Skip to main content

Advertisement

SpringerLink
Log in

Mapping of head and neck cancer patient concerns inventory scores on to Euroqol-Five Dimensions-Five Levels (EQ-5D-5L) health utility scores

  • Original Paper
  • Published:
The European Journal of Health Economics Aims and scope Submit manuscript

Abstract

Background

The purpose of this paper is to map the number of concerns on the dimensions in Head and Neck Patient Concerns Inventory (PCI) on to the health utility (HU) index scores on Euroqol-Five Dimensions-Five levels {EQ-5D-5L) .

Methods

This is a cross-sectional survey conducted in patients who have completed their treatment. Four candidate models were considered, three based on ordinary least squares regression (OLS) and one two-parts model.

Results

A reduced OLS model based on ‘Physical and functional’, ‘Treatment-related’, and ‘Psychological, emotional and spiritual well-being’ domains was found best on the estimation sample. This was validated externally on a separate sample.

Conclusions

This is the first study that mapped a non-QOL tool to generate HU scores on EQ-5D-5L. The proposed mapping algorithm can estimate the cost–utility in economic evaluation studies when HU scores are not directly available. The algorithm will be best suited for studies in low-middle income countries.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2

Similar content being viewed by others

References

  1. Muzaffar, J., Bari, S., Kirtane, K., Chung, C.H.: Recent advances and future directions in clinical management of head and neck squamous cell carcinoma. Cancers (Basel) 13, 338 (2021). https://doi.org/10.3390/cancers13020338

    Article  CAS  Google Scholar 

  2. Dandekar, M., Tuljapurkar, V., Dhar, H., Panwar, A., DCruz, A.K.: Head and neck cancers in India. J. Surg. Oncol. 115, 555–563 (2017). https://doi.org/10.1002/jso.24545

    Article  PubMed  Google Scholar 

  3. Tuljapurkar, V., Dhar, H., Mishra, A., Chakraborti, S., Chaturvedi, P., Pai, P.S.: The Indian scenario of head and neck oncology—challenging the dogmas. South Asian J. Cancer 5, 105–110 (2016). https://doi.org/10.4103/2278-330X.187573

    Article  PubMed  PubMed Central  Google Scholar 

  4. Caulley, L., Rodin, D., Kilty, S., Randolph, G., Hunink, M.G., Shin, J.J.: Evidence-based medicine in otolaryngology part 10: cost-effectiveness analyses in otolaryngology. Otolaryngol. Head Neck Surg. 161, 375–387 (2019)

    Article  Google Scholar 

  5. Caulley, L., Hunink, M.G., Kilty, S., et al.: Evidence-based medicine in otolaryngology part 9: valuing health outcomes. Otolaryngol. Head Neck Surg. 160, 11–21 (2019)

    Article  Google Scholar 

  6. Brazier, J.E., Yang, Y., Tsuchiya, A., Rowen, D.L.: A review of studies mapping (or cross walking) non-preference based measures of health to generic preference-based measures. Eur. J. Health Econ. 11, 215–225 (2010)

    Article  Google Scholar 

  7. Rogers, S.N., El-Sheikha, J., Lowe, D.: The development of a Patients Concerns Inventory (PCI) to help reveal patients concerns in the head and neck clinic. Oral Oncol. 45, 555–561 (2009)

    Article  CAS  Google Scholar 

  8. Rogers, S.N., Allmark, C., Bekiroglu, F., et al.: Improving quality of life through the routine use of the patient concerns inventory for head and neck cancer patients: main results of a cluster preference randomised controlled trial. Eur. Arch. Otorhinolaryngol. 278, 1–15 (2020)

    Article  Google Scholar 

  9. Rogers, S.N., Lowe, D., Yueh, B., Weymuller, E.A.: The physical function and social-emotional function subscales of the University of Washington quality of life questionnaire (UW-QOL). Arch. Otolaryngol. Head Neck Surg. 136, 352–357 (2010)

    Article  Google Scholar 

  10. Petrou, S., Rivero-Arias, O., Dakin, H., et al.: Preferred reporting items for studies mapping onto preference-based outcome measures: the MAPS statement. J. Med. Econ. 18, 851–857 (2015)

    Article  Google Scholar 

  11. Rogers, S.N., Alvear, A., Anesi, A., et al.: Variations in concerns reported on the patient concerns inventory in patients with head and neck cancer from different health settings across the world. Head Neck 42, 498–512 (2020)

    Article  Google Scholar 

  12. van Hout, B., Janssen, M.F., Feng, Y.S., et al.: Interim scoring for the EQ-5D-5L: mapping the EQ-5D-5L to EQ-5D-3L value sets. Value Health 15, 708–715 (2012)

    Article  Google Scholar 

  13. Prinja, S., Downey, L.E., Gauba, V.K., et al.: Health technology assessment for policy making in India: current scenario and way forward. Pharmacoecon. Open 2, 1–3 (2018)

    Article  Google Scholar 

  14. Department of Health Research: Health technology assessment in India: process manual. Department of Health Research, Ministry of Health and Family Welfare, Government of India, New Delhi (2018)

    Google Scholar 

  15. Wailoo, A.J., Hernandez-Alava, M., Manca, A., et al.: Mapping to estimate health-state utility from non–preference-based outcome measures: an ISPOR good practices for outcomes research task force report. Value Health 20, 18–27 (2017)

    Article  Google Scholar 

  16. Acaster, S., Pinder, B., Mukuria, C., Copans, A.: Mapping the EQ-5D index from the cystic fibrosis questionnaire-revised using multiple modelling approaches. Health Qual. Life Outcomes 13, 33 (2015)

    Article  Google Scholar 

  17. Cohen, J.: Statistical power analysis for the behavioural sciences, pp. 531–542. Lawrence Erlbaum Associates, Hillsdale (1988)

    Google Scholar 

  18. Miller, N., Rogers, S.N.: A review of question prompt lists used in the oncology setting with comparison to the patient concerns inventory. Eur. J. Cancer Care (Engl) (2018). https://doi.org/10.1111/ecc.12489

    Article  Google Scholar 

  19. Shunmugasundaram, C., Rutherford, C., Butow, P.N., Sundaresan, P., Dhillon, H.M.: Content comparison of unmet needs self- report measures used in patients with head and neck cancer: a systematic review. Psychooncology 28, 2295–2306 (2019)

    Article  Google Scholar 

  20. Stephens, R.F., Noel, C.W., Su, J.S., et al.: Mapping the University of Washington Quality of life questionnaire onto EQ-5D and HUI-3 indices in patients with head and neck cancer. Head Neck 42, 513–521 (2020)

    Article  Google Scholar 

  21. Noel, C.W., Stephens, R.F., Su, J.S., et al.: Mapping the EORTC QLQ-C30 and QLQ-H&N35, onto EQ-5D-5L and HUI-3 indices in patients with head and neck cancer. Head Neck 42, 2277–2286 (2020)

    Article  Google Scholar 

  22. Rogers, S., Miller, R., Ali, K., Minhas, A., Williams, H., Lowe, D.: Patients’ perceived health status following primary surgery for oral and oropharyngeal cancer. Int. J. Oral Maxillofac. Surg. 35, 913–919 (2006)

    Article  CAS  Google Scholar 

  23. Chan, K.K., Willan, A.R., Gupta, M., Pullenayegum, E.: Underestimation of uncertainties in health utilities derived from mapping algorithms involving health-related quality-of-life measures: statistical explanations and potential remedies. Med. Decis. Making 34, 863–872 (2014)

    Article  Google Scholar 

Download references

Funding

None.

Author information

Authors and Affiliations

  1. Department of Head and Neck Surgery and Oncology, Amrita Institute of Medical Sciences and Research Center, Amrita Vishwa Vidyapeetham, Kochi, 682041, Kerala, India

    Krishnakumar Thankappan, Tejal Patel, Krishna Kollamparambil Ajithkumar, Deepak Balasubramanian & Subramania Iyer

  2. Division of Paediatrics and Public Health Research, Amrita Institute of Medical Sciences, Amrita Vishwa Vidyapeetham, Kochi, Kerala, India

    Manu Raj

  3. RTI International, Waltham, MA, USA

    Sujha Subramanian

Authors
  1. Krishnakumar Thankappan
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Tejal Patel
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. Krishna Kollamparambil Ajithkumar
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. Deepak Balasubramanian
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. Manu Raj
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. Sujha Subramanian
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. Subramania Iyer
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Krishnakumar Thankappan.

Ethics declarations

Conflict of interest

None.

Ethical approval

The study got approval from the institutional review board, Amrita Institute of Medical Sciences, Kochi, India.

Consent to participate

Informed consent was taken from the patients.

Additional information

Publisher's Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Thankappan, K., Patel, T., Ajithkumar, K.K. et al. Mapping of head and neck cancer patient concerns inventory scores on to Euroqol-Five Dimensions-Five Levels (EQ-5D-5L) health utility scores. Eur J Health Econ 23, 225–235 (2022). https://doi.org/10.1007/s10198-021-01369-y

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10198-021-01369-y

Keywords

JEL Classification

Search

Navigation