Skip to main content
Top
Gepubliceerd in: Research on Child and Adolescent Psychopathology 2/2009

01-02-2009

Hypothalamic Pituitary Adrenal Axis Functioning in Reactive and Proactive Aggression in Children

Auteurs: Nestor L. Lopez-Duran, Sheryl L. Olson, Nastassia J. Hajal, Barbara T. Felt, Delia M. Vazquez

Gepubliceerd in: Research on Child and Adolescent Psychopathology | Uitgave 2/2009

Log in om toegang te krijgen
share
DELEN

Deel dit onderdeel of sectie (kopieer de link)

  • Optie A:
    Klik op de rechtermuisknop op de link en selecteer de optie “linkadres kopiëren”
  • Optie B:
    Deel de link per e-mail

Abstract

The purpose of this study was to examine the association between hypothalamic-pituitary-adrenal axis (HPA-axis) reactivity and proactive and reactive aggression in pre-pubertal children. After a 30-min controlled base line period, 73 7-year-old children (40 males and 33 females) were randomly assigned to one of two experimental tasks designed to elicit fear (N = 33) or frustration (N = 32), or a validity check condition (N = 8). This was followed by a 60-min controlled regulation phase. A total of 17 saliva samples for cortisol analysis were collected including 12 post-stress samples at 5-min intervals. Reactive and proactive aggression levels were assessed via the teacher-completed Aggression Behavior Teacher Checklist (Dodge and Coie, J Pers Soc Psychol, 53(6), 1146–1158, 1987). Reactive aggression significantly predicted total and peak post-stress cortisol regardless of stress modality. Proactive aggression was not a predictor of any cortisol index. Examination of pure reactive, proactive, combined, or non-aggressive children indicated that reactive aggressive children had higher cortisol reactivity than proactive and non-aggressive children. Our data suggest that while an overactive HPA-axis response to stress is associated with reactive aggression, stress induced HPA-axis variability does not seem to be related to proactive aggression.
Literatuur
go back to reference Achenbach, T. M. (1992). Manual for the child behavior checklist/2–3 and 1992 profile. Burlington: University of Vermont. Achenbach, T. M. (1992). Manual for the child behavior checklist/2–3 and 1992 profile. Burlington: University of Vermont.
go back to reference Allison, P. D. (1990). Change scores as dependent variables in regression analysis. Sociological Methodology, 20, 93–114.CrossRef Allison, P. D. (1990). Change scores as dependent variables in regression analysis. Sociological Methodology, 20, 93–114.CrossRef
go back to reference Anderson, C. A., & Bushman, B. J. (2002). Human aggression. Annual Review of Psychology, 53, 27–51.PubMedCrossRef Anderson, C. A., & Bushman, B. J. (2002). Human aggression. Annual Review of Psychology, 53, 27–51.PubMedCrossRef
go back to reference Atkins, M. S., Stoff, D. M., Osborne, M. L., & Brown, K. (1993). Distinguishing instrumental and hostile aggression: does it make a difference. Journal of Abnormal Child Psychology, 21(4), 355–365. doi:10.1007/BF01261598.PubMedCrossRef Atkins, M. S., Stoff, D. M., Osborne, M. L., & Brown, K. (1993). Distinguishing instrumental and hostile aggression: does it make a difference. Journal of Abnormal Child Psychology, 21(4), 355–365. doi:10.​1007/​BF01261598.PubMedCrossRef
go back to reference Cicchetti, D., & Rogosch, F. A. (2001). The impact of child maltreatment and psychopathology on neuroendocrine functioning. Development and Psychopathology, 13(4), 783–804.PubMed Cicchetti, D., & Rogosch, F. A. (2001). The impact of child maltreatment and psychopathology on neuroendocrine functioning. Development and Psychopathology, 13(4), 783–804.PubMed
go back to reference Clow, A., Thorn, L., Evans, P., & Hucklebridge, F. (2004). The awakening cortisol response: methodological issues and significance. Stress (Amsterdam, Netherlands), 7(1), 29–37. doi:10.1080/10253890410001667205. Clow, A., Thorn, L., Evans, P., & Hucklebridge, F. (2004). The awakening cortisol response: methodological issues and significance. Stress (Amsterdam, Netherlands), 7(1), 29–37. doi:10.​1080/​1025389041000166​7205.
go back to reference de Kloet, E. R. (1991). Brain corticosteroid receptor balance and homeostatic control. Frontiers in Neuroendocrinology, 12(2), 95–164. de Kloet, E. R. (1991). Brain corticosteroid receptor balance and homeostatic control. Frontiers in Neuroendocrinology, 12(2), 95–164.
go back to reference de Rooij, S. R., Painter, R. C., Phillips, D. I. W., Osmond, C., Tanck, M. W. T., Bossuyt, P. M. M., et al. (2006). Cortisol responses to psychological stress in adults after prenatal exposure to the Dutch famine. Psychoneuroendocrinology, 31(10), 1257–1265. doi:10.1016/j.psyneuen.2006.09.007.PubMedCrossRef de Rooij, S. R., Painter, R. C., Phillips, D. I. W., Osmond, C., Tanck, M. W. T., Bossuyt, P. M. M., et al. (2006). Cortisol responses to psychological stress in adults after prenatal exposure to the Dutch famine. Psychoneuroendocrinology, 31(10), 1257–1265. doi:10.​1016/​j.​psyneuen.​2006.​09.​007.PubMedCrossRef
go back to reference Dodge, K. A. (1991). The structure and function of proactive and reactive aggression. In D. J. Pepler, & K. H. Rubin (Eds.), The development and treatment of childhood aggression (pp. 201–218). Hillsdale, NJ: Erlbaum. Dodge, K. A. (1991). The structure and function of proactive and reactive aggression. In D. J. Pepler, & K. H. Rubin (Eds.), The development and treatment of childhood aggression (pp. 201–218). Hillsdale, NJ: Erlbaum.
go back to reference Dodge, K. A., & Coie, J. D. (1987). Social-information-processing factors in reactive and proactive aggression in children’s peer groups. Journal of Personality and Social Psychology, 53(6), 1146–1158.PubMedCrossRef Dodge, K. A., & Coie, J. D. (1987). Social-information-processing factors in reactive and proactive aggression in children’s peer groups. Journal of Personality and Social Psychology, 53(6), 1146–1158.PubMedCrossRef
go back to reference Dodge, K. A., Lochman, J. E., Harnish, J. D., & Bates, J. E. (1997). Reactive and proactive aggression in school children and psychiatrically impaired chronically assaultive youth. Journal of Abnormal Psychology, 106(1), 37–51. doi:10.1037/0021-843X.106.1.37.PubMedCrossRef Dodge, K. A., Lochman, J. E., Harnish, J. D., & Bates, J. E. (1997). Reactive and proactive aggression in school children and psychiatrically impaired chronically assaultive youth. Journal of Abnormal Psychology, 106(1), 37–51. doi:10.​1037/​0021-843X.​106.​1.​37.PubMedCrossRef
go back to reference Gerra, G., Zaimovic, A., Avanzini, P., & Chittolini, B. (1997). Neurotransmitter–neuroendocrine responses to experimentally induced aggression in humans: influence of personality variable. Psychiatry Research, 66(1), 33–43. doi:10.1016/S0165-1781(96)02965-4.PubMedCrossRef Gerra, G., Zaimovic, A., Avanzini, P., & Chittolini, B. (1997). Neurotransmitter–neuroendocrine responses to experimentally induced aggression in humans: influence of personality variable. Psychiatry Research, 66(1), 33–43. doi:10.​1016/​S0165-1781(96)02965-4.PubMedCrossRef
go back to reference Kabbaj, M., Devine, D. P., Savage, V. R., & Akil, H. (2000). Neurobiological correlates of individual differences in novelty-seeking behavior in the rat: differential expression of stress-related molecules. The Journal of Neuroscience, 20(18), 6983–6988.PubMed Kabbaj, M., Devine, D. P., Savage, V. R., & Akil, H. (2000). Neurobiological correlates of individual differences in novelty-seeking behavior in the rat: differential expression of stress-related molecules. The Journal of Neuroscience, 20(18), 6983–6988.PubMed
go back to reference Kalin, N. H. (1999a). Primate models and aggression. Journal of Clinical Psychiatry Monograph Series, 17(2), 22–24. Kalin, N. H. (1999a). Primate models and aggression. Journal of Clinical Psychiatry Monograph Series, 17(2), 22–24.
go back to reference Kalin, N. H. (1999b). Primate models to understand human aggression. Journal of Clinical Psychiatry, 60(15), 29–32.PubMed Kalin, N. H. (1999b). Primate models to understand human aggression. Journal of Clinical Psychiatry, 60(15), 29–32.PubMed
go back to reference Kempes, M., de Vries, H., Matthys, W., van Engeland, H., & van Hoof, J. (2008). Differences in cortisol response affect the distinction of observed reactive and proactive aggression in children with aggressive behaviour disorders. Journal of Neural Transmission, 115(1), 139–147. doi:10.1007/s00702-007-0810-9.PubMedCrossRef Kempes, M., de Vries, H., Matthys, W., van Engeland, H., & van Hoof, J. (2008). Differences in cortisol response affect the distinction of observed reactive and proactive aggression in children with aggressive behaviour disorders. Journal of Neural Transmission, 115(1), 139–147. doi:10.​1007/​s00702-007-0810-9.PubMedCrossRef
go back to reference Little, T. D., Jones, S. M., Henrich, C. C., & Hawley, P. H. (2003). Disentangling the “whys” from the “whats” of aggressive behaviour. International Journal of Behavioral Development, 27(2), 122–133. doi:10.1080/01650250244000128.CrossRef Little, T. D., Jones, S. M., Henrich, C. C., & Hawley, P. H. (2003). Disentangling the “whys” from the “whats” of aggressive behaviour. International Journal of Behavioral Development, 27(2), 122–133. doi:10.​1080/​0165025024400012​8.CrossRef
go back to reference Mathews, J. N., Altman, D. G., Campbell, M. J., & Royston, P. (1990). Analysis of serial measurements in medical research. British Medical Journal, 300(6719), 230–235.CrossRef Mathews, J. N., Altman, D. G., Campbell, M. J., & Royston, P. (1990). Analysis of serial measurements in medical research. British Medical Journal, 300(6719), 230–235.CrossRef
go back to reference McBurnett, K., Lahey, B. B., Frick, P. J., & Risch, C. (1991). Anxiety, inhibition, and conduct disorder in children: II. Relation to salivary cortisol. Journal of the American Academy of Child and Adolescent Psychiatry, 30(2), 192–196. doi:10.1097/00004583-199103000-00005.PubMedCrossRef McBurnett, K., Lahey, B. B., Frick, P. J., & Risch, C. (1991). Anxiety, inhibition, and conduct disorder in children: II. Relation to salivary cortisol. Journal of the American Academy of Child and Adolescent Psychiatry, 30(2), 192–196. doi:10.​1097/​00004583-199103000-00005.PubMedCrossRef
go back to reference Moss, H. B., Yanyukov, M., Yao, J. K., & Kirillova, G. P. (1999). Salivary cortisol responses in prepubertal boys: the effects of parental substance abuse and association with drug use behavior during adolescence. Biological Psychiatry, 45(10), 1293–1299. doi:10.1016/S0006-3223(98)00216-9.PubMedCrossRef Moss, H. B., Yanyukov, M., Yao, J. K., & Kirillova, G. P. (1999). Salivary cortisol responses in prepubertal boys: the effects of parental substance abuse and association with drug use behavior during adolescence. Biological Psychiatry, 45(10), 1293–1299. doi:10.​1016/​S0006-3223(98)00216-9.PubMedCrossRef
go back to reference Muñoz, L. C., Frick, P. J., Kimonis, E. R., & Auccoin, K. J. (2008). Types of aggression, responsiveness to provocation, and callous-unemotional traits in detained adolescents. Journal of Abnormal Child Psychology, 36(1), 15–28. doi:10.1007/s10802-007-9137-0.PubMedCrossRef Muñoz, L. C., Frick, P. J., Kimonis, E. R., & Auccoin, K. J. (2008). Types of aggression, responsiveness to provocation, and callous-unemotional traits in detained adolescents. Journal of Abnormal Child Psychology, 36(1), 15–28. doi:10.​1007/​s10802-007-9137-0.PubMedCrossRef
go back to reference Nouvion, S. O., Cherek, D. R., Lane, S. D., Tcheremissine, O. V., & Lieving, L. M. (2007). Human proactive aggression: association with personality disorders and psychopathy. Aggressive Behavior, 33(6), 552–562. doi:10.1002/ab.20220.PubMedCrossRef Nouvion, S. O., Cherek, D. R., Lane, S. D., Tcheremissine, O. V., & Lieving, L. M. (2007). Human proactive aggression: association with personality disorders and psychopathy. Aggressive Behavior, 33(6), 552–562. doi:10.​1002/​ab.​20220.PubMedCrossRef
go back to reference Olson, S. L., & Sameroff, A. J. (1997). Social risk and self-regulation problems in early childhood. Bethesda, MD: National Institute of Mental Health. Olson, S. L., & Sameroff, A. J. (1997). Social risk and self-regulation problems in early childhood. Bethesda, MD: National Institute of Mental Health.
go back to reference Orobio de Castro, B., Brendgen, M., Van Boxtel, H., Vitaro, F., & Schaepers, L. (2007). “Accept me, or else”: disputed overestimation of social competence predicts increases in proactive aggression. Journal of Abnormal Child Psychology, 35(2), 165–178. doi:10.1007/s10802-006-9063-6.PubMedCrossRef Orobio de Castro, B., Brendgen, M., Van Boxtel, H., Vitaro, F., & Schaepers, L. (2007). “Accept me, or else”: disputed overestimation of social competence predicts increases in proactive aggression. Journal of Abnormal Child Psychology, 35(2), 165–178. doi:10.​1007/​s10802-006-9063-6.PubMedCrossRef
go back to reference Scerbo, A. S., & Kolko, D. J. (1994). Salivary testosterone and cortisol in disruptive children: relationship to aggressive, hyperactive, and internalizing behaviors. Journal of the American Academy of Child and Adolescent Psychiatry, 33(8), 1174–1184. doi:10.1097/00004583-199410000-00013.PubMedCrossRef Scerbo, A. S., & Kolko, D. J. (1994). Salivary testosterone and cortisol in disruptive children: relationship to aggressive, hyperactive, and internalizing behaviors. Journal of the American Academy of Child and Adolescent Psychiatry, 33(8), 1174–1184. doi:10.​1097/​00004583-199410000-00013.PubMedCrossRef
go back to reference Schwartz, D., Dodge, K. A., Coie, J. D., Hubbard, J. A., Cillessen, A. H., Lamerise, E. A., et al. (1998). Social-cognitive and behavioral correlates of aggression and victimization in boys’ play groups. Journal of Abnormal Child Psychology, 26(6), 431–440. doi:10.1023/A:1022695601088.PubMedCrossRef Schwartz, D., Dodge, K. A., Coie, J. D., Hubbard, J. A., Cillessen, A. H., Lamerise, E. A., et al. (1998). Social-cognitive and behavioral correlates of aggression and victimization in boys’ play groups. Journal of Abnormal Child Psychology, 26(6), 431–440. doi:10.​1023/​A:​1022695601088.PubMedCrossRef
go back to reference Tennes, K., & Kreye, M. (1985). Children’s adrenocortical responses to classroom activities and tests in elementary school. Psychosomatic Medicine, 47(5), 451–460.PubMed Tennes, K., & Kreye, M. (1985). Children’s adrenocortical responses to classroom activities and tests in elementary school. Psychosomatic Medicine, 47(5), 451–460.PubMed
go back to reference Tennes, K., Kreye, M., Avitable, N., & Wells, R. (1986). Behavioral correlates of excreted catecholamines and cortisol in second-grade children. Journal of the American Academy of Child Psychiatry, 25(6), 764–770.PubMedCrossRef Tennes, K., Kreye, M., Avitable, N., & Wells, R. (1986). Behavioral correlates of excreted catecholamines and cortisol in second-grade children. Journal of the American Academy of Child Psychiatry, 25(6), 764–770.PubMedCrossRef
go back to reference Van Bokhoven, I., Van Goozen, S. M., van Engeland, H., Schaal, B., Arseneault, L., Séguin, J. R., et al. (2005). Salivary cortisol and aggression in a population-based longitudinal study of adolescent males. Journal of Neural Transmission, 112(8), 1083–1096. doi:10.1007/s00702-004-0253-5.PubMedCrossRef Van Bokhoven, I., Van Goozen, S. M., van Engeland, H., Schaal, B., Arseneault, L., Séguin, J. R., et al. (2005). Salivary cortisol and aggression in a population-based longitudinal study of adolescent males. Journal of Neural Transmission, 112(8), 1083–1096. doi:10.​1007/​s00702-004-0253-5.PubMedCrossRef
go back to reference Van Goozen, S. M., Matthys, W., Cohen-Kettenis, P. T., Gispen-de Wied, C., Wiegant, V. M., & van Engeland, H. (1998). Salivary cortisol and cardiovascular activity during stress in oppositional-defiant disorder boys and normal controls. Biological Psychiatry, 43(7), 531–539. doi:10.1016/S0006-3223(97)00253-9.PubMedCrossRef Van Goozen, S. M., Matthys, W., Cohen-Kettenis, P. T., Gispen-de Wied, C., Wiegant, V. M., & van Engeland, H. (1998). Salivary cortisol and cardiovascular activity during stress in oppositional-defiant disorder boys and normal controls. Biological Psychiatry, 43(7), 531–539. doi:10.​1016/​S0006-3223(97)00253-9.PubMedCrossRef
go back to reference Vitaro, F., Brendgen, M., & Tremblay, R. E. (2002). Reactively and proactively aggressive children: antecedent and subsequent characteristics. Journal of Child Psychology and Psychiatry, and Allied Disciplines, 43(4), 495–505. doi:10.1111/1469-7610.00040.PubMedCrossRef Vitaro, F., Brendgen, M., & Tremblay, R. E. (2002). Reactively and proactively aggressive children: antecedent and subsequent characteristics. Journal of Child Psychology and Psychiatry, and Allied Disciplines, 43(4), 495–505. doi:10.​1111/​1469-7610.​00040.PubMedCrossRef
go back to reference Vitaro, F., Gendreau, P. L., Tremblay, R. E., & Oligny, P. (1998). Reactive and proactive aggression differentially predict later conduct problems. Journal of Child Psychology and Psychiatry, and Allied Disciplines, 39(3), 377–385. doi:10.1017/S0021963097002102.PubMedCrossRef Vitaro, F., Gendreau, P. L., Tremblay, R. E., & Oligny, P. (1998). Reactive and proactive aggression differentially predict later conduct problems. Journal of Child Psychology and Psychiatry, and Allied Disciplines, 39(3), 377–385. doi:10.​1017/​S002196309700210​2.PubMedCrossRef
Metagegevens
Titel
Hypothalamic Pituitary Adrenal Axis Functioning in Reactive and Proactive Aggression in Children
Auteurs
Nestor L. Lopez-Duran
Sheryl L. Olson
Nastassia J. Hajal
Barbara T. Felt
Delia M. Vazquez
Publicatiedatum
01-02-2009
Uitgeverij
Springer US
Gepubliceerd in
Research on Child and Adolescent Psychopathology / Uitgave 2/2009
Print ISSN: 2730-7166
Elektronisch ISSN: 2730-7174
DOI
https://doi.org/10.1007/s10802-008-9263-3

Andere artikelen Uitgave 2/2009

Research on Child and Adolescent Psychopathology 2/2009 Naar de uitgave