Abstract
Although Attention Deficit/Hyperactivity Disorder (ADHD) has increasingly been studied in preschool-aged children, relatively few studies have provided a comprehensive evaluation of the factor structure and patterns of developmental changes in parent-reported ADHD symptomatology across the early childhood period. This study used confirmatory factor analyses to test for longitudinal measurement invariance of ADHD symptoms and semi-parametric finite mixture models to identify prototypic patterns of developmental changes in ADHD symptomatology from 3 to 5 years of age. Participants were 1155 children and their parents who participated in a prospective longitudinal study involving a representative sample of children who resided in six non-metropolitan counties in the United States. Results indicated that (1) ADHD symptomatology was best represented by a single latent factor that exhibited partial measurement invariance from 3 to 5 years of age, (2) 8.5 % of children exhibited sustained high levels of ADHD symptoms from age 3–5 years, and (3) a variety of risk factors differentiated children with sustained high from those with sustained low levels of ADHD, relatively few (most notably caregiver education) were able to differentiate children with sustained high levels of ADHD symptoms from all other groups. Children who exhibit persistent ADHD symptomatology across the early childhood period may define a clinically important group for etiologic research and/or early intervention efforts.
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References
American Psychiatric Association. (1980). Diagnostic and statistical manual of mental disorders third edition (DSM-III). Washington: American Psychiatric Association.
American Psychiatric Association. (1987). Diagnostic and statistical manual of mental disorders third edition revised (DSM-IIIR). Washington: American Psychiatric Association.
American Psychiatric Association. (2000). Diagnostic and statistical manual of mental disorders fourth edition-text revision (DSM-IV-TR). Washington: American Psychiatric Association.
Bauer, D. J. (2007). Observations on the use of growth mixture models in psychological research. Multivariate Behavioral Research, 42, 757–786.
Bauer, D. J., & Curran, P. J. (2003). Distributional assumptions of growth mixture models: Implications for over-extraction of latent trajectory classes. Psychological Methods, 8, 338–363.
Bauermeister, J. J., Canino, G., Polanczyk, G., & Rohde, L. A. (2010). ADHD across cultures: Is there evidence for a bidimensional organization of symptoms? Journal of Clinical Child and Adolescent Psychology, 39, 362–372.
Becker, K., El-Faddagh, M., Schmidt, M. H., Esser, G., & Laucht, M. (2008). Interaction of dopamine transporter genotype with prenatal smoke exposure on ADHD symptoms. Journal of Pediatrics, 152, 263–269.
Biederman, J., Milberger, S., Faraone, S. V., Kiely, K., Guite, J., Mick, E., et al. (1995). Family-environment risk-factors for Attention-Deficit Hyperactivity Disorder - A test of Rutters indicators of adversity. Archives of General Psychiatry, 52, 464–470.
Biederman, J., Faraone, S.-V., & Monuteaux, M.-C. (2002). Differential effect of environmental adversity by gender: Rutter’s Index of Adversity in a group of boys and girls with and without ADHD. American Journal of Psychiatry. Sep, 159, 1556–1562.
Biederman, J., Faraone, S. V., Monuteaux, M. C., & Grossbard, J. R. (2004). How informative are parent reports of attention-deficit/hyperactivity disorder symptoms for assessing outcome in clinical trials of long-acting treatments? A pooled analysis of parents’ and teachers’ reports. Pediatrics, 113, 1667–1671.
Browne, M. W., & Cudeck, R. (1993). Alternative ways of assessing model fit. In K. A. Bollen & J. S. Long (Eds.), Testing structural equation models (pp. 137–162). Newbury Park: Sage Publications, Inc.
Burden, M. J., Jacobson, J. L., Westerlund, A., Lundahl, L. H., Morrison, A., Dodge, N., et al. (2010). An event-related potential study of response inhibition in ADHD with and without prenatal alcohol exposure. Alcoholism, Clinical and Experimental Research, 34, 617–627.
Byrne, B. M., Shavelson, R. J., & Muthén, B. (1989). Testing for the equivalence of factor covariance and mean structures: the issue of partial measurement invariance. Psychological Bulletin, 105, 456–466.
Byrne, J. M., DeWolfe, N. A., & Bawden, H. N. (1998). Asessment of Attention-Deficit Hyperactivity Disorder in preschoolers. Child Neuropsychology, 4, 49–66.
Campbell, S. B., Breaux, A. M., Ewing, L. J., Szumowski, E. K., & Pierce, E. W. (1986). Parent-identified problem preschoolers - mother-child interaction during play at intake and 1-year follow-up. Journal of Abnormal Child Psychology, 14, 425–440.
Chacko, A., Wakschlag, L., Hill, C., Danis, B., & Espy, K. A. (2009). Viewing preschool disruptive behavior disorders and Attention-Deficit/Hyperactivity Disorder through a developmental lens: What we know and what we need to know. Child and Adolescent Psychiatric Clinics of North America, 18, 627–643.
Cheung, G. W., & Rensvold, R. B. (2002). Evaluating goodness-of-fit indexes for testing measurement invariance. Structural Equation Modeling, 9, 233–255.
Connor, D. (2002). Preschool attention deficit hyperactivity disorder: A review of prevalence, diagnosis, neurobiology, and stimulant treatment. Journal of Developmental and Behavioral Pediatrics, 23, S1–S9.
Das Banerjee, T., Middleton, F., & Faraone, S. V. (2007). Environmental risk factors for attention-deficit hyperactivity disorder. Acta Paediatrica, 96, 1269–1274.
Derogatis, L. (2000). Brief symptom inventory 18. Minneapolis: NCS Pearson, Inc.
Derogatis, L. R., & Melisaratos, N. (1983). The brief symptom inventory: An introductory report. Psychological Medicine, 13, 595–605.
Dill, B. T. (2001). Rediscovering rural America. In J. R. Blau (Ed.), Blackwell companions to sociology (pp. 196–210). Malden: Blackwell Publishing.
Dopfner, M., Rothenberger, A., & Sonuga-Barke, E. (2004). Areas for future investment in the field of ADHD: Preschoolers and clinical networks. European Child & Adolescent Psychiatry, 13, I130–I135.
DuPaul, G. J., Anastopoulos, A. D., Power, T. J., Reid, R., Ikeda, M. J., & McGoey, K. E. (1998). Parent ratings of attention-deficit/hyperactivity disorder symptoms: factor structure and normative data. Journal of Psychopathology and Behavioral Assessment, 20, 83–102.
Durston, S., Thomas, K. M., Yang, Y. H., Ulug, A. M., Zimmerman, R. D., & Casey, B. J. (2002). A neural basis for the development of inhibitory control. Developmental Science, 5, F9–F16.
Durston, S., Davidson, M. C., Tottenham, N., Galvan, A., Spicer, J., Fossella, J. A., et al. (2006). A shift from diffuse to focal cortical activity with development. Developmental Science, 9, 1–8.
Egger, H. L., & Angold, A. (2006). Common emotional and behavioral disorders in preschool children: Presentation, nosology, and epidemiology. Journal of Child Psychology and Psychiatry, 47, 313–337.
Egger, H. L., Kondo, D., & Angold, A. (2006). The epidemiology and diagnostic issues in preschool attention-deficit/hyperactivity disorder - A review. Infants and Young Children, 19, 109–122.
Galera, C., Cote, S. M., Bouvard, M. P., Pingault, J. B., Melchior, M., Michel, G., et al. (2011). Early risk factors for hyperactivity-impulsivity and inattention trajectories from age 17 months to 8 years. Archives of General Psychiatry, 68, 1267–1275.
Gimpel, G., & Kuhn, B. (2000). Maternal report of attention deficit hyperactivity disorder symptoms in preschool children. Child: Care, Health and Development, 26, 163–179.
Hardy, K. K., Kollins, S. H., Murray, D. W., Riddle, M. A., Greenhill, L., Cunningham, C., et al. (2007). Factor structure of parent- and teacher-rated attention-deficit/hyperactivity disorder symptoms in the Preschoolers with Attention-Deficit/Hyperactivity Disorder Treatment Study (PATS). Journal of Child and Adolescent Psychopharmacology, 17, 621–633.
Harvey, E. A., Youngwirth, S. D., Thakar, D. A., & Errazuriz, P. A. (2009). Predicting attention deficit/hyperactivity disorder and oppositional defiant disorder from preschool diagnostic assessments. Journal of Consulting and Clinical Psychology, 77, 349–354.
Hu, L-t, & Bentler, P. M. (1999). Cutoff criteria for fit indexes in covariance structure analysis: conventional versus new alternatives. Structural Equation Modeling, 6, 1–55.
Jester, J. M., Nigg, J. T., Adams, K., Fitzgerald, H. E., Puttler, L. I., Wong, M. M., et al. (2005). Inattention/hyperactivity and aggression from early childhood to adolescence: Heterogeneity of trajectories and differential influence of family environment characteristics. Development and Psychopathology, 17, 99–125.
Jones, B. L., Nagin, D. S., & Roeder, K. (2001). A SAS procedure based on mixture models for estimating developmental trajectories. Sociological Research and Methods, 29, 374–393.
Kahn, R. S., Khoury, J., Nichols, W. C., & Lanphear, B. P. (2003). Role of dopamine transporter genotype and maternal prenatal smoking in childhood hyperactive-impulsive, inattentive, and oppositional behaviors. Journal of Pediatrics, 143, 104–110.
Lavigne, J. V., Arend, R., Rosenbaum, D., Binns, H. J., Christoffel, K. K., & Gibbons, R. D. (1998a). Psychiatric disorders with onset in the preschool years: I. Stability of diagnoses. Journal of the American Academy of Child and Adolescent Psychiatry, 37, 1246–1254.
Lavigne, J. V., Arend, R., Rosenbaum, D., Binns, H. J., Christoffel, K. K., & Gibbons, R. D. (1998b). Psychiatric disorders with onset in the preschool years: II. Correlates and predictors of stable case status. Journal of the American Academy of Child and Adolescent Psychiatry, 37, 1255–1261.
Leblanc, N., Boivin, M., Dionne, G., Brendgen, M., Vitaro, F., Tremblay, R. E., et al. (2008). The development of hyperactive-impulsive behaviors during the preschool years: The predictive validity of parental assessments. Journal of Abnormal Child Psychology, 36(7), 977–987.
Lee, S. S., Lahey, B. B., Owens, E. B., & Hinshaw, S. P. (2008). Few preschool boys and girls with ADHD are well-adjusted during adolescence. Journal of Abnormal Child Psychology, 36, 373–383.
McGoey, K., Eckert, T., & DuPaul, G. (2002). Early intervention for preschool-age children with ADHD: A literature review. Journal of Emotional and Behavioral Disorders, 10, 14–28.
Meredith, W. (1993). Measurement invariance, factor analysis and factorial invariance. Psychometrica, 58, 525–543.
Meredith, W., & Horn, J. (2001). The role of factorial invariance in modeling growth and change. In L. M. Collins & A. G. Sayer (Eds.), New methods for the analysis of change (1st ed., pp. 203–240). Washington: American Psychological Association.
Mick, E., Biederman, J., Faraone, S. V., Sayer, J., & Kleinman, S. (2002). Case–control study of attention-deficit hyperactivity disorder and maternal smoking, alcohol use and drug use during pregnancy. Journal of the American Academy of Child and Adolescent Psychiatry, 41(4), 378–385.
Muthén, L. K., & Muthén, B. O. (1998–2010). Mplus users guide. 6 Edition. Los Angeles, CA: Muthén & Muthén.
Nagin, D. S. (1999). Analyzing developmental trajectories: A semi-parametric, group-based approach. Psychological Methods, 4, 139–157.
Neuman, R. J., Lobos, E., Reich, W., Henderson, C. A., Sun, L. W., & Todd, R. D. (2007). Prenatal smoking exposure and dopaminergic genotypes interact to cause a severe ADHD subtype. Biological Psychiatry, 61, 1320–1328.
Palfrey, J. S., Levine, M. D., Walker, D. K., & Sullivan, M. (1985). The emergence of attention deficits in early childhood: a prospective study. Journal of Developmental and Behavioral Pediatrics, 6, 339–348.
Pelham, W. E., Gnagy, E. M., Greenslade, K. E., & Milich, R. (1992). Teacher ratings of DSM-III–R symptoms for the disruptive behavior disorders. Journal of the American Academy of Child and Adolescent Psychiatry, 31, 210–218.
Posner, K., Melvin, G. A., Murray, D. W., Gugga, S. S., Fisher, P., Skrobala, A., et al. (2007). Clinical presentation of Attention-Deficit/Hyperactivity Disorder in preschool children: The preschoolers with Attention-Deficit/Hyperactivity treatment study (PATS). Journal of Child and Adolescent Psychopharmacology, 17, 547–562.
Power, T. J., Andrews, T. J., Eiraldi, R. B., Doherty, B. J., Ikeda, M. J., DuPaul, G. J., et al. (1998). Evaluating Attention Deficit/Hyperactivity Disorder using multiple informants: The incremental utility of combining teacher with parent reports. Psychological Assessment, 10(3), 250–260.
Reich, W., Todd, R. D., Joyner, C. A., Neuman, R. J., & Heath, A. C. (2003). Reliability and stability of mothers’ reports about their pregnancies with twins. Twin Research, 6, 85–88.
Romano, E., Tremblay, R. E., Farhat, A., & Cote, S. (2006). Development and prediction of hyperactive symptoms from 2 to 7 years in a population-based sample. Pediatrics, 117, 2101–2110.
Satorra, A., & Bentler, P. M. (2001). A scaled difference chi-square test statistic for moment structure analysis. Psychometrika, 66, 507–514.
Shaw, D. S., Lacourse, E., & Nagin, D. S. (2005). Developmental trajectories of conduct problems and hyperactivity from ages 2 to 10. Journal of Child Psychology and Psychiatry, 46, 931–942.
Sonuga-Barke, E. J., Auerbach, J., Campbell, S. B., Daley, D., & Thompson, M. (2005). Varieties of preschool hyperactivity: multiple pathways from risk to disorder. Developmental Science, 8, 141–150.
Sonuga-Barke, E. J. S., Thompson, M., Abikoff, H., Klein, R., & Brotman, L. M. (2006). Nonpharmacological interventions for preschoolers with ADHD - The case for specialized parent training. Infants and Young Children, 19, 142–153.
Sprafkin, J., Gadow, K. D., & Nolan, E. E. (2001). The utility of a DSM-IV-referenced screening instrument for attention-deficit/hyperactivity disorder. Journal of Emotional and Behavioral Disorders, 9, 182–191.
St Sauver, J. L., Barbaresi, W. J., Katusic, S. K., Colligan, R. C., Weaver, A. L., & Jacobsen, S. J. (2004). Early life risk factors for attention-deficit/hyperactivity disorder: a population-based cohort study. Mayo Clinic Proceedings, 79, 1124–1131.
Tandon, M., Si, X. M., & Luby, J. (2011). Preschool onset Attention-Deficit/Hyperactivity Disorder: Course and predictors of stability over 24 months. Journal of Child and Adolescent Psychopharmacology, 21, 321–330. doi:10.1089/cap.2010.0045.
Tripp, G., Schaughency, E. A., & Clarke, B. (2006). Parent and teacher rating scales in the evaluation of Attention-Deficit/Hyperactivity Disorder: Contribution to diagnosis and differential diagnosis in clinically referred children. Journal of Developmental and Behavioral Pediatrics, 27, 209–218.
Vaurio, L., Riley, E. R., & Mattson, S. N. (2008). Differences in executive functioning in children with heavy prenatal alcohol exposure or attention-deficit/hyperactivity disorder. Journal of the International Neuropsychological Society, 14, 119–129.
Vernon-Feagans, L., Cox, M., & Investigators, F. L. P. K. (in press). The Family Life Project: An epidemiological and developmental study of young children living in poor rural communities Monographs of the Society for Research in Child Development
von Stauffenberg, C., & Campbell, S. B. (2007). Predicting the early developmental course of symptoms of Attention Deficit/Hyperactivity Disorder. Journal of Applied Developmental Psychology, 28, 536–552.
Wilens, T. E., Biederman, J., Brown, S., Tanguay, S., Monuteaux, M. C., Blake, C., et al. (2002). Psychiatric comorbidity and functioning in clinically referred preschool children and school-age youths with ADHD. Journal of the American Academy of Child and Adolescent Psychiatry, 41, 262–268.
Acknowledgments
Support for this research was provided by the National Institute of Child Health and Human Development grant P01 HD39667, with co-funding from the National Institute on Drug Abuse. The Family Life Project Key Investigators in the first phase of the study included Lynne Vernon-Feagans, Martha Cox, Clancy Blair, Peg Burchinal, Linda Burton, Keith Crnic, Ann Crouter, Patricia Garrett-Peters, Mark Greenberg, Stephanie Lanza, Roger Mills-Koonce, Cynthia Stifter, Emily Werner, and Michael Willoughby.
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Willoughby, M.T., Pek, J., Greenberg, M.T. et al. Parent-Reported Attention Deficit/Hyperactivity Symptomatology in Preschool-Aged Children: Factor Structure, Developmental Change, and Early Risk Factors. J Abnorm Child Psychol 40, 1301–1312 (2012). https://doi.org/10.1007/s10802-012-9641-8
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DOI: https://doi.org/10.1007/s10802-012-9641-8