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Journal of Autism and Developmental Disorders

Gepubliceerd in:

01-08-2012 | Original Paper

Exploring the Relationship Between Autism Spectrum Disorder and Epilepsy Using Latent Class Cluster Analysis

Auteurs: Michael L. Cuccaro, Roberto F. Tuchman, Kara L. Hamilton, Harry H. Wright, Ruth K. Abramson, Jonathan L. Haines, John R. Gilbert, Margaret Pericak-Vance

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 8/2012

Abstract

Epilepsy co-occurs frequently in autism spectrum disorders (ASD). Understanding this co-occurrence requires a better understanding of the ASD-epilepsy phenotype (or phenotypes). To address this, we conducted latent class cluster analysis (LCCA) on an ASD dataset (N = 577) which included 64 individuals with epilepsy. We identified a 5-cluster solution with one cluster showing a high rate of epilepsy (29%), earlier age at first recognition, and high rates of repetitive object use and unusual sensory interests. We also conducted LCCA on an ASD-epilepsy subset from the overall dataset (N = 64) which yielded three clusters, the largest of which had impairments in language and motor development; the remaining clusters, while not as developmentally impaired were characterized by different levels of repetitive and sensory behaviors.

vorige artikel Behavioral and Physiological Responses to Child-Directed Speech of Children with Autism Spectrum Disorders or Typical Development

volgende artikel Self-Monitoring of Gaze in High Functioning Autism

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Titel: Exploring the Relationship Between Autism Spectrum Disorder and Epilepsy Using Latent Class Cluster Analysis
Auteurs: Michael L. Cuccaro
Roberto F. Tuchman
Kara L. Hamilton
Harry H. Wright
Ruth K. Abramson
Jonathan L. Haines
John R. Gilbert
Margaret Pericak-Vance
Publicatiedatum: 01-08-2012
Uitgeverij: Springer US
Gepubliceerd in: Journal of Autism and Developmental Disorders / Uitgave 8/2012
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI: https://doi.org/10.1007/s10803-011-1402-y

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