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An Information–Motivation–Behavioral Skills Model of PrEP Uptake

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Abstract

Despite documented effectiveness of pre-exposure prophylaxis (PrEP), PrEP uptake remains low among at-risk populations. The 2015 CDC report estimates that about 1.2 million people in the US have indications for PrEP. However, only 49,158 or 4% of the targeted population are currently using PrEP. Efforts to optimize uptake of PrEP may be facilitated by the development of a comprehensive theoretical framework which can be used to understand reasons for poor uptake and to develop interventions to maximize PrEP uptake and adherence. This article reviews research on correlates of PrEP uptake and presents findings organized within an Information-Motivation-Behavioral Skills (IMB) model framework. In the context of PrEP uptake, the IMB model asserts that to the extent that at-risk groups are well-informed about PrEP, motivated to act on their knowledge, and have necessary behavioral skills to seek out and initiate PrEP regimen, they will successfully overcome obstacles to initiate and adhere to PrEP. The article proposes an adaptation the IMB model for PrEP uptake, provides empirical support for the adapted IMB model extracted from related research, and discusses its application in PrEP uptake interventions.

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Funding

Financial support for this study was provided in part by the National Institute on Drug Abuse (K24 DA017072, Altice) and the National Institute of Arthritis and Musculoskeletal and Skin Diseases (AR060231-05, Fraenkel). The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health. The funding agreement ensured the authors’ independence in designing the study, interpreting the data, writing, and publishing the report.

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  1. Loma Linda University School of Public Health, Sanitarium Dr., Loma Linda, CA, 92354, USA

    Alex Dubov

  2. Department of Medicine and Public Health, Section of Infectious Diseases, AIDS Program, Yale University School of Medicine, 135 College Street, Suite 323, New Haven, CT, 06510-2283, USA

    Frederick L. Altice

  3. Department of Medicine, Section of Rheumatology, Yale University School of Medicine, PO Box 208031, 300 Cedar Street, TAC Bldg., New Haven, CT, 06520-8031, USA

    Liana Fraenkel

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Dubov, A., Altice, F.L. & Fraenkel, L. An Information–Motivation–Behavioral Skills Model of PrEP Uptake. AIDS Behav 22, 3603–3616 (2018). https://doi.org/10.1007/s10461-018-2095-4

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