2068-z

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