Abstract
Latino sexual minority men (SMM) have high HIV incidence rates but report low pre-exposure prophylaxis (PrEP) use. Medical mistrust predicts lower medical care use and could contribute to decreased PrEP engagement. This study examines how medical mistrust relates to the PrEP cascade among 151 Latino SMM aged 18–29. Logistic regressions were employed with medical mistrust predicting PrEP awareness, willingness, current use, and adherence. Greater medical mistrust was associated with decreased odds of all outcomes and may represent a barrier to PrEP engagement for Latino SMM. Further research should explore whether reducing medical mistrust among Latino SMM could increase PrEP engagement.
Resumen
Los hombres de sexualidad minoría latinos (HSML) tienen altas tasas de VIH, pero reportan bajo uso de profilaxis preexposición (PrEP). La desconfianza médica (DM) predice menor uso de atención médica y podría contribuir a menor uso de PrEP. Este estudio examina cómo la DM se relaciona con la cascada de PrEP entre 151 HSML. Se realizaron regresiones logísticas con DM prediciendo conocimiento, disposición, uso y adherencia de PrEP. Alta DM se asoció con menos probabilidad de todos los resultados y puede representar una barrera hacia PrEP. Futuras investigaciones deberían explorar si reduciendo la DM entre HSML aumenta compromiso con PrEP.
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References
Centers for Disease Control and Prevention (CDC). HIV and gay and bisexual men. Centers for Disease Control and Prevention. https://www.cdc.gov/hiv/group/msm/index.html. Accessed 5 Aug 2019.
Pulsipher CA, Montoya JA, Plant A, et al. Addressing PrEP disparities among young gay and bisexual men in California. Los Angeles: California HIV/AIDS Research Program; 2016.
Parsons JT, Rendina HJ, Lassiter JM, et al. Uptake of HIV pre-exposure prophylaxis (PrEP) in a national cohort of gay and bisexual men in the United States: the motivational PrEP cascade. J Acquir Immune Defic Syndr Hum Retrovirol (1999). 2017;74(3):285.
Blashill AJ, Brady JP, Rooney BM, Rodriguez-Diaz CE, Horvath K, Blumenthal J, Morris S, Moore DJ, Safren SA. Syndemics and the PrEP cascade: results from a sample of young Latino MSM. Arch Sex Behav. 2019;49:125.
Sewell AA. Disaggregating ethnoracial disparities in physician trust. Soc Sci Res. 2015;1(54):1–20.
Eaton LA, Driffin DD, Smith H, et al. Psychosocial factors related to willingness to use pre-exposure prophylaxis for HIV prevention among Black men who have sex with men attending a community event. Sex Health. 2014;11(3):244–51.
Holloway IW, Tan D, Gildner JL, et al. Facilitators and barriers to pre-exposure prophylaxis willingness among young men who have sex with men who use geosocial networking applications in California. AIDS Patient Care STDs. 2017;31(12):517–27.
Gwadz M, Applegate E, Cleland C, et al. HIV-infected individuals who delay, decline, or discontinue antiretroviral therapy: comparing clinic-and peer-recruited cohorts. Front Public Health. 2014;16(2):81.
Thompson HS, Valdimarsdottir HB, Winkel G, Jandorf L, Redd W. The Group-Based Medical Mistrust Scale: psychometric properties and association with breast cancer screening. Prev Med. 2004;38(2):209–18.
Wheldon CW, Kolar SK, Hernandez ND, Daley EM. Factorial invariance and convergent validity of the group-based medical mistrust scale across gender and ethnoracial identity. J Health Care Poor Underserved. 2017;28(1):88–99.
Galvan F, Bogart H, Klein L, Wagner M, Chen D. Medical mistrust as a key mediator in the association between perceived discrimination and adherence to antiretroviral therapy among HIV-positive Latino men. J Behav Med. 2017;40(5):784–93.
Bogart LM, Mutchler MG, McDavitt B, et al. A randomized controlled trial of rise, a community-based culturally congruent adherence intervention for black Americans living with HIV. Ann Behav Med. 2017;51(6):868–78.
Acknowledgements
David Rivera’s work on this project was supported by the National Institutes of Health award number 5 R25 GM058906.
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All authors contributed to study design and conception. AB performed data collection and DK, MG, and AB contributed to data analysis. DK, DR, and MG wrote the first draft of the manuscript, and all authors contributed to manuscript edits. All authors read and approved the final manuscript.
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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee (San Diego State University Institutional Review Board) and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. This article does not contain any studies with animals performed by any of the authors.
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Kimball, D., Rivera, D., Gonzales, M. et al. Medical Mistrust and the PrEP Cascade Among Latino Sexual Minority Men. AIDS Behav 24, 3456–3461 (2020). https://doi.org/10.1007/s10461-020-02916-z
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DOI: https://doi.org/10.1007/s10461-020-02916-z