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Paternal Age and Epilepsy in the Offspring

  • Neurological Diseases
  • Published:
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Abstract

Advanced paternal age is associated with a higher rate of de novo mutation in sperm cells and mental disorders in the offspring. In a population based cohort study of 96,654 children, we found that fathers aged 35 years or more were slightly more likely to have a child diagnosed with epilepsy compared to fathers aged 25–29 years. Our data suggest a modest paternal effect on the aetiology of epilepsy.

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Authors and Affiliations

  1. The Danish Epidemiology Science Centre, Institute of Public Health, Department of Epidemiology, University of Aarhus, DK-8000, Aarhus C, Denmark

    Mogens Vestergaard, Alissa Mork, Kreesten M. Madsen & Jørn Olsen

  2. Division of Environmental and Occupational Health, University of Minnesota School of Public Health, Minneapolis, MN, 55455, USA

    Alissa Mork

  3. Department of Epidemiology, UCLA School of Public Health, Los Angeles, CA, 90095-1772, USA

    Jørn Olsen

Authors
  1. Mogens Vestergaard
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  2. Alissa Mork
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  3. Kreesten M. Madsen
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  4. Jørn Olsen
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Corresponding author

Correspondence to Mogens Vestergaard.

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Vestergaard, M., Mork, A., Madsen, K.M. et al. Paternal Age and Epilepsy in the Offspring. Eur J Epidemiol 20, 1003–1005 (2005). https://doi.org/10.1007/s10654-005-4250-2

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  • DOI: https://doi.org/10.1007/s10654-005-4250-2

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