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The effects of laser irradiation on Trichophyton rubrum growth

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Abstract

The effects of various laser wavelengths and fluences on the fungal isolate, Trichophyton rubrum, were examined in vitro. Standard-size isolates of T. rubrum were irradiated by using various laser systems. Colony areas were compared for growth inhibition on days 1, 3, and 6 after laser irradiation. Statistically significant growth inhibition of T. rubrum was detected in colonies treated with the 1,064-nm Q-switched Nd:YAG laser at 4 and 8 J/cm2 and 532-nm Q-switched Nd:YAG laser at 8 J/cm2. Q-switched Nd:YAG laser at 532- and 1,064-nm wavelengths produced significant inhibitory effect upon the fungal isolate T. rubrum in this in vitro study. However, more in vitro and in vivo studies are necessary to investigate if lasers would have a potential use in the treatment of fungal infections of skin and its adnexa.

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Authors and Affiliations

  1. Department of Otolaryngology-Head and Neck Surgery, University of Arkansas for Medical Sciences, 4301 West Markham, Slot 543, Little Rock, AR, 72205, USA

    Emre Vural & Gal Shafirstein

  2. Division of Otolaryngology-Head and Neck Surgery, John McClellan VA Hospital, Little Rock, AR, USA

    Emre Vural

  3. Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, AR, USA

    Harry L. Winfield

  4. Ecology, Evolutionary Biology & Behavior Program, Department of Zoology, Michigan State University, East Lansing, MI, USA

    Alexander W. Shingleton

  5. Department of Dermatology, University of Arkansas for Medical Sciences, Little Rock, AR, USA

    Thomas D. Horn

Authors
  1. Emre Vural
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  2. Harry L. Winfield
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  3. Alexander W. Shingleton
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  4. Thomas D. Horn
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  5. Gal Shafirstein
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Correspondence to Emre Vural.

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Vural, E., Winfield, H.L., Shingleton, A.W. et al. The effects of laser irradiation on Trichophyton rubrum growth. Lasers Med Sci 23, 349–353 (2008). https://doi.org/10.1007/s10103-007-0492-4

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  • DOI: https://doi.org/10.1007/s10103-007-0492-4

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