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Predicting successful percutaneous coronary intervention in patients with chronic total occlusion: the incremental value of a novel morphological parameter assessed by computed tomography

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Abstract

To study the relationship between percutaneous coronary intervention (PCI) success and various morphological index evaluated by coronary computed tomography angiography (CCTA) in patients with coronary chronic total occlusion (CTO). 272 Consecutive patients with 281 CTO lesions diagnosed by CCTA and invasive coronary angiography were prospectively enrolled. The luminal attenuation of proximal segment of CTO lesions was measured. Other parameters, like lesion length, coronary calcium score, torturous course, stump morphology were also recorded. The attenuation of the proximal segment of CTO lesions was significantly higher in PCI failure group than it was in PCI success group (88 ± 19.7 vs. 70.2 ± 13, p < 0.001). Lesion length in PCI failure group was longer than those in PCI success group (20.4 ± 11.2 vs. 15.1 ± 5.85 mm, p < 0.001) and lesions in PCI failure group were more heavily calcified than lesions in PCI success group (Agatston score 61 vs. 5.7, p < 0.001). The attenuation of the proximal segment of CTO lesions, along with occlusion length and total coronary calcium score were significant independent predictors of PCI failure. The attenuation of the proximal segment of CTO lesions, along with occlusion length and total coronary calcium score as assessed by CCTA have predictive value for PCI outcomes.

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Acknowledgments

This study was Granted by the Ministry of Science and Technology of China (2007BAI05B02).

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There are no conflicts of interest.

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Authors and Affiliations

  1. Department of Radiology, State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, #167 Bei-Li-Shi Street, Beijing, 100037, China

    Yang Chen, Bin Lu, Zhi-hui Hou, Yang Gao, Fang-fang Yu, Wei-hua Yin & Zhi-qiang Wang

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  1. Yang Chen
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  2. Bin Lu
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  3. Zhi-hui Hou
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  4. Yang Gao
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  5. Fang-fang Yu
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  6. Wei-hua Yin
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  7. Zhi-qiang Wang
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Correspondence to Bin Lu.

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Chen, Y., Lu, B., Hou, Zh. et al. Predicting successful percutaneous coronary intervention in patients with chronic total occlusion: the incremental value of a novel morphological parameter assessed by computed tomography. Int J Cardiovasc Imaging 31, 1263–1269 (2015). https://doi.org/10.1007/s10554-015-0679-x

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  • DOI: https://doi.org/10.1007/s10554-015-0679-x

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