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Child Psychiatry & Human Development
Gepubliceerd in: Child Psychiatry & Human Development 1/2018

07-04-2017 | Original Article

An Initial Case Series of Intensive Cognitive–Behavioral Therapy for Obsessive–Compulsive Disorder in Adolescents with Autism Spectrum Disorder

Auteurs: Marina Iniesta-Sepúlveda, Joshua M. Nadeau, Amaya Ramos, Brian Kay, Bradley C. Riemann, Eric A. Storch

Gepubliceerd in: Child Psychiatry & Human Development | Uitgave 1/2018

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Abstract

Obsessive–compulsive disorder (OCD) is prevalent among youth with autism spectrum disorder (ASD). Cognitive–behavioral therapy (CBT) with ASD-specific modifications has support for treating OCD in this population; however, use of intensive CBT in youth with ASD and severe OCD has not been tested. The current study examined the preliminary effectiveness of an individualized intensive CBT protocol for OCD in adolescents with ASD. Nine adolescents (aged 11–17 years) completed a regimen of intensive CBT (range 24–80 daily sessions) incorporating exposure with response prevention (ERP). Treatment materials, language and techniques were modified in accordance with evidence-based findings for this population. Seven of nine participants (78%) were treatment responders, and large treatment effects (d = 1.35–2.58) were obtained on primary outcomes (e.g., obsessive–compulsive symptom severity). Preliminary findings suggest that an intensive CBT approach for OCD is effective among adolescents with ASD.
vorige artikel The Strengths and Difficulties Questionnaire-Parents for Italian School-Aged Children: Psychometric Properties and Norms
volgende artikel Testing a Higher Order Model of Internalizing and Externalizing Behavior: The Role of Aggression Subtypes
Literatuur
1.
American Psychiatric Association (2013) Diagnostic and statistical manual of mental disorders, 5th edn. American Psychiatric Publishing, Washington DCCrossRef
2.
Centers for Disease Control and Prevention. (2014) Prevalence of autism spectrum disorder among children aged 8 years: autism and developmental disabilities monitoring network. MMWR Surveill Summ 63:1–21
3.
Dean M, Kasari C, Shih W, Frankel F, Whitney R, Landa R et al (2014) The peer relationships of girls with ASD at school: comparison to boys and girls with and without ASD. J Child Psychol Psychiatry 55:1218–1225CrossRefPubMed
4.
Smith LE, Greenberg JS, Mailick MR (2014) The family context of autism spectrum disorders: influence on the behavioral phenotype and quality of life. Child Adolesc Psychiatr Clin N Am 23:143–155CrossRefPubMed
5.
Joshi G, Petty C, Wozniak J, Henin A, Fried R, Galdo M et al (2010) The heavy burden of psychiatric comorbidity in youth with autism spectrum disorders: a large comparative study of a psychiatrically referred population. J Autism Dev Disord 40:1361–1370CrossRefPubMed
6.
Posserud M, Hysing M, Helland W, Gillberg C, Lundervold AJ (2016) Autism traits: the importance of “co-morbid” problems for impairment and contact with services. Data from the Bergen Child Study. Res Dev Disabil. doi:10.​1016/​j.​ridd.​2016.​01.​002 PubMed
7.
Leyfer OT, Folstein SE, Bacalman S, Davis NO, Dinh E, Morgan J et al (2006) Comorbid psychiatric disorders in children with autism: interview development and rates of disorders. J Autism Dev Disord 36:849–861CrossRefPubMed
8.
Bellini S (2004) Social skill deficits and anxiety in high-functioning adolescents with autism spectrum disorders. Focus Autism Other Dev Disabl 19:78–86CrossRef
9.
Lewin AB, Wood JJ, Gunderson S, Murphy TK, Storch EA (2011) Phenomenology of comorbid autism spectrum and obsessive–compulsive disorders among children. J Dev Phys Disabil 23:543–553CrossRef
10.
McGuire JF, Piacentini J, Lewin AB, Brennan EA, Murphy TK, Storch EA (2015) A meta-analysis of cognitive behavior therapy and medication for child obsessive–compulsive disorder: moderators of treatment effectiveness, response, and remission. Depress Anxiety 32:580–593CrossRefPubMedPubMedCentral
11.
Sánchez-Meca J, Rosa-Alcázar AI, Iniesta-Sepúlveda M, Rosa-Alcázar Á (2014) Differential efficacy of cognitive–behavioral therapy and pharmacological treatments for pediatric obsessive–compulsive disorder: a meta-analysis. J Anxiety Disord 28:31–44CrossRefPubMed
12.
Geller DA, Biederman J, Stewart SE, Mullin B, Farrell C, Wagner KD (2003) Impact of comorbidity on treatment response to paroxetine in pediatric obsessive–compulsive disorder: is the use of exclusion criteria empirically supported in randomized clinical trials? J Child Adolesc Psychopharmacol 13:19–29CrossRef
13.
Storch EA, Merlo LJ, Larson MJ, Geffken GR, Lehmkuhl HD, Jacob ML (2008) Impact of comorbidity on cognitive–behavioral therapy response in pediatric obsessive–compulsive disorder. J Am Acad Child Adolesc Psychiatry 47:583–592CrossRefPubMed
14.
Storch EA, Björgvinsson T, Riemann B, Lewin AB, Morales MJ, Murphy TK (2010) Factors associated with poor response in cognitive–behavioral therapy for pediatric obsessive–compulsive disorder. Bull Menninger Clin 74:167CrossRefPubMed
15.
Ung D, Selles R, Small BJ, Storch EA (2015) A systematic review and meta-analysis of cognitive–behavioral therapy for anxiety in youth with high-functioning autism spectrum disorders. Child Psychiatry Hum Dev 46:533–547CrossRefPubMed
16.
Sofronoff K, Attwood T, Hinton S (2005) A randomized controlled trial of a CBT intervention for anxiety in children with Asperger syndrome. J Child Psychol Psychiatry 46:1152–1160CrossRefPubMed
17.
Reaven JA, Blakeley-Smith A, Nichols S, Dasari M, Flanigan E, Hepburn S (2009) Cognitive–behavioral group treatment for anxiety symptoms in children with high-functioning autism spectrum disorders a pilot study. Focus Autism Other Dev Disabl 24:27–37CrossRef
18.
White SW, Albano AM, Johnson CR, Kasari C, Ollendick T, Klin A (2010) Development of a cognitive–behavioral intervention program to treat anxiety and social deficits in teens with high-functioning autism. Clin Child Fam Psychol Rev 13:77–90CrossRefPubMedPubMedCentral
19.
Storch EA, Lewin AB, Collier AB, Arnold E, De Nadai AS, Dane BF (2014) A randomized controlled trial of cognitive–behavioral therapy versus treatment as usual for adolescents with autism spectrum disorders and comorbid anxiety. ‎Depress Anxiety 32:174–181CrossRefPubMedPubMedCentral
20.
Sze KM, Wood JJ (2007) Cognitive behavioral treatment of comorbid anxiety disorders and social difficulties in children with high-functioning autism: a case report. J Contemp Psychother 37:133–143CrossRef
21.
Wood JJ, Drahota A, Sze K, Har K, Chiu A, Langer DA (2009) Cognitive behavioral therapy for anxiety in children with autism spectrum disorders: a randomized, controlled trial. J Child Psychol Psychiatry 50:224–234CrossRefPubMedPubMedCentral
22.
Wood JJ, Ehrenreich-May J, Alessandri M, Fujii C, Renno P, Laugeson E (2015) Cognitive behavioral therapy for early adolescents with autism spectrum disorders and clinical anxiety: a randomized, controlled trial. Behav Ther 46:7–19CrossRefPubMed
23.
White SW, Ollendick T, Albano AM, Oswald D, Johnson C, Southam-Gerow MA (2013) Randomized controlled trial: multimodal anxiety and social skill intervention for adolescents with autism spectrum disorder. ‎J Autism Dev Disord 43:382–394CrossRefPubMedPubMedCentral
24.
El-Ghoroury NH, Krackow E (2011) A developmental–behavioral approach to outpatient psychotherapy with children with autism spectrum disorders. J Contemp Psychother 41:11–17CrossRef
25.
Elliott SJ, Fitzsimons L (2014) Modified CBT for treatment of OCD in a 7-year-old boy with ASD—a case report. J Child Adolesc Psychiatr Nurs 27:156–159CrossRefPubMed
26.
Lehmkuhl HD, Storch EA, Bodfish JW, Geffken GR (2008) Brief report: exposure and response prevention for obsessive compulsive disorder in a 12-year-old with autism. J Autism Dev Disord 38:977–981CrossRefPubMedPubMedCentral
27.
Nadeau JM, Arnold EB, Storch EA, Lewin AB (2014) Family cognitive–behavioral treatment for a child with autism and comorbid obsessive compulsive disorder. ‎Clin Case Stud 13:22–36CrossRef
28.
Reaven J, Hepburn S (2003) Cognitive–behavioral treatment of obsessive–compulsive disorder in a child with asperger syndrome:a case report. Autism 7:145–164CrossRefPubMed
29.
Rooney M, Alfano CA, Walsh KS, Parr AF (2011) Differential diagnosis and treatment of obsessive–compulsive, inattentive, and sleep symptoms in a 7-year-old with PDD-NOS. Clin Case Stud 10:133–146CrossRef
30.
Murray K, Jassi A, Mataix-Cols D, Barrow F, Krebs G (2015) Outcomes of cognitive behaviour therapy for obsessive–compulsive disorder in young people with and without autism spectrum disorders: a case controlled study. Psychiatry Res 228:8–13CrossRefPubMed
31.
Russell AJ, Mataix-Cols D, Anson MAW, Murphy DGM (2009) Psychological treatment for obsessive–compulsive disorder in people with autism spectrum disorders–a pilot study. Psychother Psychosom 78:59–61CrossRefPubMed
32.
Russell AJ, Jassi A, Fullana MA, Mack H, Johnston K, Heyman I, Mataix-Cols D (2013) Cognitive behavior therapy for comorbid obsessive–compulsive disorder in high-functioning autism spectrum disorders: a randomized controlled trial. Depress Anxiety 30:697–708CrossRefPubMed
33.
Vause T, Neil N, Jaksic H, Jackiewicz G, Feldman M (2015) Preliminary randomized trial of function-based cognitive–behavioral therapy to treat obsessive compulsive behavior in children with autism spectrum disorder. Focus Autism Other Dev Disabl. doi:10.​1177/​1088357615588517​
34.
Scahill L, Riddle MA, McSwiggin-Hardin M, Ort SI, King RA, Goodman WK (1997) Children’s Yale-Brown obsessive compulsive scale: reliability and validity. J Am Acad Child Adolesc Psychiatry 36:844–852CrossRefPubMed
35.
AACAP (2012) Practice parameter for the assessment and treatment of children and adolescents with obsessive–compulsive disorder. J Am Acad Child Adolesc Psychiatry 51:98–113CrossRef
36.
Storch EA, Bagner DM, Geffken GR, Adkins JW, Murphy TK, Goodman WK (2007) Sequential cognitive–behavioral therapy for children with obsessive–compulsive disorder with an inadequate medication response: a case series of five patients. Depress Anxiety 24:375–381CrossRefPubMed
37.
Goodwin R, Koenen KC, Hellman F, Guardino M, Struening E (2002) Helpseeking and access to mental health treatment for obsessive–compulsive disorder. Acta Psychiatr Scand 106:143–149CrossRefPubMed
38.
Kessler RC, Avenevoli S, Costello EJ, Georgiades K, Green JG, Gruber MJ et al (2012) Prevalence, persistence, and sociodemographic correlates of DSM-IV disorders in the National Comorbidity Survey Replication Adolescent Supplement. Arch Gen Psychiatry 69:372–380CrossRefPubMed
39.
Kessler RC, Berglund P, Demler O, Jin R, Merikangas KR, Walters EE (2005) Lifetime prevalence and age-of-onset distributions of DSM-IV disorders in the National Comorbidity Survey Replication. Arch Gen Psychiatry 62:593–602CrossRefPubMed
40.
Oswald TM, Winter-Messiers MA, Gibson B, Schmidt AM, Herr CM, Solomon M (2016) Sex differences in internalizing problems during adolescence in autism spectrum disorder. J Autism Dev Disord 46:624–636CrossRefPubMed
41.
Rosa-Alcázar AI, Sánchez-Meca J, Rosa-Alcázar Á, Iniesta-Sepúlveda M, Olivares-Rodríguez J, Parada-Navas JL (2015) Psychological treatment of obsessive–compulsive disorder in children and adolescents: a meta-analysis. Span J Psychol 18:e20CrossRefPubMed
42.
Leckman JF, Sholomskas D, Thompson D, Belanger A, Weissman MM (1982) Best estimate of lifetime psychiatric diagnosis: a methodological study. Arch Gen Psychiatry 39:879CrossRefPubMed
43.
Iniesta-Sepúlveda M, Rosa-Alcázar AI, Rosa-Alcázar Á, Storch EA (2014) Evidence-based assessment in children and adolescents with obsessive–compulsive disorder. J Child Fam Stud 23:1455–1470CrossRef
44.
Storch EA, Murphy TK, Geffken GR, Soto O, Sajid M, Allen P et al (2004) Psychometric evaluation of the Children’s Yale–Brown obsessive–Compulsive Scale. Psychiatry Res 129:91–98CrossRefPubMed
45.
Wu MS, McGuire J, Arnold E, Lewin A, Murphy T, Storch EA (2014) Psychometric properties of the Children’s Yale-Brown Obsessive Compulsive Scale in Youth with Autism Spectrum Disorders and obsessive–Compulsive Symptoms. Child Psychiatry Hum Dev 45:201–211CrossRefPubMed
46.
Bird HR, Andrews H, Schwab-Stone M, Goodman S, Dulcan M, Richters J et al (1996) Global measures of impairment for epidemiologic and clinical use with children and adolescents. Int J Methods Psychiatr Res 6:295–307CrossRef
47.
Endicott J, Nee J, Yang R, Wohlberg C (2006) Pediatric quality of life enjoyment and satisfaction questionnaire (PQ-LES-Q): reliability and validity. J Am Acad Child Adolesc Psychiatry 45:401–407CrossRefPubMed
48.
Birmaher B, Khetarpal S, Brent D, Cully M, Balach L, Kaufman J, Neer SM (1997) The screen for child anxiety related emotional disorders (SCARED): scale construction and psychometric characteristics. J Am Acad Child Adolesc Psychiatry 36:545–553CrossRefPubMed
49.
Stern JA, Gadgil MS, Blakeley-Smith A, Reaven JA, Hepburn SL (2014) Psychometric properties of the SCARED in youth with autism spectrum disorder. Res Autism Spectr Disord 8:1225–1234CrossRefPubMedPubMedCentral
50.
Irwin DE, Stucky B, Langer MM, Thissen D, DeWitt EM, Lai JS et al (2010) An item response analysis of the pediatric PROMIS anxiety and depressive symptoms scales. Qual Life Res 19:595–607CrossRefPubMedPubMedCentral
51.
NIMH (1985) Rating scales and assessment instruments for use in pediatric psychopharmacology research. Psychopharmacol Bull 21:839–843
52.
Lewin AB, Piacentini J (2010) Evidence-based assessment of child obsessive compulsive disorder: recommendations for clinical practice and treatment research. Child Youth Care Forum 39:73–89CrossRefPubMedPubMedCentral
53.
Pituch KA, Green VA, Didden R, Lang R, O’Reilly MF, Lancioni GE, Sigafoos J (2011). Parent reported treatment priorities for children with autism spectrum disorders. Res Autism Spectr Disord 5:135–143CrossRef
54.
Storch EA, Lewin AB, De Nadai AS, Murphy TK (2010) Defining treatment response and remission in obsessive–compulsive disorder: a signal detection analysis of the Children’s Yale-Brown Obsessive Compulsive Scale. J Am Acad Child Adolesc Psychiatry 49:708–717PubMed
55.
Storch EA, Arnold EB, Lewin AB, Nadeau JM, Jones AM, De Nadai AS et al (2013) The effect of cognitive–behavioral therapy versus treatment as usual for anxiety in children with autism spectrum disorders: a randomized, controlled trial. J Am Acad Child Adolesc Psychiatry 52:132–142CrossRefPubMed
56.
Conelea CA, Freeman JB (2015) What do therapists and clients do during exposures for OCD? Introduction to the special issue on theory-based exposure process. J Obsessive Compuls Relat Disord 6:144–146CrossRef
57.
Taboas WR, McKay D, Whiteside SP, Storch EA (2015) Parental involvement in youth anxiety treatment: conceptual bases, controversies, and recommendations for intervention. J Anxiety Disord 30:16–18CrossRefPubMed
58.
Whiteside SP, McKay D, De Nadai AS, Tiede MS, Ale CM, Storch EA (2014) A baseline controlled examination of a 5-day intensive treatment for pediatric obsessive–compulsive disorder. Psychiatry Res 220:441–446CrossRefPubMed
59.
Storch EA, Lehmkuhl HD, Ricketts E, Geffken GR, Marien W, Murphy TK (2010) An open trial of intensive family based cognitive–behavioral therapy in youth with obsessive–compulsive disorder who are medication partial responders or nonresponders. J Clin Child Adolesc Psychol 39:260–268CrossRefPubMed
60.
Kerns CM, Kendall PC, Berry L, Souders MC, Franklin ME, Schultz RT et al (2014) Traditional and atypical presentations of anxiety in youth with autism spectrum disorder. J Autism Dev Disord 44:2851–2861CrossRefPubMedPubMedCentral
Metagegevens
Titel
An Initial Case Series of Intensive Cognitive–Behavioral Therapy for Obsessive–Compulsive Disorder in Adolescents with Autism Spectrum Disorder
Auteurs
Marina Iniesta-Sepúlveda
Joshua M. Nadeau
Amaya Ramos
Brian Kay
Bradley C. Riemann
Eric A. Storch
Publicatiedatum
07-04-2017
Uitgeverij
Springer US
Gepubliceerd in
Child Psychiatry & Human Development / Uitgave 1/2018
Print ISSN: 0009-398X
Elektronisch ISSN: 1573-3327
DOI
https://doi.org/10.1007/s10578-017-0724-1

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