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Gepubliceerd in: Journal of Autism and Developmental Disorders 5/2008

01-05-2008 | Brief Report

Brief Report: An Autistic Spectrum Subtype Revealed Through Familial Psychopathology Coupled with Cognition in ASD

Auteurs: Renée Lajiness-O’Neill, Philip Menard

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 5/2008

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Abstract

This study identified a possible autistic spectrum subtype expressed through family psychopathology coupled with autistic probands’ cognitive functioning (i.e., an endophenotypic profile). Participants included 24 children with Autism Spectrum Disorder (ASD) and 49 children with Learning Disorder (LD). There were significantly higher rates of Mood and Anxiety Disorder in first degree maternal relatives and of LD and Attention-Deficit Hyperactivity Disorder in first degree paternal relatives of ASD probands. Significantly higher visuospatial functioning was noted in all ASD probands for which there were higher rates of Mood Disorder on the maternal side suggesting a possible marker for an ASD subtype and indicating that maternal psychopathology may have a neuroprotective effect on visuospatial functioning.
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Metagegevens
Titel
Brief Report: An Autistic Spectrum Subtype Revealed Through Familial Psychopathology Coupled with Cognition in ASD
Auteurs
Renée Lajiness-O’Neill
Philip Menard
Publicatiedatum
01-05-2008
Uitgeverij
Springer US
Gepubliceerd in
Journal of Autism and Developmental Disorders / Uitgave 5/2008
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI
https://doi.org/10.1007/s10803-007-0464-3

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