Top

Journal of Autism and Developmental Disorders

Gepubliceerd in:

01-02-2007 | Original Paper

Cognitive and Verbal Abilities of 24- to 36-month-old Siblings of Children with Autism

Auteurs: Nurit Yirmiya, Ifat Gamliel, Michal Shaked, Marian Sigman

Gepubliceerd in: Journal of Autism and Developmental Disorders | Uitgave 2/2007

Abstract

The cognitive and language skills of 30 siblings of children with autism (SIBS-A) and 30 siblings of typically developing children (SIBS-TD) were compared. Non-significant group differences emerged for cognition at both ages. At 24 months, significantly more SIBS-A demonstrated language scores one or two standard deviations below the mean compared to SIBS-TD. At 36 months, the groups differed significantly in receptive language, and more SIBS-A displayed receptive and expressive difficulties compared to SIBS-TD. Six SIBS-A (including one diagnosed with autism) revealed language scores more than two standard deviations below the mean at both ages, a pattern not seen in the SIBS-TD. Results are discussed in reference to language difficulties in autism spectrum disorders and the genetic liability for autism.

vorige artikel MMR-Vaccine and Regression in Autism Spectrum Disorders: Negative Results Presented from Japan

volgende artikel Involvement or Isolation? The Social Networks of Children with Autism in Regular Classrooms

Alarcon, M., Cantor, R. M., Liu, J., Gilliam, T. C., & Geschwind, D. H. (2002). The autism genetic resource exchange consortium. Evidence for a language quantitative trait locus on chromosome 7q in multiplex families. American Journal of Human Genetics, 70, 60–71.PubMedCrossRef

American Psychiatric Association (1994). Diagnostic and statistical manual of mental disorders (4th edn). Washington, DC: Author.

Ashley-Koch, A., Wolpert, C. M., Menold, M. M., Zaeem, L., Basu, S., Donnelly, S. L., Ravan, S. A., Powell, C. M., Qumsiyeh, M. B., Aylsworth, A. S., Vance, J. M., Gilbert, J. R., Wright, H. H., Abramson, R. K., Delong, G. R., Cuccaru, M. L., & Pericak-Vance, M. A. J. (1999). Genetic studies of autistic disorder. Genomics, 61, 227–236.PubMedCrossRef

August, G. J., Stewart, M. A., & Tsai, L. (1981). The incidence of cognitive disabilities in the siblings of autistic children. British Journal of Psychiatry, 138, 416–422.PubMedCrossRef

Baron-Cohen, S., Allen, J., & Gillberg, C. (1992). Can autism be detected at 18 months? The needle, the haystack and the CHAT. British Journal of Psychiatry, 161, 839–843.PubMedCrossRef

Barrett, S., Beck, J., Bernier, R., Bisson, E., Braun, T., Casavant, T., Childress, D., Folstein, S., Garcia, M., Gardiner, M., Gilman, S., Haines, J., Hopkins, K., Landa, R., Meyer, N., Mullane, J., Nishimura, D., Palmer, P., Piven, J., Purdy, J., Santangelo, J., Searby, C., Sheffield, V., Singleton, J., Slager, S., Struchen, T., Svenson, S., Vieland, V., Wang, K., & Winklosky, B. (1999). An autosomal genomic screen for autism. American Journal of Medical Genetics, 88, 609–615.PubMedCrossRef

Bartlett, C. W., Flax, J. F., Logue, M. W., Smith, B. J., Vieland, V. J., Tallal, P. et al., (2004). Examination of potential overlap in autism and language loci on chromosomes 2, 7, and 13 in two independent samples ascertained for specific language impairment. Human Heredity, 57, 10–20.PubMedCrossRef

Bates, J. E., Freeland, C. A., & Lounsbury, M. L. (1979). Measurement of infant difficultness. Child Development, 50, 794–803.PubMedCrossRef

Bayley, N. (1993). Bayley scales of infant development (2nd ed.). San Antonio, TX: Psychological Corporation.

Berument, S. K., Rutter, M., Lord, C., Pickles, A., & Bailey, A. (1999). Autism screening questionnaire: Diagnostic validity. British Journal of Psychiatry, 175, 444–451.PubMed

Bishop, D. V. M. (2003). Genetic and environmental risks for specific impairment in children. International Journal of Pediatric Otorhinolaryngology, 6751, S143–S157.CrossRef

Bishop, D. V. M., Price, T. S., Dale, P. S., & Plomin, R. (2003). Outcomes of early language delay: II. Etiology of transient and persistent language difficulties. Journal of Speech Language and Hearing Research, 46, 561–575.CrossRef

Bloom, L. (1993). The transition from infancy to language: Acquiring the power of expression. Cambridge, England: Cambridge University Press.

Bloom, L. (1998). Language acquisition in its developmental context. In W. Damon (Ed.) Handbook of child psychology, Vol. 2. Cognition, preparation and language (5th ed., pp. 309–370). New York: Wiley.

Bolton, P., Macdonald, H., Pickles, A. Rios, P., & Goode, S. (1994). A case–control family history study of autism. Journal of Child Psychology and Psychiatry, 35, 877–900.PubMedCrossRef

Charman, T., Baron-Cohen, S., Swettenham, J., Baird, G., Drew, A., & Cox, A. (2003a). Predicting language outcome in infants with autism and pervasive developmental disorders. The International Journal of Language and Communication Disorders, 38, 265–285.CrossRef

Charman, T., Drew, A., Baird, C., & Baird, G. (2003b). Measuring early language development in preschool children with autism spectrum disorders using the McArthur Communicative Development Inventory (Infant Form). Journal of Child Language, 30, 213–236.CrossRef

Coonrod, E., & Stone, W. L. (2004). Early concerns of parents of children with autistic and nonautistic disorders. Infants and Young Children, 17, 258–268.CrossRef

Dawson, G., Webb, S., Schellenberg, G. D., Dager, S., Friedman, S., Aylward, E., & Richards, T. (2002). Defining the broader phenotype of autism: Genetic, brain and behavioral perspectives. Development and Psychopathology, 14, 581–611.PubMedCrossRef

De Giacomo, A., & Fombonne, E. (1998). Parental recognition of developmental abnormalities in autism. European Child and Adolescent Psychiatry, 7, 131–136.PubMedCrossRef

Folstein, S., & Rutter, M. (1977). Infantile autism: A genetic study of 21 twin pairs. Journal of Child Psychology and Psychiatry, 18, 297–321.PubMedCrossRef

Fombonne, E., Bolton, P., Prior, J., Jordan, H., & Rutter, M. (1997). A family study of autism: Cognitive patterns and levels in parents and siblings. Journal of Child Psychology and Psychiatry, 38, 667–684.PubMedCrossRef

Gillberg, C., Gillberg, I. C., & Stefenburg, S. (1992). Siblings and parents of children with autism: A controlled population-based study. Developmental Medicine and Child Neurology, 34, 389–398.PubMedCrossRef

Goldfield, B., & Reznick, J. S. (1990). Early lexical acquisition: Rate, content, and the vocabulary spurt. Journal of Child Language, 17, 171–183.PubMedCrossRef

International Molecular Genetic Study Group of Autism Consortium (IMGSAC) (2001). A genomewide screen for autism: Strong evidence for linkage to chromosomes 2q, 7q and 16p. American Journal of Human Genetics, 69, 570–581.CrossRef

Kaufman, A. S., & Kaufman, N. L. (1983). Kaufman assessment battery for children (K-ABC). Circle Pines, MN: AGS.

Leboyer M., Plumet M. H., Goldblum M. C., Perez-Diaz F., & Marchaland, C. (1995). Verbal versus visuospatial abilities in relatives of autistic females. Developmental Neuropsychology, 11, 139–155.CrossRef

LeCouteur A., Bailey A., Goode S., Pickles A., Robertson S., Gottesman I., & Rutter, M. (1996). A broader phenotype of autism: The clinical spectrum in twins. Journal of Child Psychology and Psychiatry, 37, 785–801.CrossRef

Lord C. (1995). Follow up of two-year-olds referred for possible Autism. Journal of Child Psychology and Psychiatry and Allied Disciplines, 36, 1365–1382.

Lord C., Rutter M., & LeCouteur, A. (1994). Autism diagnostic interview-revised: A revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders. Journal of Autism and Developmental Disorders, 24, 659–685.PubMedCrossRef

Narayan S., Moyes B., & Wolff, S. (1990). Family characteristics of autistic children: A further report. Journal of Autism and Developmental Disorders, 20, 523–535.PubMedCrossRef

Ozonoff S., Rogers S. J., Farnham J. M., & Pennington, B. F. (1993). Can standard measures identify subclinical markers of autism?. Journal of Autism and Developmental Disorders, 23, 429–441.PubMedCrossRef

Pilowsky T., Yirmiya N., Shalev R., & Gross-Tsur, V. (2003). Language abilities of siblings of children with autism. Journal of Child Psychology and Psychiatry, 44, 914–925.PubMedCrossRef

Plumet M. H., Goldblum M. C., & Leboyer, M. (1995). Verbal skills in relatives of autistic females. Cortex, 31, 723–733.PubMed

Rapin I., & Dunn, M. (2003). Update on the language disorders of individuals on the autistic spectrum. Brain and Development, 25, 166–172.PubMedCrossRef

Reynell, J. K., & Grubber, C. P. (1990). Reynell developmental language scale. Los Angeles: Western Psychological Association.

Rodrigue, J. R., Geffken, G. R., & Morgan, S. B. (1993). Perceived competence and behavioral adjustment of siblings of children with autism. Journal of Autism and Developmental Disorders, 23, 665–674.PubMedCrossRef

Silverman, J. M., Smith, C. J., Schmeidler, J., Hollander, E., Lawlor, B. A., Fitzgerald, M., Buxbaum, J. D., Delaney, K., & Galvin, P. (2002). System domains in autism and related conditions: Evidence for familiality. American Journal of Medical Genetics (Neuropsychiatric genetics), 114, 64–73.CrossRef

Smalley, S. L., & Asarnow, R. F. (1990). Brief report: Cognitive subclinical markers in autism. Journal of Autism and Developmental Disorders, 20, 271–278.PubMedCrossRef

Sparrow, S. S., Balla, D. A., & Cicchetti, D. V. (1985). Vineland adaptive behavior scales. Circle Pines, MN: American Guidance Services.

Spinath, F. M., Price, T. S., Dale, P. S., & Plomin, R. (2004). The genetic and environmental origins of language disability and ability. Child Development, 75, 445–454.PubMedCrossRef

Szatmari, P., Jones, M. B., Tuff, L., Bartolucci, G., Fisman, S., & Mahoney, W. (1993). Lack of cognitive impairment in first-degree relatives of children with pervasive developmental disorders. Journal of the American Academy of Child and Adolescent Psychiatry, 32, 1264–1273.PubMedCrossRef

Tager-Flusberg, H., & Cooper, J. (1999). Present and future possibilities for defining a phenotype for specific language impairment. Journal of Speech, Language and Hearing Research, 42, 1001–1004.

Tomblin, J. B., Hafeman, L. L., & O’Brien, M. (2003). Autism and autism risk in siblings of children with specific language impairment. International Journal of Language and Communication Disorders, 38(3), 235–250.PubMedCrossRef

Wechsler, D. (1991). Wechsler intelligence scale for children. (3rd ed.). San Antonio, TX: Psychological Corporation (WISC-III).

Wiig, E. H., Secord, W., & Semel, E. (1992). CELF-preschool: Clinical evaluation of language fundamentals—preschool version. San Antonio, TX: Psychological Corporation.

Yirmiya, N., Gamliel, I., Pilowsky, T., Baron-Cohen, S., Feldman, R., & Sigman, M. (2006). The development of siblings of children with autism at 4 and 14 months: Social engagement, communication, and cognition. Journal of Child Psychology and Psychiatry, 47, 511–523.PubMedCrossRef

Yirmiya, N., Shaked, M., & Erel, O. (2001). Comparison of siblings of individuals with autism and siblings of individuals with other diagnoses: An empirical summary. In: E. Schopler, N. Yirmiya, C. Shulman, & L. M. Marcus (Eds.), The research basis for autism intervention (pp. 59–73). New York: Kluwer Academic/Plenum.

Titel: Cognitive and Verbal Abilities of 24- to 36-month-old Siblings of Children with Autism
Auteurs: Nurit Yirmiya
Ifat Gamliel
Michal Shaked
Marian Sigman
Publicatiedatum: 01-02-2007
Uitgeverij: Kluwer Academic Publishers-Plenum Publishers
Gepubliceerd in: Journal of Autism and Developmental Disorders / Uitgave 2/2007
Print ISSN: 0162-3257
Elektronisch ISSN: 1573-3432
DOI: https://doi.org/10.1007/s10803-006-0163-5

Bohn Stafleu van Loghum

Deel dit onderdeel of sectie (kopieer de link)

Abstract

Log in om toegang te krijgen

Andere artikelen Uitgave 2/2007

Response Times of Children and Adolescents with Asperger Syndrome on an ‘Advanced’ Test of Theory of Mind

Announcements

Initial Characteristics of Psychological Development and Evolution of the Young Autistic Child

Risperidone Improves Behavioral Symptoms in Children with Autism in a Randomized, Double-Blind, Placebo-Controlled Trial

Sexual Behavior in High-Functioning Male Adolescents and Young Adults with Autism Spectrum Disorder

MMR-Vaccine and Regression in Autism Spectrum Disorders: Negative Results Presented from Japan