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Journal of Autism and Developmental Disorders

Gepubliceerd in:

01-03-2007 | Original Paper

Quantitative Assessment of Autism Symptom-related Traits in Probands and Parents: Broader Phenotype Autism Symptom Scale

Auteurs: Geraldine Dawson, Annette Estes, Jeffrey Munson, Gerard Schellenberg, Raphael Bernier, Robert Abbott

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 3/2007

Abstract

Autism susceptibility genes likely have effects on continuously distributed autism-related traits, yet few measures of such traits exist. The Broader Phenotype Autism Symptom Scale (BPASS), developed for use with affected children and family members, measures social motivation, social expressiveness, conversational skills, and flexibility. Based on 201 multiplex families, psychometric data on the BPASS are reported. Adequate inter-rater reliability and internal consistency were found. Parents had lower BPASS scores than affected children, after controlling for IQ. Parents and affected children showed overlapping distributions suggesting the BPASS captured variability in traits across groups. BPASS scores were not correlated with ethnicity or parent education; however, some domains were correlated with IQ. The BPASS holds promise as a quantitative phenotypic assessment for genetic studies.

vorige artikel Orientation and Affective Expression Effects on Face Recognition in Williams Syndrome and Autism

volgende artikel Neuropsychological Functioning of Siblings of Children with Autism, Siblings of Children with Developmental language Delay, and Siblings of Children with Mental Retardation of Unknown Genetic Etiology

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Titel: Quantitative Assessment of Autism Symptom-related Traits in Probands and Parents: Broader Phenotype Autism Symptom Scale
Auteurs: Geraldine Dawson
Annette Estes
Jeffrey Munson
Gerard Schellenberg
Raphael Bernier
Robert Abbott
Publicatiedatum: 01-03-2007
Uitgeverij: Kluwer Academic Publishers-Plenum Publishers
Gepubliceerd in: Journal of Autism and Developmental Disorders / Uitgave 3/2007
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI: https://doi.org/10.1007/s10803-006-0182-2

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