Skip to main content
Log in

Healthy donor effect and satisfaction with health

The role of selection effects related to blood donation behavior

  • Original Paper
  • Published:
The European Journal of Health Economics Aims and scope Submit manuscript

Abstract

The objective of this paper is to quantify selection effects related to blood donation behavior and their impact on donors’ perceived health status. We rely on data from the 2009 and 2010 survey waves of the German socio-economic panel (N = 12,000), including information on health-related, demographic and psychographic factors as well as monetary donation behavior and volunteer work. We propose a propensity score matching approach to control for the healthy donor effect related to the health requirements for active blood donations. We estimate two separate models and quantify selection biases between (1) active and inactive blood donors and (2) active donors and non-donors. Our results reveal that active donors are more satisfied with their health status; after controlling for selection effects, however, the differences become non-significant, revealing selection biases of up to 82 % compared with non-donors. These differences also exist between active and inactive donors, but the differences are less distinct. Our methodological approach reveals and quantifies selection biases attributable to the healthy donor effect. These biases are substantial enough to lead to erroneous statistical artifacts, implying that researchers should rigorously control for selection biases when comparing the health outcomes of different blood donor groups.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Similar content being viewed by others

Notes

  1. http://www.redcrossblood.org/donating-blood/eligibility-requirements. Accessed August 2014.

  2. http://www.americanredcrossblood.org/faq.html. Accessed on 10 June 2014.

  3. For a mathematical description of PSM see Mithas and Krishnan [29].

  4. Detailed documentation for the SOEP data is open to the public via the project’s homepage; (www.diw.de/soep).

  5. See e.g., http://www.blutspende-ost.de/infos-zur-blutspende/spenderinformationen/blutspender-gesucht.php.

  6. See http://www.diw.de/en/diw_02.c.222729.en/questionnaires.htmlfor the complete questionnaires.

  7. The positive effect of drinking more alcohol on the probability of being an active donor as compared to being a non-donor is somehow inconsistent with the healthy donor effect. While we can only speculate regarding the causes for this effect, we assume that the effect is inverted U-shaped; i.e., that very high levels of drinking alcohol influence the probability of being an active blood donor negatively. A robustness check shows indeed that the squared effect for drinking alcohol is significantly negative (p < 0.05) in the model comparing active donors and non-donors (and not significant in the model comparing active and inactive donors). The squared effect does not influence the PSM results and the estimates can be provided by the authors upon request.

References

  1. Glynn, S.A., Kleinman, S.H., Schreiber, G.B., Zuck, T., Mc Combs, S., Bethel, J., Garratty, G., Williams, A.E.: Motivations to donate blood: demographic comparisons. Transfusion 42(2), 216–225 (2002)

    Article  PubMed  Google Scholar 

  2. World Health Organization (2013). http://www.who.int/mediacentre/factsheets/fs279/en/. Accessed 22 Aug 2013

  3. Ascherio, A., Rimm, E.B., Giovannucci, E., Willett, W.C., Stampfer, M.J.: Blood donations and risk of coronary heart disease in men. Circulation 103, 52–57 (2001)

    Article  CAS  PubMed  Google Scholar 

  4. Salonen, J.T., Tuomainen, T.P., Salonen, R., Lakka, T.A., Nyyssonen, K.: Donation of blood is associated with reduced risk of myocardial infarction. The Kuopio Ischaemic Heart Disease Risk Factor Study. Am J Epidemiol 148, 445–451 (1998)

    Article  CAS  PubMed  Google Scholar 

  5. Zacharski, L.R., Chow, B.K., Howes, P.S., Shamayeva, G., Baron, J.A., Dalman, R.L., Malenka, D.J., Ozaki, C.K., Lavori, P.W.: Decreased cancer risk after iron reduction in patients with peripheral arterial disease: results from a randomized trial. J Natl Cancer Inst 100(14), 996–1002 (2008)

    Article  CAS  PubMed  Google Scholar 

  6. Atsma, F., de Vegt, F.: The healthy donor effect: a matter of selection bias and confounding. Transfusion 51(9), 1883–1885 (2011)

    Article  PubMed  Google Scholar 

  7. Atsma, F., Veldhuizen, I., Verbeek, A., de Kort, W., de Vegt, F.: Healthy donor effect: its magnitude in health research among blood donors. Transfusion 51(8), 1820–1828 (2011)

    Article  PubMed  Google Scholar 

  8. Benyamini, Y., Idler, E.: Community studies reporting association between self-rated health and mortality: additional studies 1995 to 1998. Res Aging 21(3), 392–401 (1999)

    Article  Google Scholar 

  9. DeSalvo, K., Bloser, N., Reynolds, K., He, J., Muntner, P.: Mortality prediction with a single general self-rated health question: a meta-analysis. J Gen Intern Med 21(3), 267–275 (2006)

    Article  PubMed Central  PubMed  Google Scholar 

  10. Mossey, J.N., Shapiro, E.: Self-rated health: a predictor of mortality among the elderly. Am J Public Health 72(8), 800–808 (1982)

    Article  PubMed Central  CAS  PubMed  Google Scholar 

  11. Idler, E., Benyamini, Y.: Self-rated health and mortality: a review of twenty-seven community studies. J Health Soc Behav 38(1), 21–37 (1997)

    Article  CAS  PubMed  Google Scholar 

  12. Nielsen, S., Brit, A., Siersma, V., Hiort, C., et al.: Self-rated general health among 40-year-old Danes and its association with all-cause mortality at 10-, 20-, and 29 years’ follow-up. Scand J Public Health 36(1), 3–11 (2008)

    Article  PubMed  Google Scholar 

  13. Jylhä, M., Volpato, S., Guralnik, J.: Self-rated health showed a graded association with frequently used biomarkers in a large population sample. J Clin Epidemiol 59(5), 465–471 (2006)

    Article  PubMed  Google Scholar 

  14. Banks, J., Crossley, T., Goshev, S.: Looking for private information in self-assessed health. In: HEDG Working Paper. University of York (2007)

  15. Bond, J., Dickinson, H., Matthews, F., Jagger, C., Brayne, C.: Self-rated health status as a predictor of death, functional and cognitive impairment: a longitudinal cohort study. Eur J Ageing 3(4), 193–206 (2006)

    Article  Google Scholar 

  16. Edgren, G., Reilly, M., Hjalgrim, H., Tran, T.N., Rostgaard, K., Adami, J., Titlestad, K., Shanwell, A., Melbye, M., Nyren, O.: Donation frequency, iron loss, and risk of cancer among blood donors. J Natl Cancer Inst 100, 572–579 (2008)

    Article  PubMed  Google Scholar 

  17. Burnett, J.J.: Psychological and demographic characteristics of blood donors. J Consum Res 8(1), 62–66 (1981)

    Article  Google Scholar 

  18. Veldhuizen, I.J.T., Doggen, C.J.M., Atsma, F., De Kort, W.L.A.M.: Donor profiles: demographic factors and their influence on the donor career. Vox Sang 97(2), 129–138 (2009)

    Article  CAS  PubMed  Google Scholar 

  19. Nguyen, D.D., DeVita, D.A., Hirschler, N.V., Murphy, E.L.: Blood donor satisfaction and intention of future donation. Transfusion 48(4), 742–748 (2008)

    Article  PubMed Central  PubMed  Google Scholar 

  20. Condie, S., Maxwell, N.: Comparative demographic profiles: voluntary and paid blood donors. Transfusion 10(2), 84–88 (1970)

    Article  CAS  PubMed  Google Scholar 

  21. Ibrahim, N.A., Mobley, M.F.: Recruitment and retention of blood donors: a strategic linkage approach. Health Care Manage Rev 18(3), 67–73 (1993)

    Article  CAS  PubMed  Google Scholar 

  22. Ringwald, J., Zimmermann, R., Eckstein, R.: Keys to open the door for blood donors to return. Transfus Med Rev 24(4), 295–304 (2010)

    Article  PubMed  Google Scholar 

  23. Rubin, D., Thomas, N.: Matching using estimated propensity scores: relating theory to practice. Biometrics 52(1), 249–264 (1966)

    Article  Google Scholar 

  24. Caliendo, M., Scheel-Copeinig, S.: Some practical guidance for the implementation of propensity score matching. J Econ Surv 22(1), 31–72 (2008)

    Article  Google Scholar 

  25. Roy, A.: Some thoughts on the distribution of earnings. Oxf Econ Pap 3(2), 135–145 (1951)

    Google Scholar 

  26. Imbens, G.W.: Nonparametric estimation of average treatment effects under exogeneity: a review. Rev Econ Stat 86(1), 4–29 (2004)

    Article  Google Scholar 

  27. Mithas, S., Krishnan, M.S.: From association to causation via a potential outcomes approach. Inf Syst Res 20(2), 295–313 (2009)

    Article  Google Scholar 

  28. Heckman, J.J., Ichimura, H., Todd, P.: Matching as an econometric evaluation estimator. Rev Econ Stud 65(2), 261–294 (1998)

    Article  Google Scholar 

  29. Krupp, H.J.: Das Sozio-oekonomische Panel (SOEP)–Genese und Implementation. In: SOEP-papers on multidisciplinary panel data research, pp. 2–16. DIW, Berlin (2007)

  30. Lee, L., Piliavin, J.A., Call, V.R.A.: Giving time, money, and blood: similarities and differences. Soc Psychol Q 62(3), 276–290 (1999)

    Article  Google Scholar 

  31. Andaleeb, S.S., Basu, A.K.: Explaining blood donation: the trust factor. J Health Care Mark 15(1), 42–48 (1995)

    CAS  PubMed  Google Scholar 

  32. Bekkers, R.: Traditional and health-related philanthropy: the role of resources and personality. Soc Psychol Q 69(4), 349–366 (2006)

    Article  Google Scholar 

  33. Boulware, L.E., Ratner, L.E., Ness, P.M., Cooper, L.A., Campbell-Lee, S., LaVeist, T.A., Powe, N.R.: The contribution of sociodemographic, medical, and attitudinal factors to blood donation among the general public. Transfusion 42(6), 669–678 (2002)

    Article  CAS  PubMed  Google Scholar 

  34. Hofmann, A., Browne, M.: One-sided commitment in dynamic insurance contracts: the market for private health insurance in Germany. J Risk Uncertain 46(1), 81–112 (2013)

    Article  Google Scholar 

  35. Burnett, J.J.: Examining the profiles of the donor and nondonor through a multiple discriminant approach. Transfusion 22(2), 138–142 (1982)

    Article  CAS  PubMed  Google Scholar 

  36. Newman, K., Pyne, T.: Service quality and blood donors–a marketing perspective. J Mark Managt 13(6), 579–599 (1997)

    Article  Google Scholar 

  37. Nonis, S.A., Ford, C.W., Logan, L., Hudson, G.: College student’s blood donation behavior: relationships to demographics, perceived risk, and incentives. Health Mark. Q 13(4), 33–46 (1996)

    Article  CAS  PubMed  Google Scholar 

  38. Tscheulin, D.K., Lindenmeier, J.: The willingness to donate blood: an empirical analysis of socio-demographic and motivation-related determinants. Health Serv Manage Res: an official journal of the Association of University Programs in Health Administration/HSMC, AUPHA 18(3), 165–174 (2005)

    Article  Google Scholar 

  39. Duboz, P., Cuneo, B.: How barriers to blood donation differ between lapsed donors and non-donors in France. Transfus Med 20(4), 227–236 (2010)

    Article  CAS  PubMed  Google Scholar 

  40. Oswalt, R.M., Hoff, T.E.: The motivations of blood donors and nondonors: a community survey. Transfusion 15(1), 68–72 (1975)

    Article  CAS  PubMed  Google Scholar 

  41. Burnett, J.J., Leigh, J.H.: Distinguishing characteristics of blood donor segments defined in terms of donation frequency. J Health Care Mark 6(2), 38–48 (1986)

    CAS  PubMed  Google Scholar 

  42. Silverman, B.W.: Density estimation for statistics and data analysis. Chapman & Hall, London (1986)

    Book  Google Scholar 

  43. Priller, E., Schupp, J.: Soziale und ökonomische Merkmale von Geld- und Blutspendern in Deutschland. DIW Wochenbericht 78(29), 3–10 (2011)

    Google Scholar 

  44. Shehu, E., Langmaack, A.-C., Felchle, E. and Clement, M.: Profiling donors of blood, money and time: a simultaneous comparison of the German population, Nonprofit Management & Leadership, forthcoming

  45. Sianesi, B.: An evaluation of Swedish system of active labour market programmes in the 1990s. Rev Econ Stat 86(1), 133–155 (2004)

    Article  Google Scholar 

  46. Black, D., Smith, J.: How robust is the evidence on the effects of college quality? Evidence from matching. J Econom 121, 99–124 (2004)

    Article  Google Scholar 

  47. Lechner, M.: Some practical issues in the evaluation of heterogeneous labour market programmes by matching methods. J R Stat Soc A 165, 59–82 (2002)

    Article  Google Scholar 

  48. Rosenbaum, P.R.: Observational studies. Springer, New York (2002)

    Book  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Edlira Shehu.

Electronic supplementary material

Below is the link to the electronic supplementary material.

Supplementary material 1 (DOCX 394 kb)

Appendices

Appendix 1

See Table 4.

Table 4 Operationalization of variables

Appendix 2

The SOEP survey contained self-stated information related to hospital admissions of the respondents. Specifically, respondents were asked to state the number of nights spent in hospitals assessed by the open question “How many nights altogether did you spend in hospital last year?” We used the variable “number of nights spent in hospitals” as an alternative outcome of our PSM models for investigating the robustness of our results (Table 5).

Table 5 Comparison of the hospitalized nights as indication of the health status

The results are consistent with those displayed in Table 3 (see Table 5). We find significant differences between active and inactive donors and between active donors and non-donors regarding the number of nights spent in hospitals before matching. Active donors spent significantly fewer nights in hospitals, indicating a better health status. However, after considering the selection biases related to the healthy donor effect, the differences become non-significant (see Table 5).

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Shehu, E., Hofmann, A., Clement, M. et al. Healthy donor effect and satisfaction with health. Eur J Health Econ 16, 733–745 (2015). https://doi.org/10.1007/s10198-014-0625-1

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s10198-014-0625-1

Keywords

JEL Classification

Navigation