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Gepubliceerd in: Journal of Autism and Developmental Disorders 5/2013

01-05-2013

Excess Mortality and Causes of Death in Autism Spectrum Disorders: A Follow up of the 1980s Utah/UCLA Autism Epidemiologic Study

Auteurs: Deborah Bilder, Elizabeth L. Botts, Ken R. Smith, Richard Pimentel, Megan Farley, Joseph Viskochil, William M. McMahon, Heidi Block, Edward Ritvo, Riva-Ariella Ritvo, Hilary Coon

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 5/2013

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Abstract

This study’s purpose was to investigate mortality among individuals with autism spectrum disorders (ASD) ascertained during a 1980s statewide autism prevalence study (n = 305) in relation to controls. Twenty-nine of these individuals (9.5 %) died by the time of follow up, representing a hazard rate ratio of 9.9 (95 % CI 5.7–17.2) in relation to population controls. Death certificates identified respiratory, cardiac, and epileptic events as the most common causes of death. The elevated mortality risk associated with ASD in the study cohort appeared related to the presence of comorbid medical conditions and intellectual disability rather than ASD itself suggesting the importance of coordinated medical care for this high risk sub-population of individuals with ASD.
Literatuur
go back to reference Baird, P. A., & Sadovnick, A. D. (1990). Underlying causes of death in Down syndrome: Accuracy of British Columbia death certificate data. Canadian Journal of Public Health, 81(6), 456–461. Baird, P. A., & Sadovnick, A. D. (1990). Underlying causes of death in Down syndrome: Accuracy of British Columbia death certificate data. Canadian Journal of Public Health, 81(6), 456–461.
go back to reference Bilder, D., Pinborough-Zimmerman, J., Miller, J., & McMahon, W. (2009). Prenatal, perinatal, and neonatal factors associated with autism spectrum disorders. Pediatrics, 123(5), 1293–1300.PubMedCrossRef Bilder, D., Pinborough-Zimmerman, J., Miller, J., & McMahon, W. (2009). Prenatal, perinatal, and neonatal factors associated with autism spectrum disorders. Pediatrics, 123(5), 1293–1300.PubMedCrossRef
go back to reference Centers for Disease Control and Prevention. (2009). Prevalence of autism spectrum disorders—Autism and developmental disabilities monitoring network, United States, 2006. Morbidity and Mortality Weekly Report, 58(10), 1–20. Centers for Disease Control and Prevention. (2009). Prevalence of autism spectrum disorders—Autism and developmental disabilities monitoring network, United States, 2006. Morbidity and Mortality Weekly Report, 58(10), 1–20.
go back to reference Danielsson, S., Gillberg, I. C., Billstedt, E., Gillberg, C., & Olsson, I. (2005). Epilepsy in young adults with autism: A prospective population-based follow-up study of 120 individuals diagnosed in childhood. Epilepsia, 46(6), 918–923.PubMedCrossRef Danielsson, S., Gillberg, I. C., Billstedt, E., Gillberg, C., & Olsson, I. (2005). Epilepsy in young adults with autism: A prospective population-based follow-up study of 120 individuals diagnosed in childhood. Epilepsia, 46(6), 918–923.PubMedCrossRef
go back to reference Depositario-Cabacar, D. F., & Zelleke, T. G. (2010). Treatment of epilepsy in children with developmental disabilities. Developmental Disabilities Research Reviews, 16(3), 239–247.PubMedCrossRef Depositario-Cabacar, D. F., & Zelleke, T. G. (2010). Treatment of epilepsy in children with developmental disabilities. Developmental Disabilities Research Reviews, 16(3), 239–247.PubMedCrossRef
go back to reference Doria-Rose, V. P., & Marcus, P. M. (2009). Death certificates provide an adequate source of cause of death information when evaluating lung cancer mortality: An example from the Mayo Lung Project. Lung Cancer, 63(2), 295–300.PubMedCrossRef Doria-Rose, V. P., & Marcus, P. M. (2009). Death certificates provide an adequate source of cause of death information when evaluating lung cancer mortality: An example from the Mayo Lung Project. Lung Cancer, 63(2), 295–300.PubMedCrossRef
go back to reference Farley, M. A., McMahon, W. M., Fombonne, E., Jenson, W. R., Miller, J., Gardner, M., et al. (2009). Twenty-year outcome for individuals with autism and average or near-average cognitive abilities. Autism, 2(2), 109–118.CrossRef Farley, M. A., McMahon, W. M., Fombonne, E., Jenson, W. R., Miller, J., Gardner, M., et al. (2009). Twenty-year outcome for individuals with autism and average or near-average cognitive abilities. Autism, 2(2), 109–118.CrossRef
go back to reference Gillberg, C., Billstedt, E., Sundh, V., & Gillberg, I. C. (2010). Mortality in autism: A prospective longitudinal community-based study. Journal of Autism and Developmental Disorders, 40(3), 352–357.PubMedCrossRef Gillberg, C., Billstedt, E., Sundh, V., & Gillberg, I. C. (2010). Mortality in autism: A prospective longitudinal community-based study. Journal of Autism and Developmental Disorders, 40(3), 352–357.PubMedCrossRef
go back to reference Gillberg, C., & Coleman, M. (1996). Autism and medical disorders: A review of the literature. Developmental Medicine and Child Neurology, 38, 191–202.PubMedCrossRef Gillberg, C., & Coleman, M. (1996). Autism and medical disorders: A review of the literature. Developmental Medicine and Child Neurology, 38, 191–202.PubMedCrossRef
go back to reference Isager, T., Mouridsen, S. E., & Rich, B. (1999). Mortality and causes of death in pervasive developmental disorders. Autism, 3, 7–16.CrossRef Isager, T., Mouridsen, S. E., & Rich, B. (1999). Mortality and causes of death in pervasive developmental disorders. Autism, 3, 7–16.CrossRef
go back to reference Kobayashi, R., Murata, T., & Yoshinaga, K. (1992). A follow-up study of 201 children with autism in Kyushu and Yamaguchi areas, Japan. Journal of Autism and Developmental Disorders, 22(3), 395–411.PubMedCrossRef Kobayashi, R., Murata, T., & Yoshinaga, K. (1992). A follow-up study of 201 children with autism in Kyushu and Yamaguchi areas, Japan. Journal of Autism and Developmental Disorders, 22(3), 395–411.PubMedCrossRef
go back to reference Larsson, H. J., Eaton, W. W., Madsen, K. M., Vestergaard, M., Olesen, A. V., Agerbo, E., et al. (2006). Risk factors for autism: Perinatal factors, parental psychiatric history, and socioeconomic status. American Journal of Epidemiology, 161(10), 916–925.CrossRef Larsson, H. J., Eaton, W. W., Madsen, K. M., Vestergaard, M., Olesen, A. V., Agerbo, E., et al. (2006). Risk factors for autism: Perinatal factors, parental psychiatric history, and socioeconomic status. American Journal of Epidemiology, 161(10), 916–925.CrossRef
go back to reference Miller, J. S., Bilder, D., Farley, M., Coon, H., Pinborough-Zimmerman, J., Jenson, W., et al. (2012). Autism spectrum disorder reclassified: A second look at the 1980’s Utah/UCLA Autism Epidemiologic Study. Journal of Autism and Developmental Disorders. doi:10.1007/s10803-012-1566-0. Miller, J. S., Bilder, D., Farley, M., Coon, H., Pinborough-Zimmerman, J., Jenson, W., et al. (2012). Autism spectrum disorder reclassified: A second look at the 1980’s Utah/UCLA Autism Epidemiologic Study. Journal of Autism and Developmental Disorders. doi:10.​1007/​s10803-012-1566-0.
go back to reference Mouridsen, S. E., & Brønnum-Hansen, H. (2008). Mortality and causes of death in autism spectrum disorders: An update. Autism, 12(4), 403–414.PubMedCrossRef Mouridsen, S. E., & Brønnum-Hansen, H. (2008). Mortality and causes of death in autism spectrum disorders: An update. Autism, 12(4), 403–414.PubMedCrossRef
go back to reference Pellock, J. (2004). Understanding co-morbidities affecting children with epilepsy. Neurology, 62(supplement 2), S17–S23.PubMedCrossRef Pellock, J. (2004). Understanding co-morbidities affecting children with epilepsy. Neurology, 62(supplement 2), S17–S23.PubMedCrossRef
go back to reference Pickett, J. A., Paculdo, D. R., Shavelle, R. M., & Strauss, D. J. (2006). 1998–2002 Update on “Causes of Death in Autism”. Journal of Autism and Developmental Disorders, 36, 287–288.PubMedCrossRef Pickett, J. A., Paculdo, D. R., Shavelle, R. M., & Strauss, D. J. (2006). 1998–2002 Update on “Causes of Death in Autism”. Journal of Autism and Developmental Disorders, 36, 287–288.PubMedCrossRef
go back to reference Pickett, J., Xiu, E., Tuchman, R., Dawson, G., & Lajonchere, C. (2011). Mortality in individuals with autism, with and without epilepsy. Journal of Child Neurology, 26(8), 932–939.PubMedCrossRef Pickett, J., Xiu, E., Tuchman, R., Dawson, G., & Lajonchere, C. (2011). Mortality in individuals with autism, with and without epilepsy. Journal of Child Neurology, 26(8), 932–939.PubMedCrossRef
go back to reference Pinborough-Zimmerman, J., Bakian, A., Fombonne, E., Bilder, D., Taylor, J., & McMahon, W. M. (2012). Changes in the administrative prevalence of autism spectrum disorders: Contribution of special education and health data from 2002–2008. Journal of Autism and Developmental Disorders, 42, 521–530. Pinborough-Zimmerman, J., Bakian, A., Fombonne, E., Bilder, D., Taylor, J., & McMahon, W. M. (2012). Changes in the administrative prevalence of autism spectrum disorders: Contribution of special education and health data from 2002–2008. Journal of Autism and Developmental Disorders, 42, 521–530.
go back to reference Rice, C. E., Baio, J., Van Naarden Braun, K., Doernberg, N., Meaney, F. J., Kirby, R. S., et al. (2007). A public health collaboration for the surveillance of autism spectrum disorders. Paediatric and Perinatal Epidemiology, 21(2), 179–190.PubMedCrossRef Rice, C. E., Baio, J., Van Naarden Braun, K., Doernberg, N., Meaney, F. J., Kirby, R. S., et al. (2007). A public health collaboration for the surveillance of autism spectrum disorders. Paediatric and Perinatal Epidemiology, 21(2), 179–190.PubMedCrossRef
go back to reference Ritvo, E. R., Freeman, B. J., Pingree, C., Mason-Brothers, A., Jorde, L., Jenson, W. R., et al. (1989). The UCLA-University of Utah epidemiologic survey of autism: Prevalence. American Journal of Psychiatry, 146(2), 194–199.PubMed Ritvo, E. R., Freeman, B. J., Pingree, C., Mason-Brothers, A., Jorde, L., Jenson, W. R., et al. (1989). The UCLA-University of Utah epidemiologic survey of autism: Prevalence. American Journal of Psychiatry, 146(2), 194–199.PubMed
go back to reference Ritvo, E. R., Mason-Brothers, A., Freeman, B. J., Pingree, C., Jenson, W. R., McMahon, W. M., et al. (1990). The UCLA-University of Utah epidemiologic survey of autism: The etiologic role of rare diseases. American Journal of Psychiatry, 147(12), 1614–1621.PubMed Ritvo, E. R., Mason-Brothers, A., Freeman, B. J., Pingree, C., Jenson, W. R., McMahon, W. M., et al. (1990). The UCLA-University of Utah epidemiologic survey of autism: The etiologic role of rare diseases. American Journal of Psychiatry, 147(12), 1614–1621.PubMed
go back to reference Shavelle, R. M., Strauss, D. J., & Pickett, J. (2001). Causes of death in autism. Journal of Autism and Developmental Disorders, 31, 569–576.PubMedCrossRef Shavelle, R. M., Strauss, D. J., & Pickett, J. (2001). Causes of death in autism. Journal of Autism and Developmental Disorders, 31, 569–576.PubMedCrossRef
go back to reference Symons, M. J., & Moore, D. T. (2002). Hazard rate ratio and prospective epidemiological studies. Journal of Clinical Epidemiology, 55(9), 893–899.PubMedCrossRef Symons, M. J., & Moore, D. T. (2002). Hazard rate ratio and prospective epidemiological studies. Journal of Clinical Epidemiology, 55(9), 893–899.PubMedCrossRef
go back to reference Van Naarden Braun, K., Pettygrove, S., Daniels, J., Miller, L., Nicholas, J., Baio, J., et al. (2007). Evaluation of a methodology for a collaborative multiple source surveillance network for autism spectrum disorders–Autism and Developmental Disabilities Monitoring Network, 14 sites, United States, 2002. Surveillance Summaries: Morbidity and Mortality Weekly Report, 56(1), 29–40. Van Naarden Braun, K., Pettygrove, S., Daniels, J., Miller, L., Nicholas, J., Baio, J., et al. (2007). Evaluation of a methodology for a collaborative multiple source surveillance network for autism spectrum disorders–Autism and Developmental Disabilities Monitoring Network, 14 sites, United States, 2002. Surveillance Summaries: Morbidity and Mortality Weekly Report, 56(1), 29–40.
go back to reference Yeargin-Allsopp, M., Rice, C., Karapurkar, T., Doernberg, N., Boyle, C., & Murphy, C. (2003). Prevalence of autism in a US metropolitan area. JAMA. Journal of the American Medical Association, 289(1), 49–55.PubMedCrossRef Yeargin-Allsopp, M., Rice, C., Karapurkar, T., Doernberg, N., Boyle, C., & Murphy, C. (2003). Prevalence of autism in a US metropolitan area. JAMA. Journal of the American Medical Association, 289(1), 49–55.PubMedCrossRef
Metagegevens
Titel
Excess Mortality and Causes of Death in Autism Spectrum Disorders: A Follow up of the 1980s Utah/UCLA Autism Epidemiologic Study
Auteurs
Deborah Bilder
Elizabeth L. Botts
Ken R. Smith
Richard Pimentel
Megan Farley
Joseph Viskochil
William M. McMahon
Heidi Block
Edward Ritvo
Riva-Ariella Ritvo
Hilary Coon
Publicatiedatum
01-05-2013
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 5/2013
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-012-1664-z

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