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Research on Child and Adolescent Psychopathology

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01-10-2010

Alternative Factor Models and Heritability of the Short Leyton Obsessional Inventory—Children’s Version

Auteurs: Janette Moore, Gillian W. Smith, Mark Shevlin, Francis A. O’Neill

Gepubliceerd in: Research on Child and Adolescent Psychopathology | Uitgave 7/2010

Abstract

An alternative models framework was used to test three confirmatory factor analytic models for the Short Leyton Obsessional Inventory-Children’s Version (Short LOI-CV) in a general population sample of 517 young adolescent twins (11–16 years). A one-factor model as implicit in current classification systems of Obsessive–Compulsive Disorder (OCD), a two-factor obsessions and compulsions model, and a multidimensional model corresponding to the three proposed subscales of the Short LOI-CV (labelled Obsessions/Incompleteness, Numbers/Luck and Cleanliness) were considered. The three-factor model was the only model to provide an adequate explanation of the data. Twin analyses suggested significant quantitative sex differences in heritability for both the Obsessions/Incompleteness and Numbers/Luck dimensions with these being significantly heritable in males only (heritability of 60% and 65% respectively). The correlation between the additive genetic effects for these two dimensions in males was 0.95 suggesting they largely share the same genetic risk factors.

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Titel: Alternative Factor Models and Heritability of the Short Leyton Obsessional Inventory—Children’s Version
Auteurs: Janette Moore
Gillian W. Smith
Mark Shevlin
Francis A. O’Neill
Publicatiedatum: 01-10-2010
Uitgeverij: Springer US
Gepubliceerd in: Research on Child and Adolescent Psychopathology / Uitgave 7/2010
Print ISSN: 2730-7166
Elektronisch ISSN: 2730-7174
DOI: https://doi.org/10.1007/s10802-010-9414-1

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