Skip to main content

Advertisement

Log in

Quality of Life in Psychosis: Prevalence and Associated Factors in a Nigerian Clinical Population

  • Brief Communication
  • Published:
Community Mental Health Journal Aims and scope Submit manuscript

Abstract

Aim of the study was to assess sociodemographic and clinical determinants of quality of life in psychotic patients in a general hospital population in Nigeria. Information was obtained on demography, duration of untreated illness (DUI) and functioning among Schizophrenia (368), schizoaffective disorder (70), and 214 patients with affective psychosis. Functioning was assessed using GAF, severity of psychopathology with PANSS and quality of life using WHOQoL-BREF. In general, the differences in the QoL across the three psychotic disorders were small. Linear regression analysis, showed that high GAF p < 0.001, medication adherence, p = 0.007 were associated with good QoL in schizophrenia, low PANSS p < 0.001 and short DUI p = 0.001 in schizoaffective disorder and low PANSS, high GAF p < 0.001 respectively in affective psychosis. QoL and its determinants in psychosis are not absolutely different. More research is required in this area.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  • Adewuya, A., & Ola, A. (2008). Medication adherence in Nigerian patients with bipolar disorder. Schizophrenia Research, 98, 193–199.

    Google Scholar 

  • American Psychiatric Association. (1994). Diagnostic and statistical manual of mental disorders (4th ed.). Washington DC: A. P. Association.

    Google Scholar 

  • Andreasen, N. C., Endicott, J., Spitzer, R. L., & Winokur, G. (1977). The family history method using diagnostic criteria: Reliability and validity. [Comparative Study Research Support, US Gov’t, Non-P H S]. Archives of General Psychiatry, 34(10), 1229–1235.

    Article  CAS  PubMed  Google Scholar 

  • Bebbington, P., & Nayati, T. (1994). The psychosis screening questionnaire. International Journal of Methods in Psychiatric Research, 5, 11–19.

    Google Scholar 

  • Bellivier, F., Geoffroy, P. A., Scott, J., Schurhoff, F., Leboyer, M., & Etain, B. (2013). Biomarkers of bipolar disorder: Specific or shared with schizophrenia? [Review]. Front Biosci, 5, 845–863.

    Article  Google Scholar 

  • Briggs, A., Wild, D., Lees, M., Reaney, M., Dursun, S., Parry, D., & Mukherjee, J. (2008). Impact of schizophrenia and schizophrenia treatment-related adverse events on quality of life: Direct utility elicitation [Research Support, Non-US Gov’t]. Health Qual Life Outcomes, 6(105), 1477–7525.

    Google Scholar 

  • Browne, S., Roe, M., Lane, A., Gervin, M., Morris, M., Kinsella, A., et al. (1996). Quality of life in schizophrenia: Relationship to sociodemographic factors, symptomatology and tardive dyskinesia [Comparative Study Research Support, Non-US Gov’t]. Acta Psychiatrica Scandinavica, 94(2), 118–124.

    Article  CAS  PubMed  Google Scholar 

  • Choi, M. R., Eun, H. J., Yoo, T. P., Yun, Y., Wood, C., Kase, M., et al. (2012). The effects of sociodemographic factors on psychiatric diagnosis. Psychiatry Investigation, 9(3), 199–208.

    Article  PubMed Central  PubMed  Google Scholar 

  • Endicott, J., Spitzer, R. L., Fleiss, J. L., & Cohen, J. (1976). The global assessment scale. A procedure for measuring overall severity of psychiatric disturbance [Comparative Study Research Support, US Gov’t, Non-P H S]. Archives of General Psychiatry, 33(6), 766–771.

    Article  CAS  PubMed  Google Scholar 

  • Fan, X., Henderson, D. C., Chiang, E., Briggs, L. B., Freudenreich, O., Evins, A. E., et al. (2007). Sexual functioning, psychopathology and quality of life in patients with schizophrenia [Research Support, NIH, Extramural]. Schizophrenia Research, 94(1–3), 119–127.

    Article  PubMed  Google Scholar 

  • First, M., Spitzer, R., Gibbon, M., & Williams, J. (1996). Structured Clinical Interview for DSM-IV Axis I Disorders, Clinical Version, (SCID-CV). Washington, DC: American Psychiatric Press, Inc.

    Google Scholar 

  • Goldman, H. H., Skodol, A. E., & Lave, T. R. (1992). Revising axis V for DSM-IV: A review of measures of social functioning. [Review]. American Journal of Psychiatry, 149(9), 1148–1156.

    Article  CAS  PubMed  Google Scholar 

  • Gureje, O., & Lasebikan, V. O. (2006). Use of mental health services in a developing country. Results from the Nigerian survey of mental health and well-being. Social Psychiatry and Psychiatric Epidemiology, 41(1), 44–49.

    Article  PubMed  Google Scholar 

  • Hayhurst, K. P., Drake, R. J., Massie, J. A., Dunn, G., Barnes, T. R., Jones, P. B., & Lewis, S. W. (2014). Improved quality of life over one year is associated with improved adherence in patients with schizophrenia. European Psychiatry, 29(3), 191–196.

    Article  CAS  PubMed  Google Scholar 

  • Herrman, H., Hawthorne, G., & Thomas, R. (2002). Quality of life assessment in people living with psychosis [Research Support, Non-US Gov’t]. Social Psychiatry and Psychiatric Epidemiology, 37(11), 510–518.

    Article  PubMed  Google Scholar 

  • Kao, Y. C., Liu, Y. P., Chou, M. K., & Cheng, T. H. (2011). Subjective quality of life in patients with chronic schizophrenia: Relationships between psychosocial and clinical characteristics. Comprehensive Psychiatry, 52(2), 171–180.

    Article  PubMed  Google Scholar 

  • Law, C. W., Chen, E. Y., Cheung, E. F., Chan, R. C., Wong, J. G., Lam, C. L., et al. (2005). Impact of untreated psychosis on quality of life in patients with first-episode schizophrenia. Quality of Life Research, 14(8), 1803–1811.

    Article  CAS  PubMed  Google Scholar 

  • Lay, B., Schmidt, M. H., & Blanz, B. (1997). Course of adolescent psychotic disorder with schizoaffective episodes. European Child and Adolescent Psychiatry, 6(1), 32–41.

    Article  CAS  PubMed  Google Scholar 

  • Malm, U., May, P. R., & Dencker, S. J. (1981). Evaluation of the quality of life of the schizophrenic outpatient: A checklist [Research Support, Non-US Gov’t]. Schizophrenia Bulletin, 7(3), 477–487.

    Article  CAS  PubMed  Google Scholar 

  • Marrag, I., Hajji, K., Hadj, A. M., Zarrouk, L., Kachouri, R., & Nasr, M. (2014). Bipolar disorder and quality of life: A cross-sectional study including 104 Tunisian patients. Encephale, 17(14), 00153–00155.

    Google Scholar 

  • Morisky, D. E., Green, L. W., & Levine, D. M. (1986). Concurrent and predictive validity of a self-reported measure of medication adherence [Research Support, US Gov’t, P H S]. Medical Care, 24(1), 67–74.

    Article  CAS  PubMed  Google Scholar 

  • Overall, J. E., & Gorham, D. R. (1962). The brief psychiatric rating scale. Psychological Reports, 10(3), 799–812. doi:10.2466/pr0.1962.10.3.799.

    Article  Google Scholar 

  • Renwick, L., Jackson, D., Foley, S., Owens, E., Ramperti, N., Behan, C., et al. (2012). Depression and quality of life in first-episode psychosis. Comprehensive Psychiatry, 53(5), 451–455.

    Article  PubMed  Google Scholar 

  • Ritsner, M., Kurs, R., Gibel, A., Ratner, Y., & Endicott, J. (2005). Validity of an abbreviated quality of life enjoyment and satisfaction questionnaire (Q-LES-Q-18) for schizophrenia, schizoaffective, and mood disorder patients [Validation Studies]. Quality of Life Research, 14(7), 1693–1703.

    Article  PubMed  Google Scholar 

  • Ruaf Foundation. Ibadan (Nigeria), from http://www.ruaf.org/node/1517.

  • Saarni, S. I., Viertiö, S., Perälä, J., Koskinen, S., Lönnqvist, J., & Suvisaari, J. (2010). Quality of life of people with schizophrenia, bipolar disorder and other psychotic disorders. The British Journal of Psychiatry, 197(5), 386–394. doi:10.1192/bjp.bp.109.076489.

    Article  PubMed  Google Scholar 

  • Singh, M. M., & Kay, S. R. (1975). A comparative study of haloperidol and chlorpromazine in terms of clinical effects and therapeutic reversal with benztropine in schizophrenia. Theoretical implications for potency differences among neuroleptics. [Clinical Trial Comparative Study Controlled Clinical Trial]. Psychopharmacologia, 43(2), 103–113.

    Article  CAS  PubMed  Google Scholar 

  • Solanki, R. K., Singh, P., Midha, A., & Chugh, K. (2008). Schizophrenia: Impact on quality of life. Indian Jornal of Psychiatry, 50(3), 181–186.

    Article  Google Scholar 

  • SPSS Inc. Released 2004. SPSS for windows, version 13.0. Chicago, SPSS Inc.

  • Wegener, S., Redoblado-Hodge, M. A., Lucas, S., Fitzgerald, D., Harris, A., & Brennan, J. (2005). Relative contributions of psychiatric symptoms and neuropsychological functioning to quality of life in first-episode psychosis. Australian and New Zealand Journal of Psychiatry, 39(6), 487–492.

    Article  PubMed  Google Scholar 

  • WHOQOLGROUP. (1996). WHOQOL-BREF. Field Trial Version. Program on Mental Health. Geneva, Switzerland: World Health Organization.

  • Wittchen, H. U., Hofler, M., & Meister, W. (2001). Prevalence and recognition of depressive syndromes in German primary care settings: Poorly recognized and treated? [Research Support, Non-US Gov’t]. International Clinical Psychopharmacology, 16(3), 121–135.

    Article  CAS  PubMed  Google Scholar 

  • Yen, C. F., Cheng, C. P., Huang, C. F., Yen, J. Y., Ko, C. H., & Chen, C. S. (2008). Quality of life and its association with insight, adverse effects of medication and use of atypical antipsychotics in patients with bipolar disorder and schizophrenia in remission [Comparative Study Research Support, Non-US Gov’t]. Bipolar Disorders, 10(5), 617–624.

    Article  PubMed  Google Scholar 

Download references

Acknowledgments

We acknowledge all our secretariat staffs and Dr. OO Ayinde (UCH) Ibadan for their support in various ways. This study was funded by New World Psychiatric Hospital Ibadan, Nigeria.

Conflict of interest

None.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to V. O. Lasebikan.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Lasebikan, V.O., Owoaje, E.T. Quality of Life in Psychosis: Prevalence and Associated Factors in a Nigerian Clinical Population. Community Ment Health J 51, 491–496 (2015). https://doi.org/10.1007/s10597-015-9842-z

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10597-015-9842-z

Keywords

Navigation