Top

Journal of Autism and Developmental Disorders

Gepubliceerd in:

01-11-2011 | Original Paper

Atypical Brain Responses to Reward Cues in Autism as Revealed by Event-Related Potentials

Auteurs: Gregor Kohls, Judith Peltzer, Martin Schulte-Rüther, Inge Kamp-Becker, Helmut Remschmidt, Beate Herpertz-Dahlmann, Kerstin Konrad

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 11/2011

Abstract

Social motivation deficit theories suggest that children with autism do not properly anticipate and appreciate the pleasure of social stimuli. In this study, we investigated event-related brain potentials evoked by cues that triggered social versus monetary reward anticipation in children with autism. Children with autism showed attenuated P3 activity in response to cues associated with a timely reaction to obtain a reward, irrespective of reward type. We attribute this atypical P3 activity in response to reward cues as reflective of diminished motivated attention to reward signals, a possible contributor to reduced social motivation in autism. Thus, our findings suggest a general reward processing deficit rather than a specific social reward dysfunction in autism.

vorige artikel Reliability of Eye Tracking and Pupillometry Measures in Individuals with Fragile X Syndrome

volgende artikel Judgments of Cause and Blame: Sensitivity to Intentionality in Asperger’s Syndrome

Achenbach, T. M. (1991). Manual for the child behavior checklist/4–18 and 1991 profile. Burlington, VT: University of Vermont, Department of Psychiatry.

Banaschewski, T., & Brandeis, D. (2007). Annotation: What electrical brain activity tells us about brain function that other techniques cannot tell us—A child psychiatric perspective. Journal of Child Psychology and Psychiatry, 48, 415–435.PubMedCrossRef

Blatter, K., & Schultz, W. (2006). Rewarding properties of visual stimuli. Experimental Brain Research, 168, 541–546.CrossRef

Botvinick, M. M., Huffstetler, S., & McGuire, J. T. (2009). Effort discounting in human nucleus accumbens. Cognitive, Affective, & Behavioral Neuroscience, 9, 16–27.CrossRef

Christ, S. E., Holt, D. D., White, D. A., & Green, L. (2007). Inhibitory control in children with autism spectrum disorder. Journal of Autism and Developmental Disorders, 37, 1155–1165.PubMedCrossRef

Constantino, J. N., & Gruber, C. P. (2002). Social responsiveness scale (SRS) manual. Los Angeles: Western Psychological Services.

Dawson, G. (2008). Early behavioral intervention, brain plasticity, and the prevention of autism spectrum disorder. Development and Psychopathology, 20, 775–803.PubMedCrossRef

Dawson, G., Finley, C., Phillips, S., Galpert, L., & Lewy, A. (1988). Reduced P3 amplitude of the event-related brain potential: Its relationship to language ability in autism. Journal of Autism and Developmental Disorders, 18, 493–504.PubMedCrossRef

Dawson, G., Meltzoff, A. N., Osterling, J., & Rinaldi, J. (1998). Neuropsychological correlates of early symptoms of autism. Child Development, 69, 1276–1285.PubMedCrossRef

Dawson, G., Osterling, J., Rinaldi, J., Carver, L., & McPartland, J. (2001). Recognition memory and stimulus-reward associations: Indirect support for the role of ventromedial prefrontal dysfunctions in autism. Journal of Autism and Developmental Disorders, 31, 337–341.PubMedCrossRef

Dawson, G., Webb, S. J., & McPartland, J. (2005). Understanding the nature of face processing impairment in autism: Insights from behavioral and electrophysiological studies. Developmental Neuropsychology, 27, 403–424.PubMedCrossRef

Döpfner, M., & Lehmkuhl, G. (1998). Diagnostik-System für psychische Störungen im Kindes- und Jugendalter nach ICD-10 und DSM-IV. Bern: Huber Verlag.

Freitag, G. (1970). An experimental study of the social responsiveness of children with autistic behaviors. Journal of Experimental Child Psychology, 9, 436–453.PubMedCrossRef

Garretson, H. B., Fein, D., & Waterhouse, L. (1990). Sustained attention in children with autism. Journal of Autism and Developmental Disorders, 20, 101–114.PubMedCrossRef

Geurts, H. M., Luman, M., & van Meel, C. S. (2008). What’s in a game: The effect of social motivation on interference control in boys with ADHD and autism spectrum disorders. Journal of Child Psychology and Psychiatry, 49, 848–857.PubMedCrossRef

Gleissner, U., von Ondarza, G., Freitag, H., & Karlmeier, A. (2003). Auswahl einer HAWIK-III-Kurzform für Kinder und Jugendliche mit Epilepsie. Zeitschrift für Neuropsychologie, 14, 3–11.CrossRef

Goldstein, R. Z., Cottone, L. A., Jia, Z., Maloney, T., Volkow, N. D., & Squires, N. K. (2006). The effect of graded monetary reward on cognitive event-related potentials and behavior in young healthy adults. International Journal of Psychophysiology, 62, 272–279.PubMedCrossRef

Groen, Y., Wijers, A. A., Mulder, L. J. M., Waggeveld, B., Minderaa, R. B., & Althaus, M. (2008). Error and feedback processing in children with ADHD and children with Autistic Spectrum Disorder: An EEG event-related potential study. Clinical Neurophysiology, 119, 2476–2493.PubMedCrossRef

Gunji, A., Inagaki, M., Inoue, Y., Takeshima, Y., & Kaga, M. (2009). Event-related potentials of self-face recognition in children with pervasive developmental disorders. Brain and Development, 31, 139–147.PubMedCrossRef

Hill, E. L. (2004). Evaluating the theory of executive dysfunction in autism. Developmental Review, 24, 189–233.CrossRef

Hughes, C. (1996). Brief report: Planning problems in autism at the level of motor control. Journal of Autism and Developmental Disorders, 26, 99–107.PubMedCrossRef

Jeste, S. S., & Nelson, C. A., I. I. I. (2009). Event related potentials in the understanding of autism spectrum disorders: An analytical review. Journal of Autism and Developmental Disorders, 39, 495–510.PubMedCrossRef

Kaufman, J., Birmaher, B., Brent, D., Rao, U., Flynn, C., Moreci, P., et al. (1997). Schedule for affective disorders and schizophrenia for school-age children-present and lifetime version (K-SADS-PL): Initial reliability and validity data. Journal of the American Academy for Child and Adolescent Psychiatry, 36, 980–988.CrossRef

Kohls, G., Peltzer, J., Herpertz-Dahlmann, B., & Konrad, K. (2009). Differential effects of social and non-social reward on response inhibition in children and adolescents. Developmental Science, 12, 614–625.PubMedCrossRef

Kylliäinen, A., Braeutigam, S., Hietanen, J. K., Swithenby, S. J., & Bailey, A. J. (2006). Face- and gaze-sensitive neural responses in children with autism: A magnetoencephalographic study. European Journal of Neuroscience, 24, 2679–2690.PubMedCrossRef

Lam, K. S. L., Aman, M. G., & Arnold, L. E. (2006). Neurochemical correlates of autistic disorder: A review of the literature. Research in Developmental Disabilities, 27, 254–289.PubMedCrossRef

Lord, G., Risi, S., Lambrecht, L., Cook, E. H., Jr., Leventhal, B. L., DiLavore, P. C., et al. (2000). The autism diagnostic observation schedule-generic: A standard measure of social and communication deficits associated with the spectrum of autism. Journal of Autism and Developmental Disorder, 30, 205–223.CrossRef

Lord, C., Rutter, M., & Le Couteur, A. (1994). Autism diagnostic interview-revised: A revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders. Journal of Autism and Developmental Disorder, 24, 659–685.CrossRef

Martchek, M., Thevarkunnel, S., Bauman, M., Blatt, G., & Kemper, T. (2006). Lack of evidence of neuropathology in the locus coeruleus in autism. Acta Neuropathologica, 111, 497–499.PubMedCrossRef

Matson, J. L., Benavidez, D. A., Stabinsky Compton, L., Paclawskyi, T., & Baglio, C. (1996). Behavioral treatment of autistic persons: A review of research from 1980 to the present. Research in Developmental Disabilities, 17, 433–465.PubMedCrossRef

Munson, J., Faja, S., Meltzoff, M., Abbott, R., & Dawson, G. (2008). Neurocognitive predictors of social and communicative developmental trajectories in preschoolers with autism spectrum disorders. Journal of the International Neuropsychological Society, 14, 956–966.PubMedCrossRef

Nieuwenhuis, S., Aston-Jones, G., & Cohen, J. D. (2005). Decision making, the P3, and the locus coeruleus-norepinephrine system. Psychological Bulletin, 131, 510–532.PubMedCrossRef

Oldfield, R. C. (1971). The assessment and analysis of handedness: The Edinburgh inventory. Neuropsychologia, 9, 97–113.PubMedCrossRef

Rademacher, L., Krach, S., Kohls, G., Irmak, A., Gründer, G., & Spreckelmeyer, K. N. (2010). Dissociation of neural networks for anticipation and consumption of monetary and social rewards. Neuroimage, 49, 3276–3285.PubMedCrossRef

Rinehart, N. J., Bellgrove, M. A., Tonge, B. J., Brereton, A. V., Howells-Rankin, D., & Bradshaw, J. L. (2006). An examination of movement kinematics in young people with high-functioning autism and Asperger’s disorder: Further evidence for a motor planning deficit. Journal of Autism and Developmental Disorder, 36, 757–767.CrossRef

Rutter, M., Bailey, A., & Lord, C. (2003). Social Communication Questionnaire. Manual for the SCQ. Los Angeles, CA: Western Psychological Services.

Schmitz, N., Rubia, K., van Amelsvoort, T., Daly, E., Smith, A., & Murphy, D. G. M. (2008). Neural correlates of reward in autism. The British Journal of Psychiatry, 192, 19–24.PubMedCrossRef

Schultz, R. T. (2005). Developmental deficits in social perception in autism: The role of the amygdala and fusiform face area. International Journal of Developmental Neuroscience, 23, 125–141.PubMedCrossRef

Scott-Van Zeeland, A. A., Dapretto, M., Ghahremani, D. G., Poldrack, R. A., & Bookheimer, S. (2010). Reward processing in autism. Autism Research, 3, 53–67.PubMed

Wu, Y., & Zhou, X. (2009). The P300 and reward valence, magnitude, and expectancy in outcome evaluation. Brain Research, 1286, 114–122.PubMedCrossRef

Titel: Atypical Brain Responses to Reward Cues in Autism as Revealed by Event-Related Potentials
Auteurs: Gregor Kohls
Judith Peltzer
Martin Schulte-Rüther
Inge Kamp-Becker
Helmut Remschmidt
Beate Herpertz-Dahlmann
Kerstin Konrad
Publicatiedatum: 01-11-2011
Uitgeverij: Springer US
Gepubliceerd in: Journal of Autism and Developmental Disorders / Uitgave 11/2011
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI: https://doi.org/10.1007/s10803-011-1177-1

Bohn Stafleu van Loghum

Deel dit onderdeel of sectie (kopieer de link)

Abstract

Log in om toegang te krijgen

Andere artikelen Uitgave 11/2011

A Pilot Study Examining Activity Participation, Sensory Responsiveness, and Competence in Children with High Functioning Autism Spectrum Disorder

Response to Hobson’s Letter: Congenital Blindness and Autism

Investigating Multitasking in High-Functioning Adolescents with Autism Spectrum Disorders Using the Virtual Errands Task

Diminished Sensitivity to Sad Facial Expressions in High Functioning Autism Spectrum Disorders is Associated with Symptomatology and Adaptive Functioning

Performance of Children with Autism on the Embedded Figures Test: A Closer Look at a Popular Task

Reliability of Eye Tracking and Pupillometry Measures in Individuals with Fragile X Syndrome