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Gepubliceerd in: Journal of Autism and Developmental Disorders 8/2013

01-08-2013 | Original Paper

Divergent Patterns of Social Cognition Performance in Autism and 22q11.2 Deletion Syndrome (22q11DS)

Auteurs: Kathryn L. McCabe, Jessica L. Melville, Dominique Rich, Paul A. Strutt, Gavin Cooper, Carmel M. Loughland, Ulrich Schall, Linda E. Campbell

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 8/2013

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Abstract

Individuals with developmental disorders frequently report a range of social cognition deficits including difficulties identifying facial displays of emotion. This study examined the specificity of face emotion processing deficits in adolescents with either autism or 22q11DS compared to typically developing (TD) controls. Two tasks (face emotion recognition and weather scene recognition) were used to explore group differences in visual scanpath strategy and concurrent recognition accuracy. For faces, the autism and 22q11DS groups demonstrated lower emotion recognition accuracy and fewer fixations compared to the TD group. Individuals with autism demonstrated fewer fixations to some weather scene stimuli compared to 22q11DS and TD groups, yet achieved a level of recognition accuracy comparable to the TD group. These findings provide evidence for a divergent pattern of social cognition dysfunction in autism and 22q11DS.
Literatuur
go back to reference American Psychiatric Association. (2000). Task force on dsm-iv: Dsm-iv-tr. Diagnostic and statistical manual of mental disorders. Washington, DC: American Psychiatric Association. American Psychiatric Association. (2000). Task force on dsm-iv: Dsm-iv-tr. Diagnostic and statistical manual of mental disorders. Washington, DC: American Psychiatric Association.
go back to reference Berument, S. K., Rutter, M., Lord, C., Pickles, A., & Bailey, A. (1999). Autism screening questionnaire: Diagnostic validity. The British Journal of Psychiatry: The Journal of Mental Science., 175, 444–451.CrossRef Berument, S. K., Rutter, M., Lord, C., Pickles, A., & Bailey, A. (1999). Autism screening questionnaire: Diagnostic validity. The British Journal of Psychiatry: The Journal of Mental Science., 175, 444–451.CrossRef
go back to reference Campbell, L., McCabe, K., Leadbeater, K., Schall, U., Loughland, C. M., & Rich, D. (2010). Visual scanning of faces in 22q11.2 deletion syndrome: Attention to the mouth or the eyes? Psychiatry Research, 177(1–2), 211–215.PubMedCrossRef Campbell, L., McCabe, K., Leadbeater, K., Schall, U., Loughland, C. M., & Rich, D. (2010). Visual scanning of faces in 22q11.2 deletion syndrome: Attention to the mouth or the eyes? Psychiatry Research, 177(1–2), 211–215.PubMedCrossRef
go back to reference Falck-Ytter, T., Fernell, E., Gillberg, C., & Von Hofsten, C. (2010). Face scanning distinguishes social from communication impairments in autism. Developmental Science, 13(6), 864–875.PubMedCrossRef Falck-Ytter, T., Fernell, E., Gillberg, C., & Von Hofsten, C. (2010). Face scanning distinguishes social from communication impairments in autism. Developmental Science, 13(6), 864–875.PubMedCrossRef
go back to reference Falck-Ytter, T., & von Hofsten, C. (2011). How special is social looking in ASD: A review. Progress in Brain Research, 189, 209–222.PubMedCrossRef Falck-Ytter, T., & von Hofsten, C. (2011). How special is social looking in ASD: A review. Progress in Brain Research, 189, 209–222.PubMedCrossRef
go back to reference Fine, S. E., Weissman, A., Gerdes, M., Pinto-Martin, J., Zackai, E. H., McDonald-McGinn, D. M., et al. (2005). Autism spectrum disorders and symptoms in children with molecularly confirmed 22q11.2 deletion syndrome. Journal of Autism and Developmental Disorders, 35(4), 461–470.PubMedCrossRef Fine, S. E., Weissman, A., Gerdes, M., Pinto-Martin, J., Zackai, E. H., McDonald-McGinn, D. M., et al. (2005). Autism spectrum disorders and symptoms in children with molecularly confirmed 22q11.2 deletion syndrome. Journal of Autism and Developmental Disorders, 35(4), 461–470.PubMedCrossRef
go back to reference First, M. B., Spitzer, R. L., Gibbon, M., & Williams, J. B. W. (2002). Structured clinical interview for dsm-iv-tr axis i disorders, research version, patient edition with psychotic screen (scid-i/p w/psy screen) New York, Biometrics Research. First, M. B., Spitzer, R. L., Gibbon, M., & Williams, J. B. W. (2002). Structured clinical interview for dsm-iv-tr axis i disorders, research version, patient edition with psychotic screen (scid-i/p w/psy screen) New York, Biometrics Research.
go back to reference Glaser, B., Debbane, M., Ottet, M. C., Vuilleumier, P., Zesiger, P., Antonarakis, S. E., et al. (2010). Eye gaze during face processing in children and adolescents with 22q11.2 deletion syndrome. Journal of the American Academy of Child and Adolescent Psychiatry, 49(7), 665–674.PubMed Glaser, B., Debbane, M., Ottet, M. C., Vuilleumier, P., Zesiger, P., Antonarakis, S. E., et al. (2010). Eye gaze during face processing in children and adolescents with 22q11.2 deletion syndrome. Journal of the American Academy of Child and Adolescent Psychiatry, 49(7), 665–674.PubMed
go back to reference Goldenberg, P. C., Calkins, M. E., Richard, J., McDonald-McGinn, D., Zackai, E., Mitra, N., et al. (2012). Computerized neurocognitive profile in young people with 22q11.2 deletion syndrome compared to youths with schizophrenia and at-risk for psychosis. American Journal of Medical Genetics. Pt B, Neuropsychiatric Genetics: the Official Publication of the International Society of Psychiatric Genetics, 159B(1), 87–93.CrossRef Goldenberg, P. C., Calkins, M. E., Richard, J., McDonald-McGinn, D., Zackai, E., Mitra, N., et al. (2012). Computerized neurocognitive profile in young people with 22q11.2 deletion syndrome compared to youths with schizophrenia and at-risk for psychosis. American Journal of Medical Genetics. Pt B, Neuropsychiatric Genetics: the Official Publication of the International Society of Psychiatric Genetics, 159B(1), 87–93.CrossRef
go back to reference Goodman, R., Ford, T., Simmons, H., Gatward, R., & Meltzer, H. (2000). Using the strengths and difficulties questionnaire (SDQ) to screen for child psychiatric disorders in a community sample. The British Journal of Psychiatry: The Journal of Mental Science., 177, 534–539.CrossRef Goodman, R., Ford, T., Simmons, H., Gatward, R., & Meltzer, H. (2000). Using the strengths and difficulties questionnaire (SDQ) to screen for child psychiatric disorders in a community sample. The British Journal of Psychiatry: The Journal of Mental Science., 177, 534–539.CrossRef
go back to reference Hobson, R. P., Ouston, J., & Lee, A. (1988). Emotion recognition in autism: Coordinating faces and voices. Psychological Medicine, 18(4), 911–923.PubMedCrossRef Hobson, R. P., Ouston, J., & Lee, A. (1988). Emotion recognition in autism: Coordinating faces and voices. Psychological Medicine, 18(4), 911–923.PubMedCrossRef
go back to reference Kaldy, Z., Kraper, C., Carter, A. S., & Blaser, E. (2011). Toddlers with autism spectrum disorder are more successful at visual search than typically developing toddlers. Developmental Science, 14(5), 980–988.PubMedCrossRef Kaldy, Z., Kraper, C., Carter, A. S., & Blaser, E. (2011). Toddlers with autism spectrum disorder are more successful at visual search than typically developing toddlers. Developmental Science, 14(5), 980–988.PubMedCrossRef
go back to reference Kates, W. R., Antshel, K. M., Fremont, W. P., Shprintzen, R. J., Strunge, L. A., Burnette, C. P., et al. (2007). Comparing phenotypes in patients with idiopathic autism to patients with velocardiofacial syndrome (22q11DS) with and without autism. American Journal of Medical Genetics. Pt A. 143A(22), 2642–2650. Kates, W. R., Antshel, K. M., Fremont, W. P., Shprintzen, R. J., Strunge, L. A., Burnette, C. P., et al. (2007). Comparing phenotypes in patients with idiopathic autism to patients with velocardiofacial syndrome (22q11DS) with and without autism. American Journal of Medical Genetics. Pt A. 143A(22), 2642–2650.
go back to reference Kaufman, J., Birmaher, B., Brent, D., Rao, U., Flynn, C., Moreci, P., et al. (1997). Schedule for affective disorders and schizophrenia for school-age children-present and lifetime version (K-SADS-PL): Initial reliability and validity data. Journal of the American Academy of Child and Adolescent Psychiatry, 36(7), 980–988.PubMedCrossRef Kaufman, J., Birmaher, B., Brent, D., Rao, U., Flynn, C., Moreci, P., et al. (1997). Schedule for affective disorders and schizophrenia for school-age children-present and lifetime version (K-SADS-PL): Initial reliability and validity data. Journal of the American Academy of Child and Adolescent Psychiatry, 36(7), 980–988.PubMedCrossRef
go back to reference Kemner, C., van Ewijk, L., van Engeland, H., & Hooge, I. (2008). Brief report: Eye movements during visual search tasks indicate enhanced stimulus discriminability in subjects with pdd. Journal of Autism and Developmental Disorders, 38(3), 553–557.PubMedCrossRef Kemner, C., van Ewijk, L., van Engeland, H., & Hooge, I. (2008). Brief report: Eye movements during visual search tasks indicate enhanced stimulus discriminability in subjects with pdd. Journal of Autism and Developmental Disorders, 38(3), 553–557.PubMedCrossRef
go back to reference Klin, A., Jones, W., Schultz, R., & Volkmar, F. (2003). The enactive mind, or from actions to cognition: Lessons from autism. Philosophical Transactions: Biological Sciences, 358(1430), 345–360.CrossRef Klin, A., Jones, W., Schultz, R., & Volkmar, F. (2003). The enactive mind, or from actions to cognition: Lessons from autism. Philosophical Transactions: Biological Sciences, 358(1430), 345–360.CrossRef
go back to reference Klin, A., Jones, W., Shultz, R., Volkmar, F., & Cohen, D. (2002). Visual fixation patterns during viewing of naturalistic social situations as predictors of social competence in individuals with autism. Archives of General Psychiatry, 59, 809–816.PubMedCrossRef Klin, A., Jones, W., Shultz, R., Volkmar, F., & Cohen, D. (2002). Visual fixation patterns during viewing of naturalistic social situations as predictors of social competence in individuals with autism. Archives of General Psychiatry, 59, 809–816.PubMedCrossRef
go back to reference Kuhlthau, K., Orlich, F., Hall, T. A., Sikora, D., Kovacs, E. A., Delahaye, J., et al. (2010). Health-related quality of life in children with autism spectrum disorders: Results from the autism treatment network. Journal of Autism and Developmental Disorders, 40(6), 721–729.PubMedCrossRef Kuhlthau, K., Orlich, F., Hall, T. A., Sikora, D., Kovacs, E. A., Delahaye, J., et al. (2010). Health-related quality of life in children with autism spectrum disorders: Results from the autism treatment network. Journal of Autism and Developmental Disorders, 40(6), 721–729.PubMedCrossRef
go back to reference McCabe, K., Rich, D., Loughland, C. M., Schall, U., & Campbell, L. E. (2011). Visual scanpath abnormalities in 22q11.2 deletion syndrome: Is this a face specific deficit? Psychiatry Research, 189(2), 292–298.PubMedCrossRef McCabe, K., Rich, D., Loughland, C. M., Schall, U., & Campbell, L. E. (2011). Visual scanpath abnormalities in 22q11.2 deletion syndrome: Is this a face specific deficit? Psychiatry Research, 189(2), 292–298.PubMedCrossRef
go back to reference Neumann, D., Spezio, M. L., Piven, J., & Adolphs, R. (2006). Looking you in the mouth: Abnormal gaze in autism resulting from impaired top-down modulation of visual attention. Social Cognitive and Affective Neuroscience, 1(3), 194–202.PubMedCrossRef Neumann, D., Spezio, M. L., Piven, J., & Adolphs, R. (2006). Looking you in the mouth: Abnormal gaze in autism resulting from impaired top-down modulation of visual attention. Social Cognitive and Affective Neuroscience, 1(3), 194–202.PubMedCrossRef
go back to reference Norbury, C. F., Brock, J., Cragg, L., Einav, S., Griffiths, H., & Nation, K. (2009). Eye-movement patterns are associated with communicative competence in autistic spectrum disorders. Journal of Child Psychology and Psychiatry, 50(7), 834–842.PubMedCrossRef Norbury, C. F., Brock, J., Cragg, L., Einav, S., Griffiths, H., & Nation, K. (2009). Eye-movement patterns are associated with communicative competence in autistic spectrum disorders. Journal of Child Psychology and Psychiatry, 50(7), 834–842.PubMedCrossRef
go back to reference O’Riordan, M. A. (2004). Superior visual search in adults with autism. Autism: The International Journal of Research and Practice., 8(3), 229–248.CrossRef O’Riordan, M. A. (2004). Superior visual search in adults with autism. Autism: The International Journal of Research and Practice., 8(3), 229–248.CrossRef
go back to reference Pierce, K., Conant, D., Hazin, R., Stoner, R., & Desmond, J. (2011). Preference for geometric patterns early in life as a risk factor for autism. Archives of General Psychiatry, 68, 101–109.PubMedCrossRef Pierce, K., Conant, D., Hazin, R., Stoner, R., & Desmond, J. (2011). Preference for geometric patterns early in life as a risk factor for autism. Archives of General Psychiatry, 68, 101–109.PubMedCrossRef
go back to reference Plaisted, K., O’Riordan, M., & Baron-Cohen, S. (1998). Enhanced discrimination of novel, highly similar stimuli by adults with autism during a perceptual learning task. Journal of Child Psychology and Psychiatry and Allied Disciplines, 39(5), 765–775.CrossRef Plaisted, K., O’Riordan, M., & Baron-Cohen, S. (1998). Enhanced discrimination of novel, highly similar stimuli by adults with autism during a perceptual learning task. Journal of Child Psychology and Psychiatry and Allied Disciplines, 39(5), 765–775.CrossRef
go back to reference Sasson, N. (2006). The development of face processing in autism. Journal of Autism and Developmental Disorders, 36(3), 381–394.PubMedCrossRef Sasson, N. (2006). The development of face processing in autism. Journal of Autism and Developmental Disorders, 36(3), 381–394.PubMedCrossRef
go back to reference Swillen, A., Devriendt, K., Legius, E., Eyskens, B., Dumoulin, M., Gewillig, M., et al. (1997). Intelligence and psychosocial adjustment in velocardiofacial syndrome: A study of 37 children and adolescents with vcfs. Journal of Medical Genetics, 34(6), 453–458.PubMedCrossRef Swillen, A., Devriendt, K., Legius, E., Eyskens, B., Dumoulin, M., Gewillig, M., et al. (1997). Intelligence and psychosocial adjustment in velocardiofacial syndrome: A study of 37 children and adolescents with vcfs. Journal of Medical Genetics, 34(6), 453–458.PubMedCrossRef
go back to reference Tottenham, N., Tanaka, J. W., Leon, A. C., McCarry, T., Nurse, M., Hare, T. A., et al. (2009). The nimstim set of facial expressions: Judgments from untrained research participants. Psychiatry Research, 168(3), 242–249.PubMedCrossRef Tottenham, N., Tanaka, J. W., Leon, A. C., McCarry, T., Nurse, M., Hare, T. A., et al. (2009). The nimstim set of facial expressions: Judgments from untrained research participants. Psychiatry Research, 168(3), 242–249.PubMedCrossRef
go back to reference Vorstman, J. A., Staal, W. G., van Daalen, E., van Engeland, H., Hochstenbach, P. F. and Franke, L. (2006). Identification of novel autism candidate regions through analysis of reported cytogenetic abnormalities associated with autism. Molecular Psychiatry 11(1), 1, 18–28. Vorstman, J. A., Staal, W. G., van Daalen, E., van Engeland, H., Hochstenbach, P. F. and Franke, L. (2006). Identification of novel autism candidate regions through analysis of reported cytogenetic abnormalities associated with autism. Molecular Psychiatry 11(1), 1, 18–28.
go back to reference Wechsler, D. (1999). Wechsler abbreviated scale of intelligence. San Antonio, TX: The Psychological Corporation. Wechsler, D. (1999). Wechsler abbreviated scale of intelligence. San Antonio, TX: The Psychological Corporation.
Metagegevens
Titel
Divergent Patterns of Social Cognition Performance in Autism and 22q11.2 Deletion Syndrome (22q11DS)
Auteurs
Kathryn L. McCabe
Jessica L. Melville
Dominique Rich
Paul A. Strutt
Gavin Cooper
Carmel M. Loughland
Ulrich Schall
Linda E. Campbell
Publicatiedatum
01-08-2013
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 8/2013
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-012-1742-2

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