Skip to main content

Advertisement

SpringerLink
Log in

Effect of a multidiscipline mentor-based program, Be Resilient to Breast Cancer (BRBC), on female breast cancer survivors in mainland China—A randomized, controlled, theoretically-derived intervention trial

  • Clinical trial
  • Published:
Breast Cancer Research and Treatment Aims and scope Submit manuscript

Abstract

To reduce the risk of adjustment problems for breast cancer patients in mainland China, we examined the efficacy of a multidiscipline mentor-based program, Be Resilient to Breast Cancer (BRBC), delivered after breast surgery to (a) increase protective factors of social support, hope for the future, etc.; (b) decrease risk factors of Physical and Emotional Distress; and (c) increase outcomes of Resilience, Transcendence and Quality of Life (QOL). A multisite randomized controlled trial was conducted at 6 specialist cancer hospitals. 101 and 103 breast cancer patients were allocated to intervention group (IG) and control group (CG), respectively, and 112 general females (without breast cancer) were allocated to the norm group (NG). Participants completed measures that were related to latent variables derived from the Resilience Model for Breast Cancer (RM-BC) at baseline (T1), 2 months (T2), 6 months (T3), and 12 months (T4) after intervention. At T2, the IG reported significantly lower Depression (ES = 0.65,P = 0.0019) and Illness Uncertainty (ES = 0.57, P = 0.004), better Hope (ES = 0.81, P < 0.001) and QOL (ES = 0.60, P = 0.002) than did the CG. At T3, the IG reported significantly lower Anxiety (ES = 0.74, P < 0.001), better Social Support (ES = 0.51,P = 0.009), Transcendence (ES = 0.87, P < 0.001), and Resilience (ES = 0.83, P < 0.001) compared with the CG. At T4, the IG reported better Resilience though not significant (P = 0.085) and better Transcendence (P = 0.0243) than did the NG. The BRBC intervention improves the positive health outcomes and decreases the risk factors of illness-related distress of breast cancer patients during the high-risk cancer treatment.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3
Fig. 4
Fig. 5

Similar content being viewed by others

References

  1. Ferlay J, Bray F, Pisani P, Parkin DM (2004) Cancer incidence mortality and prevalence worldwide.GLOBOCAN,IARC cancer base no. 5, version 2.0. IARC Press, Lyon

    Google Scholar 

  2. Zhang ML, Huang ZZ, Zheng Y (2012) The chinese breast cancer incidence and mortality rates in 2008 and predictions for the future. Chin J Epidemiol 33(10):1049–1051

    Google Scholar 

  3. Kim SH, Lee R, Lee KS (2012) Symptoms and uncertainty in breast cancer survivors in korea: differences by treatment trajectory. J Clin Nurs 21:1014–1023

    Article  PubMed  Google Scholar 

  4. Stanton AL, Ganz PA, Kwan L, Meyerowitz BE, Bower JE, Krupnick JL, Belin TR (2005) Outcomes from the moving beyond cancer psychoeducational, randomized, controlled trial with breast cancer patients. J Clin Oncol 23:6009–6018

    Article  PubMed  Google Scholar 

  5. Allen JD, Savadatti S, Levy AG (2009) The transition from breast cancer ‘patient’ to ‘survivor’. Psycho Oncology. 18:71–78

    Article  PubMed  Google Scholar 

  6. Andersen BL, Yang HC, Farrar WB et al (2008) Psychologic intervention improves survival for breast cancer patients. Cancer 113:3450–3458

    Article  PubMed  PubMed Central  Google Scholar 

  7. Pedersen AE, Sawatzky JA, Hack TF (2010) The sequelae of anxiety in breast cancer: a human response to illness model. Oncol Nurs Forum 37:469–475

    Article  PubMed  Google Scholar 

  8. Gerber B, Freund M, Reimer T (2010) Recurrent breast cancer: treatment strategies for maintaining and prolonging good quality of life. Dtsch Arztebl Int 107:85–91

    PubMed  PubMed Central  Google Scholar 

  9. Haglund MEM, Nestadt PS, Cooper NS, Southwick SM, Charney DS (2007) Psy-chobiological mechanisms of resilience: relevance to prevention and treatment of stress-related psychopathology. Dev Psychopathol 19(3):889–920

    Article  CAS  PubMed  Google Scholar 

  10. Connor KM, Davidson JR (2003) Development of a new resilience scale: the connor-davidson resilience scale (cd-risc). Depress Anxiety 18:76–82

    Article  PubMed  Google Scholar 

  11. Kobasa SC (1979) Stressful life events, personality, and health: an inquiry into hardiness. J Pers Soc Psychol 37:1–11

    Article  CAS  PubMed  Google Scholar 

  12. Steinhardt M, Dolbier C (2008) Evaluation of a resilience intervention to enhance coping strategies and protective factors and decrease symptomatology. J Am Coll Health 56:445–453

    Article  PubMed  Google Scholar 

  13. Bradshaw BG, Richardson GE, Kumpfer K et al (2007) Determining the efficacy of a resiliency training approach in adults with type 2 diabetes. Diabetes Educ 33:650–659

    Article  PubMed  Google Scholar 

  14. Waite PJ, Richardson GE (2004) Determining the efficacy of resiliency training in the work site. J Allied Health 33:178–183

    PubMed  Google Scholar 

  15. Ruini C, Belaise C, Brombin C et al (2006) Well-being therapy in school settings: a pilot study. Psychother Psychosom 75:331–336

    Article  PubMed  Google Scholar 

  16. Scheier MF, Helgeson VS, Schulz R, Colvin S, Berga S, Bridges MW, Knapp J (2005) Interventions to enhance physical and psychological functioning among younger women who are ending nonhormonal adjuvant treatment for early-stage breast cancer. J Clin Oncol 23:4298–4311

    Article  PubMed  Google Scholar 

  17. Burgess C, Cornelius V, Sharon L, Graham J, Richards M, Ramirez A (2005) Depression and anxiety In women with early breast cancer: five-year observational cohort study. BMJ 330:702–705

    Article  PubMed  PubMed Central  Google Scholar 

  18. Hodgkinson K, Butow P, Hunt G, Pendlebury S, Hobbs K, Wain G (2007) Breast cancer survivors’ supportive care needs 2–10 years after diagnosis. Support Care Cancer 15:515–523

    Article  PubMed  Google Scholar 

  19. Loprinzi CE, Prasad K, Schroeder DR et al (2011) Stress management and resilience training (smart) program to decrease stress and enhance resilience among breast cancer survivors: a pilot randomized clinical trial. Clin Breast Cancer 11.6:364–368

    Article  Google Scholar 

  20. Fielding R, Hung J (1996) Preferences for information and involvement in decisions during cancer care among a hong kong chinese population. Psycho Oncol. 5:321–329

    Article  Google Scholar 

  21. Wong-Kim E, Sun A, Merighi JR, Chow EA (2005) Understanding quality-of-life issues in chinese women with breast cancer: a qualitative investigation. Cancer Control. 12(Suppl):S6–S12

    Google Scholar 

  22. Ashing-Giwa K, Padilla G, Tejero J, Kagawa-Singer M (2003) Understanding the breast cancer experience of asian american women. Psycho Oncol. 12:38–58

    Article  Google Scholar 

  23. Kim HS, Sherman DK, Taylor SE (2008) Culture and social support. Am Psychol 63:518–526

    Article  PubMed  Google Scholar 

  24. Lee S, Chen L, Ma GX, Fang CY (2012) What is lacking in patient-physician communication: perspectives from asian american breast cancer patients and oncologists. J Behav Health. 1:102–109

    Article  Google Scholar 

  25. Ye ZJ,Cai RQ,Luo DM.The exploratory evaluation of Resilience Model for Breast Cancer(RM-BC) among patients with breast cancer diagnosis.Chin J of Nurs,2015.(in press)

  26. Leung CM, Ho S, Kan CS et al (1993) Evaluation of the chinese version of the hospital anxiety and depression scale. a cross-cultural perspective. Inter J Psychosom 40:29–34

    CAS  Google Scholar 

  27. Kari BH, Turid A, Kirsten L et al (2015) Illness uncertainty in breast cancer patients: validation of the 5-item short form of the mishel uncertainty in illness scale. Eur J Oncol Nurs 19(2):113–119

    Article  Google Scholar 

  28. Sprangers MA, Cull A, Bjordal K et al (1993) The european organization for research and treatment of cancer. approach to quality of life assessment: guidelines for developing questionnaire modules.eortc study group on quality of life. Qual Life Res 2:287–295

    Article  CAS  PubMed  Google Scholar 

  29. Seeman TE, Berkman LF (1988) Structural characteristics of social networks and their relationship with social support in the elderly: who provides support. Soc Sci Med 26:737–749

    Article  CAS  PubMed  Google Scholar 

  30. Snyder CR, Harris C, Anderson JR et al (1991) The will and the ways: development and validation of an individual-differences measure of hope. J Personal Soc Psychol 60:570–585

    Article  CAS  Google Scholar 

  31. Campbell-Sills Laura, Murray BS (2007) Psychometric analysis and refinement of the connor-davidson resilience scale (cd-risc): validation of a 10-item measure of resilience. J Trauma Stress 20(6):1019–1028

    Article  PubMed  Google Scholar 

  32. Reed PG (1989) Mental health of older adults. West J Nurs Res 11(2):143–157

    Article  CAS  PubMed  Google Scholar 

  33. Faul F, Erdfelder E, Lang AG et al (2007) G*Power 3: a flexible sta-tistical power analysis program for the social, behavioral, and biomedical sciences. Behav Res Methods 39:175–191

    Article  PubMed  Google Scholar 

  34. Cohen J (1988) Statistical power analysis for the behavioral sciences, 2nd edn. Lawerence Erlbaum Associates, Inc., Hillsdale

    Google Scholar 

  35. Helgeson VS, Cohen S, Schulz R et al (1999) Education and peer discussion group interventions and adjustment to breast cancer. Arch Gen Psych. 56:340–347

    Article  CAS  Google Scholar 

  36. Goodwin PJ, Leszcz M, Ennis M et al (2001) The effect of group psychosocial support on survival in metastatic breast cancer. N Engl J Med 345:1719–1725

    Article  CAS  PubMed  Google Scholar 

  37. Rini C, Lawsin C, Austin J et al (2006) Peer mentoring and survivors’ stories for cancer patients: positive effects and some cautionary notes. J Clin Oncol 25:163–166

    Article  Google Scholar 

  38. Lee S, Chen L, Ma GX, Fang CY, Oh Y, Scully L (2013) Challenges and needs of chinese and korean american breast cancer survivors: in-depth interviews. North Am J Med Sci. 6:1–8

    Google Scholar 

  39. Lu Q, Zheng D, Young L, Kagawa-Singer M, Loh A (2012) A pilot study of expressive writing intervention among chinese-speaking breast cancer survivors. Health Psychol 31:548–551

    Article  PubMed  PubMed Central  Google Scholar 

  40. Lu Q, You J, Man J et al (2014) Evaluating a culturally tailored peer-mentoring and education pilot intervention among chinese breast cancer survivors using a mixed-methods approach. Oncol Nurs Forum No.6:629–637

    Article  Google Scholar 

Download references

Acknowledgments

The authors gratefully acknowledge the assistance of the patients with breast cancer who participated in this study. The contribution made by the hospitals and the university is also acknowledged.

Author contributions

The following authors or their immediate family members have indicated no financial interest. No conflict exists for drugs or devices used in a study if they are not being evaluated as part of the investigation. Research Funding: Zeng Jie Ye; Xiao Ming Quan Conception and design: Zeng Jie Ye; Mu Zi Liang; Hong Zhong Qiu; Xiao Ming Quan. Administrative support: Zeng Jie Ye; Xiao Ming Quan Provision of study materials or patients: Mu Zi Liang; Hong Zhong Qiu; Mei Ling Liu; Guang Yun Hu; Zeng Zeng; Yun Fei Zhu; Jing Jing Zhao. Collection and assembly of data: Mu Zi Liang; Hong Zhong Qiu; Mei Ling Liu; Guang Yun Hu; Zeng Zeng; Yun Fei Zhu; Jing Jing Zhao. Data analysis and interpretation: Zeng Jie Ye; Mu Zi Liang; Hong Zhong Qiu; Xiao Ming Quan. Manuscript writing: All authors Final approval of manuscript: All authors.

Author information

Author notes

    Authors and Affiliations

    1. College of Economics and Management, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong province, China

      Zeng Jie Ye & Hong Zhong Qiu

    2. The First Affiliated Hospital, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong province, China

      Zeng Jie Ye, Guang Yun Hu, Yun Fei Zhu & Zhen Zeng

    3. Guangzhou University of Chinese Medicine, Guangzhou, Guangdong province, China

      Mu Zi Liang

    4. Sun Yat-sen University Cancer Center, Guangzhou, Guangdong province, China

      Mei Ling Liu

    5. The Second Affiliated Hospital, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong province, China

      Jing Jing Zhao

    6. Nursing Department of The First Affiliated Hospital, Guangzhou University of Chinese Medicine, Guangzhou, Guangdong province, China

      Xiao Ming Quan

    Authors
    1. Zeng Jie Ye
      View author publications

      You can also search for this author in PubMed Google Scholar

    2. Mu Zi Liang
      View author publications

      You can also search for this author in PubMed Google Scholar

    3. Hong Zhong Qiu
      View author publications

      You can also search for this author in PubMed Google Scholar

    4. Mei Ling Liu
      View author publications

      You can also search for this author in PubMed Google Scholar

    5. Guang Yun Hu
      View author publications

      You can also search for this author in PubMed Google Scholar

    6. Yun Fei Zhu
      View author publications

      You can also search for this author in PubMed Google Scholar

    7. Zhen Zeng
      View author publications

      You can also search for this author in PubMed Google Scholar

    8. Jing Jing Zhao
      View author publications

      You can also search for this author in PubMed Google Scholar

    9. Xiao Ming Quan
      View author publications

      You can also search for this author in PubMed Google Scholar

    Corresponding authors

    Correspondence to Zeng Jie Ye or Xiao Ming Quan.

    Ethics declarations

    Conflict of interest

    The authors have no financial disclosures or conflicts of interest to make.

    Additional information

    Zeng Jie Ye, Mu Zi Liang, and Hong Zhong Qiu have contributed equally to this work and should be considered co-first authors.

    Rights and permissions

    Reprints and permissions

    About this article

    Check for updates. Verify currency and authenticity via CrossMark

    Cite this article

    Ye, Z.J., Liang, M.Z., Qiu, H.Z. et al. Effect of a multidiscipline mentor-based program, Be Resilient to Breast Cancer (BRBC), on female breast cancer survivors in mainland China—A randomized, controlled, theoretically-derived intervention trial. Breast Cancer Res Treat 158, 509–522 (2016). https://doi.org/10.1007/s10549-016-3881-1

    Download citation

    • Received:

    • Accepted:

    • Published:

    • Issue Date:

    • DOI: https://doi.org/10.1007/s10549-016-3881-1

    Keywords

    Search

    Navigation